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CD68: Potential Contributor to Inflammation and RPE Cell Dystrophy

2023
Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly in developed countries. It is a complex, multifactorial, progressive disease with diverse molecular pathways, including inflammation, regulating its pathogenesis.
Mayur, Choudhary, Goldis, Malek
openaire   +2 more sources

CD68 and CR3/43 Immunohistochemical Expression in Secretory Meningiomas

Neurosurgery, 2005
Secretory meningiomas (SMs) are unusual benign meningiomas. SMs are highly vascularized lesions, with angiomatous features and a perivascular arrangement, and they are accompanied frequently by massive peritumoral edema. Microglia have been called the brain's immune system, although the specific role and prognostic significance of microglia remain ...
CAFFO, Maria   +5 more
openaire   +4 more sources

CD68 expression in aortocoronary saphenous vein bypass grafts

Histochemistry and Cell Biology, 2012
Atherosclerosis commonly affects the arteries harvested from patients 70 years of age or older. Saphenous vein grafts appear to maintain a higher patency rate after coronary artery bypass grafting in these subjects. The infiltration of macrophages is an early step in saphenous vein graft atherosclerosis; however, little is known regarding the ...
Agnieszka, Malinska   +6 more
openaire   +2 more sources

CD68 and Factor Xllla Expressions in Granular-Cell Tumor of the Skin

Dermatology, 2009
Immunohistochemical and electron microscopic studies support a Schwann cell origin for most of the granular-cell tumors of the skin. We studied 9 granular-cell tumors by immunohistochemistry, using antibodies to CD68, S-100 proteins, factor XIIIa, L1 antigen, desmin and vimentin.
Nikkels, Arjen   +3 more
openaire   +2 more sources

CD68 identified as a regulator of human melanocyte development and function

Journal of Investigative Dermatology
This study establishes CD68, conventionally known as a macrophage marker, as a regulator of melanocyte biology. Using a human embryonic stem cell (hESC) differentiation model that replicates neural crest-derived melanocyte development, we performed single-cell RNA sequencing across five critical developmental timepoints (day 0, 6, 9, 11, and 25) to ...
Yating Liu   +11 more
openaire   +2 more sources

[Epitope analysis of CD68 antigens].

Allergie und Immunologie, 1992
Different epitopes of CD68 antigen are detectable by three new generated monoclonal antibodies (MABs) BL-M68/1-3 (all mouse IgM). The MAB BL-M68/3 reacts with an epitope, which is stable also in formalin-fixed paraffin-embedded tissues. In immunohistochemical blocking experiments using the own biotinylated MABs and six CD68 MABs from the IV.
D, Ulsijchutagijn   +3 more
openaire   +1 more source

CD68

1997
A. Neil Barclay   +5 more
openaire   +1 more source

Myeloid-restricted CD68 deficiency attenuates atherosclerosis via inhibition of ROS-MAPK-apoptosis axis

Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2023
Yinming Liang   +2 more
exaly  

Fibrolamellar carcinomas are positive for CD68

Yearbook of Pathology and Laboratory Medicine, 2012
openaire   +1 more source

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