Results 11 to 20 of about 35,344 (261)

SOD3 reduces inflammatory cell migration by regulating adhesion molecule and cytokine expression. [PDF]

PLoS ONE, 2009
Inflammatory cell migration characteristic of ischemic damages has a dual role providing the tissue with factors needed for tissue injury recovery simultaneously causing deleterious development depending on the quality and the quantity of infiltrated ...
Juha P Laurila, Lilja E Laatikainen, Maria D Castellone, Mikko O Laukkanen   +3 more
doaj   +2 more sources

3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer’s disease via machine learning

Acta Neuropathologica Communications
Alzheimer’s Disease (AD) is a debilitating neurodegenerative disease that affects 47.5 million people worldwide. AD is characterised by the formation of plaques containing extracellular amyloid-β (Aβ) and neurofibrillary tangles composed of hyper ...
Wissam B. Nassrallah, Hao Ran Li, Lyden Irani, Printha Wijesinghe, Peter William Hogg, Lucy Hui, Jean Oh, Ian R. Mackenzie, Veronica Hirsch-Reinshagen, Ging-Yuek Robin Hsiung, Wellington Pham, Sieun Lee, Joanne A. Matsubara   +12 more
doaj   +2 more sources

Tumor site immune markers associated with risk for subsequent basal cell carcinomas. [PDF]

PLoS ONE, 2011
BackgroundBasal cell carcinoma (BCC) tumors are the most common skin cancer and are highly immunogenic.ObjectiveThe goal of this study was to assess how immune-cell related gene expression in an initial BCC tumor biopsy was related to the appearance of ...
Ronald Glaser, Rebecca Andridge, Eric V Yang, Arwa Y Shana'ah, Michael Di Gregorio, Min Chen, Sheri L Johnson, Lawrence A De Renne, David R Lambert, Scott D Jewell, Mark A Bechtel, Dean W Hearne, Joel Bain Herron, Janice K Kiecolt-Glaser   +13 more
doaj   +2 more sources

The germline HLA-A02B62 supertype is associated with a PD-L1-positive tumour immune microenvironment and poor prognosis in stage I lung cancer

Heliyon, 2023
Background: Germline HLA class I molecule supertypes are shown to correlate with response to anti-PD-1 therapy. Here, we investigate the significance of germline HLA-A and HLA-B supertypes in tumour microenvironment of non-small-cell lung cancer. Methods:
Ruijiang Lin, Xiaohua Chen, Fei Su, Hongbin Wang, Biao Han, Yanhui Chen, Cuixiang Zhang, Minjie Ma   +7 more
doaj   +1 more source

Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway

BMC Cancer, 2020
Background Alternatively-activated macrophages (AAMs), an anti-inflammatory macrophage subpopulation, have been implicated in the progression of high grade serous ovarian carcinoma (HGSOC). Increased levels of AAMs are correlated with poor HGSOC survival
Kaitlin C. Fogg, Andrew E. Miller, Ying Li, Will Flanigan, Alyssa Walker, Andrea O’Shea, Christina Kendziorski, Pamela K. Kreeger   +7 more
doaj   +1 more source

Loss of SENP3 mediated the formation of nasal polyps in nasal mucosal inflammation by increasing alternative activated macrophage

Immunity, Inflammation and Disease, 2023
Background and Aim Small ubiquitin–like modifier (SUMO)‐specific protease (SENP)3 is a protease molecule that responds to reactive oxygen species (ROS) with high sensitivity.
Ximing Bao, Bin Liu, Yongquan Jiang, Tingting Feng, Wanxin Cao, Jiali Shi, Yiming Jiang, Xiaorui Chen, Jie Yang, Jiping Li, Zheng Zhou   +10 more
doaj   +1 more source

High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis

Frontiers in Oncology, 2021
BackgroundLymphoma-associated macrophages (LAMs) are key components in the lymphoma microenvironment, which may impact disease progression and response to therapy. There are two major subtypes of LAMs, CD68+ M1 and CD163+ M2.
Philippa Li, Ji Yuan, Ji Yuan, Fahad Shabbir Ahmed, Fahad Shabbir Ahmed, Austin McHenry, Kai Fu, Kai Fu, Guohua Yu, Guohua Yu, Hongxia Cheng, Hongxia Cheng, Mina L. Xu, David L. Rimm, Zenggang Pan   +14 more
doaj   +1 more source

Table_1_High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis.xlsx

, 2021
BackgroundLymphoma-associated macrophages (LAMs) are key components in the lymphoma microenvironment, which may impact disease progression and response to therapy. There are two major subtypes of LAMs, CD68+ M1 and CD163+ M2.
Guohua Yu (176526), Zenggang Pan (11354091), Hongxia Cheng (11354085), Austin McHenry (11354082), Philippa Li (11354076), Mina L. Xu (11354088), Fahad Shabbir Ahmed (11354079), Kai Fu (19063), David L. Rimm (6947141), Ji Yuan (8222955)   +9 more
core   +1 more source

Table_2_High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis.xlsx

, 2021
BackgroundLymphoma-associated macrophages (LAMs) are key components in the lymphoma microenvironment, which may impact disease progression and response to therapy. There are two major subtypes of LAMs, CD68+ M1 and CD163+ M2.
Guohua Yu (176526), Zenggang Pan (11354091), Hongxia Cheng (11354085), Austin McHenry (11354082), Philippa Li (11354076), Mina L. Xu (11354088), Fahad Shabbir Ahmed (11354079), Kai Fu (19063), David L. Rimm (6947141), Ji Yuan (8222955)   +9 more
core   +1 more source

Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model

, 2021
BACKGROUND: Fractalkine receptor 1 (CX3CR1) mediates macrophage infiltration and accumulation, causing venous neointimal hyperplasia (VNH)/venous stenosis (VS) in arteriovenous fistula (AVF). The effect of blocking CX3CR1 using an anti–human variable VHH
Chih-Cheng Wu, Vazquez-Padron, Roberto I., Amit Sharma, Roberto I. Vazquez-Padron, Kilari, Sreenivasulu, Sharma, Amit, Yang, Binxia, John Broadwater, Misra, Sanjay, Sreenivasulu Kilari, Binxia Yang, Wu, Chih-Cheng, Broadwater, John, Vazquez-Padron, Roberto I, Sanjay Misra   +14 more
core   +1 more source