Results 31 to 40 of about 1,588,316 (303)

Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo released by cells and postulated to mediate functions such as intercellular communications. Recent studies have shown that long non-coding RNAs (lncRNAs) or their
Michail Spanos, Priyanka Gokulnath, Emeli Chatterjee, Guoping Li, Dimitrios Varrias, Saumya Das   +5 more
doaj   +1 more source

Extracellular vesicle-based therapeutics: Extracellular vesicles as therapeutic targets and agents.

Pharmacology and Therapeutics, 2023
Extracellular vesicles (EVs) are cell-derived membrane vesicles composed of a lipid bilayer. EVs contain biological molecules, such as nucleic acids, lipids, and proteins.
Yuki Takahashi, Y. Takakura
semanticscholar   +1 more source

Guidelines for clinical translation and commercialization of extracellular vesicles and exosomes based therapeutics

Extracellular Vesicle, 2023
Extracellular vesicles (EVs) are lipid-bilayer delimited membrane structures released by cells, and play a role in intercell communication and disease development. The Global market for EVs in diagnostic and therapeutic applications is expanding.
Ke Cheng, Raghu Kalluri
doaj   +1 more source

Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]

, 2013
Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
E. Buzás, A. Falus, Á. Kittel, Buzás, E., Kittel, Ágnes, Falus, A.   +5 more
core   +1 more source

Extracellular vesicle-mediated bilateral communication between glioblastoma and astrocytes [PDF]

, 2020
Glioblastoma the most aggressive form of brain cancer, comprises a complex mixture of tumor cells and nonmalignant stromal cells, including neurons, astrocytes, microglia, infiltrating monocytes/macrophages, lymphocytes, and other cell types.
Morsett, L.M., Broekman, M.L.D., Abels, E.R., Nieland, L., Breakefield, X.O., Lisa Nieland, Xandra O. Breakefield, Erik R. Abels, Liza M. Morsett, Marike L.D. Broekman   +9 more
core   +1 more source

Single‐vesicle imaging and co‐localization analysis for tetraspanin profiling of individual extracellular vesicles

, 2021
Extracellular vesicles (EVs) are secreted nano-sized vesicles that contain cellular proteins, lipids, and nucleic acids. Although EVs are expected to be biologically diverse, current analyses cannot adequately characterize this diversity because most are
Kang, H., Yongmin Kwon, Jingeol Lee, Johan Yi, Kang, M., Jaehun Jung, Lee, H., Lee, J., Yi, J., Chungmin Han, Minsu Kang, Jung, J., Park, J., Jaesung Park, Hyejin Kang, Han, C., Hyunjin Lee, Kwon, Y.   +17 more
core   +1 more source

Extracellular vesicles

GENETICS
Abstract Extracellular vesicles (EVs) encompass a diverse array of membrane-bound organelles released outside cells in response to developmental and physiological cell needs. EVs play important roles in remodeling the shape and content of differentiating cells and can rescue damaged cells from toxic or dysfunctional content. EVs can send
Juan Wang, Maureen M Barr, Ann M Wehman
openaire   +4 more sources

Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases [PDF]

, 2018
It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic ...
Rory R. Koenen, Koenen, Rory R.; id_orcid, Elena Aikawa, Aikawa, Elena, Koenen, Rory R.   +4 more
core   +1 more source

Routes and mechanisms of extracellular vesicle uptake

Journal of Extracellular Vesicles, 2014
Extracellular vesicles (EVs) are small vesicles released by donor cells that can be taken up by recipient cells. Despite their discovery decades ago, it has only recently become apparent that EVs play an important role in cell-to-cell communication.
L. A. Mulcahy, R. Pink, D. R. Carter
semanticscholar   +1 more source

Skin-Targeted Delivery of Extracellular Vesicle-Encapsulated Curcumin Using Dissolvable Microneedle Arrays.

Acta Biomaterialia, 2022
Therapeutic benefits of curcumin for inflammatory diseases have been demonstrated. However, curcumin's potential as a clinical therapeutic has been hindered due to its low solubility and stability in vivo.
S. Yerneni, E. Yalcintas, Jason D. Smith, Saadyah E. Averick, P. Campbell, O. B. Ozdoganlar   +5 more
semanticscholar   +1 more source