Results 71 to 80 of about 1,588,316 (303)

Secreted exosomes induce filopodia formation

eLife
Filopodia are dynamic adhesive cytoskeletal structures that are critical for directional sensing, polarization, cell-cell adhesion, and migration of diverse cell types. Filopodia are also critical for neuronal synapse formation.
Caitlin McAtee, Mikin R Patel, Daisuke Hoshino, Bong Hwan Sung, Ariana K von Lersner, Mingjian Shi, Nan Hyung Hong, Anna Young, Evan Krystofiak, Andries Zijlstra, Alissa M Weaver   +10 more
doaj   +1 more source

Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications

Nature Nanotechnology
Extracellular vesicles (EVs) are diverse nanoparticles with large heterogeneity in size and molecular composition. Although this heterogeneity provides high diagnostic value for liquid biopsy and confers many exploitable functions for therapeutic ...
Randy P. Carney, Rachel R. Mizenko, B. Bozkurt, Neona M. Lowe, T. Henson, Alessandra Arizzi, Ai-Jun Wang, Cheemeng Tan, Steven C. George   +8 more
semanticscholar   +1 more source

Considerations for extracellular vesicle and lipoprotein interactions in cell culture assays

Journal of Extracellular Vesicles, 2022
With an exponential increase in extracellular vesicle (EV) studies in the past decade, focus has been placed on standardization of experimental design to ensure inter‐study comparisons and validity of conclusions.
S. Busatto, Yubo Yang, Dalila Iannotta, Irina Davidovich, Y. Talmon, Joy Wolfram   +5 more
semanticscholar   +1 more source

Extracellular Vesicles as Drug Transporters

International Journal of Molecular Sciences, 2023
Extracellular vesicles (EVs) are lipid bilayer-delimited particles. According to their size and synthesis pathway, EVs can be classified into exosomes, ectosomes (microvesicles), and apoptotic bodies. Extracellular vesicles are of great interest to the scientific community due to their role in cell-to-cell communication and their drug-carrying ...
Monika Nowak, Julia Górczyńska, Katarzyna Kołodzińska, Jakub Rubin, Anna Choromańska   +4 more
openaire   +3 more sources

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes [PDF]

, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Szabó, Tamas G, Szabó, Tamás G., Buzás, Edit Irén, Lötvall, Jan, Jan Lötvall, Lässer, Cecilia, Dianzani, Irma, Irma Dianzani, Edit I. Buzás, Jan Lötvall, Buzás, Edit I, Maria Eldh, Crescitelli, Rossella, Kittel, Ágnes, Eldh, Maria, Rossella Crescitelli, Agnes Kittel, Tamas G. Szabó, Edit I. Buzás, Cecilia Lässer, Tamas G. Szabó, Cecilia Lässer, Eldh, Maria,, Lässer, Cecilia,, Lötvall, Jan,, Crescitelli, Rossella,   +25 more
core   +1 more source

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation [PDF]

, 2021
Extracellular vesicles (EVs) are important players in cell to cell communication in reproductive systems. Notably, EVs have been found and characterized in the male reproductive tract, however, direct functional evidence for their importance in mediating
Hewafonsekage Fonseka (9478169), Diana Tran (2067106), Macarena B. Gonzalez, Rebecca L Robker (11233974), Mathivanan, S., Thuy Tien Nguyen, Tran, N., Andrew I. Webb, Gonzalez, MB, Macarena B Gonzalez (11233968), Natalie J Foot (11233965), Robker, RL, Mathivanan, S, Thi Thuy Dung Nguyen (9480896), Andrew I Webb (9751007), Jarrod J Sandow (9393746), Fonseka, P., Gembus, K., Webb, AI, Pamali Fonseka, Pamali Fonseka (9478169), Kelly Gembus (11233971), Kumar, S., Suresh Mathivanan (9487679), Nguyen, T.T., Sharad Kumar (52650), Sandow, J.J., Robker, R.L., Natalie J. Foot, Kelly Gembus, Jarrod J. Sandow, Rebecca L. Robker, Foot, N.J., Webb, A.I., Fonseka, P, Kumar, S, Gonzalez, M.B., Tran, D, Foot, NJ, Sandow, JJ, Suresh Mathivanan, Nguyen, TT, Diana Tran, Sharad Kumar, Gembus, K   +44 more
core   +1 more source

A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)

eLife
Recent studies showed an unexpected complexity of extracellular vesicle (EV) biogenesis pathways. We previously found evidence that human colorectal cancer cells in vivo release large multivesicular body-like structures en bloc.
Tamás Visnovitz, Dorina Lenzinger, Anna Koncz, Péter M Vizi, Tünde Bárkai, Krisztina V Vukman, Alicia Galinsoga, Krisztina Németh, Kelsey Fletcher, Zsolt I Komlósi, Csaba Cserép, Ádám Dénes, Péter Lőrincz, Gábor Valcz, Edit I Buzas   +14 more
doaj   +1 more source

Comparative Analysis of the Minimal information for studies of extracellular vesicles Guidelines: Advancements and Implications for Extracellular Vesicle Research.

Seminars in Cancer Biology
In 2014, the International Society for Extracellular Vesicles (ISEV) introduced the Minimal Information for Studies of Extracellular Vesicles (MISEV) guidelines to establish standards for extracellular vesicle (EV) research.
Elisavet Maria Vaiaki, Marco Falasca
semanticscholar   +1 more source

Extracellular vesicle‐mediated delivery of circDYM alleviates CUS‐induced depressive‐like behaviours

Journal of Extracellular Vesicles, 2022
Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and severely limits psychosocial function and quality of life, but no effective medication is currently available.
Xiao-Yu Yu, Ying Bai, Bing Han, Minzi Ju, Tian-Ci Tang, Ling Shen, Ming-Yue Li, Li Yang, Zhao Zhang, Guo-Ku Hu, J. Chao, Yuan Zhang, Hong-Hong Yao   +12 more
semanticscholar   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source