Results 51 to 60 of about 1,588,316 (303)

Extracellular vesicle PD-L1 in reshaping tumor immune microenvironment: biological function and potential therapy strategies

Cell communication and signaling : CCS, 2022
Programmed cell death 1 ligand 1 (PD-L1) is the ligand for programmed death protein-1 (PD-1), is associated with immunosuppression. Signaling via PD-1/PD-L1 will transmits negative regulatory signals to T cells, inducing T-cell inhibition, reducing CD8 +
Jiaxing Liu, Xue-Qiang Peng, Shuo Yang, Xinyu Li, Ming-Yao Huang, Shi-Bo Wei, Sheng Zhang, Guangpeng He, Hong-Yu Zheng, Qing Fan, Liang Yang, Hang-Yu Li   +11 more
semanticscholar   +1 more source

Complex RNA world in small extracellular vesicles for liquid biopsy in cancer management

Extracellular Vesicle, 2022
Liquid biopsy is a valuable tool in oncology with its advantages of non-invasiveness, longitudinal sampling, and capturing the intra- and inter-tumor heterogeneity. Small extracellular vesicles (sEVs) are released by cells into various biological fluids,
Shuhong Wang, Yusheng Lin, Yishi Zhang, Xiaofu Qiu, Yunlong Pan, Sai-Ching Jim Yeung, Hao Zhang   +6 more
doaj   +1 more source

Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies

Signal Transduction and Targeted Therapy
Extracellular vesicles share lipid‒protein membranes with their parent cells, allowing for the targeted transfer of bioactive cargo to recipient cells for functional modulation.
Gang-Ling Xu, Jing Jin, Zhi-Hao Fu, Guang-Ming Wang, Xin-Hua Lei, Jun Xu, Jun-Zhi Wang   +6 more
semanticscholar   +1 more source

Uptake, functionality, and re-release of extracellular vesicle-encapsulated cargo

Cell Reports, 2022
SUMMARY Extracellular vesicles (EVs) are membrane-encapsulated particles that carry genetically active and protein/lipid cargo that can affect the function of the recipient cell.
K. O'Brien, S. Ughetto, Shadi Mahjoum, Anil V. Nair, X. Breakefield   +4 more
semanticscholar   +1 more source

Analysis of molecular mechanisms of extracellular vesicle formation and development of technologies for profiling extracellular vesicle heterogeneity [PDF]

岩手大学博士（学術）原著論文 Maeda, K., Goto, S., Miura, K., Saito, K., Morita, E. The Incorporation of Extracellular Vesicle Markers Varies Among Vesicles with Distinct Surface Charges The Journal of Biochemistry 175 (3), 299-312, 2024doctoral ...
前⽥, 昂樹
core   +1 more source

Extracellular RNA in oncogenesis, metastasis and drug resistance

RNA Biology
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological state ...
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton   +8 more
doaj   +1 more source

Sucrose-based cryoprotective storage of extracellular vesicles

Extracellular Vesicle, 2022
Advancements in extracellular vesicle (EV) studies necessitate the development of optimized storage conditions to ensure preservation of physical and biochemical characteristics.
Sierra A. Walker, Irina Davidovich, Yubo Yang, Andrew Lai, Jenifer Pendiuk Goncalves, Vatsal Deliwala, Sara Busatto, Shane Shapiro, Na’ama Koifman, Carlos Salomon, Yeshayahu Talmon, Joy Wolfram   +11 more
doaj   +1 more source

Boosting extracellular vesicle secretion

Biotechnology Advances, 2022
In recent years, extracellular vesicles (EVs), specifically exosomes, have emerged as a promising strategy for treating a wide spectrum of pathologies, such as cancer and COVID-19, as well as promoting tissue regeneration in various conditions, including
Lior Debbi, Shao-Wei Guo, Dina Safina, S. Levenberg   +3 more
semanticscholar   +1 more source

Extracellular vesicle-derived microbiome obtained from exhaled breath condensate in patients with asthma

, 2021
Extracellular vesicle-derived microbiome obtained from exhaled breath condensate in patients with ...
김태범, Andrea McDowell, 안진, 김윤근   +3 more
core   +1 more source

Ca2+ mediates extracellular vesicle biogenesis through alternate pathways in malignancy. [PDF]

, 2020
Extracellular vesicles (EVs) are small extracellular membrane vesicles that serve as important intercellular signalling intermediaries in both malignant and non-malignant cells.
Mary Bebawy, Iman Azimi, Monteith, G, Jack Taylor, Taylor, J, Azimi, I, Bebawy, M, Gregory Monteith   +7 more
core   +1 more source