S100, CD68, and MHC class II molecule expression in cervical high- and low-grade HPV-induced lesions [PDF]
Revista Da Sociedade Brasileira De Medicina Tropical, 2012 INTRODUCTION: Some human papillomavirus (HPV) types are involved in malignant processes in the cervical epithelium, with 99% of cases attributed to oncogenic HPV infection. This study aimed to detect S100, CD68, and major histocompatibility complex class
CARLOS Eurico Fernandes
exaly +6 more sources
Therapeutic targets established in adult ulcerative colitis exhibit correlations with disease severity and pathological relevance in pediatric pouchitis [PDF]
Scientific ReportsPediatric pouchitis has no established treatment strategy, and management is particularly challenging in recurrent or antibiotic-refractory cases. Tumor necrosis factor alpha (TNF-α) and mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) are ...
Sayaka Otake +17 more
doaj +2 more sources
HBx promotes podocyte-macrophage transdifferentiation by mediating NLRP3 expression in hepatitis B virus-associated glomerulonephritis [PDF]
Virology JournalBackground Podocytes are identified as main injury targets in the pathogenesis of hepatitis B virus (HBV)-associated glomerulonephritis (HBV-GN). NLR family pyrin domain containing 3 (NLRP3) has a critical function in inducing podocyte injury across ...
Zhaotun He +4 more
doaj +2 more sources
Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing MacrophagesSummaryWhat You Need to Know [PDF]
Cellular and Molecular Gastroenterology and HepatologyBackground & Aims: The liver undergoes significant hemodynamic changes during surgery, transplantation, or cirrhosis with portal hypertension (PH).
Ruixue Ma +10 more
doaj +2 more sources
Revista Científica, 2023 This study aimed to investigate the effect of Aspalathus linearis on the expression levels of major histocompatibility complex (MHC) molecules and their ability to present antigens to CD8, CD68, and T cells in an experimental rat model of gastritis ...
İdris Oruç +6 more
doaj +1 more source
Role of CD68 in tumor immunity and prognosis prediction in pan-cancer
Scientific Reports, 2022 CD68 plays a critical role in promoting phagocytosis; however, the function of CD68 in tumor immunity and prognosis remains unknown. We analyzed CD68 expression among 33 tumor and normal tissues from The Cancer Genome Atlas and Genotype-Tissue Expression
Jingwei Zhang +3 more
doaj +1 more source
A Potential Inhibitory Profile of Liver CD68+ Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 but Not CD86 Expression. [PDF]
PLoS ONE, 2016 AIM:The lack of potent innate immune responses during HCV infection might lead to a delay in initiating adaptive immune responses. Kupffer cells (KCs) and liver-infiltrating monocytes/macrophages (CD68+ cells) are essential to establish effective anti ...
Elias A Said +9 more
doaj +1 more source
PD-L1 is upregulated in CD163+ tonsillar macrophages from children undergoing EBV primary infection
Frontiers in Immunology, 2022 Epstein–Barr Virus (EBV) is a tumor associated virus that modulates not only the infected cells but also innate and adaptive immunity. Macrophages play a key role in tumor development and progression.
Agustina Moyano +5 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Bazi Bushen capsule (BZBS), as a Chinese medicine used to relieve fatigue, has been proven effective for the treatment of atherogenesis through antilipid effects. To investigate the potential mechanism of BZBS in the anti-atherosclerotic effect, Ovx/ApoE-
Dan Huang +13 more
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(18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers. [PDF]
PLoS ONE, 2012 AIM: To study whether (18)F-FDG can be used for in vivo imaging of atherogenesis by examining the correlation between (18)F-FDG uptake and gene expression of key molecular markers of atherosclerosis in apoE(-/-) mice.
Anne Mette Fisker Hag +8 more
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