Results 271 to 280 of about 120,442 (308)

CD68 Antigen and Cerebral Aneurysms: A Case-Control Study

Journal of Neurological Surgery Part A: Central European Neurosurgery, 2023
Abstract Background Intracranial aneurysms are more commonly associated with inflammation as a cause of their development, progression, and rupture. Macrophages and other cells can express the CD68 antigen. The aim of this study was to assess the CD68 antigen levels in cerebral aneurysm (CA) patients compared to a control group at a ...
Abdolkarim Rahmanian, Ahmad Salehi, Eskandar Kamali-Sarvestani, Iman Ahrari, Ehsan Mohamadhoseini, Mohammad Jamali, Sulmaz Ghahramani   +6 more
openaire   +2 more sources

Role of CD68 in the tumor immune microenvironment in Hodgkin’s lymphoma

Expert Review of Clinical Immunology, 2023
Despite the high rate of cure in classical Hodgkin Lymphoma (cHL), some patients experienced a refractory disease, sometimes, hardly curable. In the pathogenesis of cHL, Reed Sternberg Cells (HRSC), which represent only less than 1% of tumor cells, are not the only protagonist; in fact, the role of tumor microenvironment is essential in survival, tumor
Valeria, Tomarchio, Luigi, Rigacci
openaire   +2 more sources

The CD68 Protein as a Potential Target for Leukaemia-Reactive CTL [PDF]

Leukemia, 2002
CD68, a haematopoietic differentiation marker of the monocyte-macrophage lineage, is expressed in various human malignancies including chronic and acute myeloid leukaemia (AML). While the majority of normal CD34(+) cells are negative for CD68 expression, CD34(+) cells from AML patients produce elevated amounts of this protein. The purpose of this study
Elena N. Parovichnikova, Valery Savchenko, H J Stauss   +2 more
exaly   +3 more sources

Distribution of the CD68 macrophagr/myeloid associated antigen

International Immunology, 1990
The distribution of the pan-macrophage CD68 antigen, recognized by six different monoclonal antibodies, was examined in human blood, tissue, and cell lines using APAAP staining and Western blotting. All antibodies stained monocytes and macrophages, but labelling of neutrophils, basophils, and lymphocytes was seen with some of the reagents. In addition,
K A, Pulford, A, Sipos, J L, Cordell, W P, Stross, D Y, Mason   +4 more
openaire   +2 more sources

CD68: Potential Contributor to Inflammation and RPE Cell Dystrophy

2023
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly in developed countries. It is a complex, multifactorial, progressive disease with diverse molecular pathways, including inflammation, regulating its pathogenesis.
Mayur, Choudhary, Goldis, Malek
openaire   +2 more sources

CD68 and CR3/43 Immunohistochemical Expression in Secretory Meningiomas

Neurosurgery, 2005
Secretory meningiomas (SMs) are unusual benign meningiomas. SMs are highly vascularized lesions, with angiomatous features and a perivascular arrangement, and they are accompanied frequently by massive peritumoral edema. Microglia have been called the brain's immune system, although the specific role and prognostic significance of microglia remain ...
CAFFO, Maria, CARUSO G, GERMANO', Antonino Francesco, GALATIOTO, Salvatore, MELI F, TOMASELLO, Francesco   +5 more
openaire   +4 more sources

CD68 expression in aortocoronary saphenous vein bypass grafts

Histochemistry and Cell Biology, 2012
Atherosclerosis commonly affects the arteries harvested from patients 70 years of age or older. Saphenous vein grafts appear to maintain a higher patency rate after coronary artery bypass grafting in these subjects. The infiltration of macrophages is an early step in saphenous vein graft atherosclerosis; however, little is known regarding the ...
Agnieszka, Malinska, Bartlomiej, Perek, Piotr, Buczkowski, Katarzyna, Kowalska, Danuta, Ostalska-Nowicka, Wojciech, Witkiewicz, Michal, Nowicki   +6 more
openaire   +2 more sources

CD68 and Factor Xllla Expressions in Granular-Cell Tumor of the Skin

Dermatology, 2009
Immunohistochemical and electron microscopic studies support a Schwann cell origin for most of the granular-cell tumors of the skin. We studied 9 granular-cell tumors by immunohistochemistry, using antibodies to CD68, S-100 proteins, factor XIIIa, L1 antigen, desmin and vimentin.
Nikkels, Arjen, Arrese Estrada, Jorge, Pierard-Franchimont, Claudine, Pierard, Gérald   +3 more
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CD68 identified as a regulator of human melanocyte development and function

Journal of Investigative Dermatology
This study establishes CD68, conventionally known as a macrophage marker, as a regulator of melanocyte biology. Using a human embryonic stem cell (hESC) differentiation model that replicates neural crest-derived melanocyte development, we performed single-cell RNA sequencing across five critical developmental timepoints (day 0, 6, 9, 11, and 25) to ...
Yating Liu, Xuanhao Zeng, Shiyi Huang, Yiting Jin, Qing Zang, Jiawang Chen, Weilin Lian, Jiayi Shen, Jinqi Wang, Haozhen Lv, Jinhua Xu, Qi Zhang   +11 more
openaire   +2 more sources

[Epitope analysis of CD68 antigens].

Allergie und Immunologie, 1992
Different epitopes of CD68 antigen are detectable by three new generated monoclonal antibodies (MABs) BL-M68/1-3 (all mouse IgM). The MAB BL-M68/3 reacts with an epitope, which is stable also in formalin-fixed paraffin-embedded tissues. In immunohistochemical blocking experiments using the own biotinylated MABs and six CD68 MABs from the IV.
D, Ulsijchutagijn, H, Kupper, W, Eichler, H, Fiebig   +3 more
openaire   +1 more source