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Regional differences in the density of Langerhans cells, CD8-positive T lymphocytes and CD68-positive macrophages : a preliminary study using elderly donated cadavers

open access: yesRegional differences in the density of Langerhans cells, CD8-positive T lymphocytes and CD68-positive macrophages : a preliminary study using elderly donated cadavers
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Decreases of CD4‐ and CD8‐positive T lymphocytes in retired chromate workers

American Journal of Industrial Medicine, 1995
AbstractTo investigate the effects of chromates on the human immune system, we measured total T lymphocytes and their two major subpopulations (CD4 + and CD8 + T lymphocytes) in the peripheral blood of 19 retired male workers who had been exposed to chromate at a chemical plant.
T, Tanigawa   +4 more
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Autoantibodies against CD4- and CD8-Positive T Lymphocytes in HIV-Infected Hemophilia Patients

Vox Sanguinis, 1989
The presence of IgG, IgM, C3d, or gp120 on the surface of T lymphocytes was analyzed by flow cytometry in blood samples from 73 hemophilia patients and 56 healthy controls. IgG and IgM autoantibodies against CD4+ lymphocytes were found in HIV + patients but not in HIV-patients or healthy controls (p less than 0.001).
V, Daniel   +3 more
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Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1

The Lancet, 1996
Summary Background Although lymphocytes expressing the CD4 surface receptor for HIV-1 have been identified as the principal target of the virus, the extent to which infection of other cell types of the immune system contributes to immunodeficiency is unknown.
WJ Livingstone   +4 more
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CD28–Negative CD8–Positive Cytotoxic T Lymphocytes Mediate Hepatocellular Damage in Hepatitis C Virus Infection

Journal of Clinical Immunology, 2003
The pathogenic mechanism for hepatocellular damage in hepatitis C virus (HCV) infection has not been clearly understood. Analysis of costimulatory molecules on lymphocytes may give us insight into the pathogenic mechanism of hepatocellular damage in HCV infection.
Kazutaka, Kurokohchi   +10 more
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Radiosensitivity of CD4 or CD8 Positive Human T-Lymphocytes by an in Vitro Colony Formation Assay

Radiation Research, 1990
The recent development of an in vitro lymphocyte colony assay makes it possible to examine variations in the radiosensitivity of humans using peripheral blood lymphocytes (PBL) instead of the skin fibroblast assay. Our recent study (M. Hakoda et al., Mutat. Res.
N, Nakamura, Y, Kusunoki, M, Akiyama
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Mink infected with aleutian disease virus have an elevated level of CD8-positive T-lymphocytes

Veterinary Immunology and Immunopathology, 1989
Lymphocytes, monocytes, granulocytes, B-lymphocytes and CD8-positive T-lymphocytes of non-infected mink and mink infected with Aleutian disease virus (ADV) were measured by flow cytometry. The gammaglobulin levels of the sera were also measured. Besides development of hypergammaglobulinaemia in the infected mink, the most pronounced finding was that ...
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DIFFERENTIAL REGULATION OF ACTIVATION-ASSOCIATED RECEPTOR EXPRESSION ON CD4− AND CD8-POSITIVE T LYMPHOCYTES BY ALLOSENSITIZED SUPPRESSOR T CELLS

Transplantation, 1989
We have demonstrated by two-color flow cytometry that allosensitized human suppressor T cells thwart progression of alloactivated T cells into the G1B stage of the cell cycle, and consequently prevent the expression of transferrin receptors on the majority of alloreactive MLR responder cells (P less than 0.005).
R, Loertscher, T B, Strom
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Preferential clonogenic deficit of CD8-positive T-lymphocytes infiltrating human solid tumors.

Cancer research, 1989
The vast majority of tumor infiltrating lymphocytes (TIL) are either CD4+ or CD8+ T-lymphocytes. In order to examine directly the functional capabilities of the individual CD4+ and CD8+ TIL subsets we performed cell sorting of double immunofluorescence-labeled TIL recovered from 15 biopsies by enzyme digestion.
S, Miescher   +5 more
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Complement Receptor Type 1 (CR1, CD35) Expression on Peripheral T Lymphocytes: Both CD4- and CD8-Positive Cells Express CR1

Complement and Inflammation, 1991
T lymphocytes from 42 healthy blood donors were examined for expression of CR1 on the cell surface using a fluorescence-activated cell sorter. The fraction of CR1-positive T lymphocytes varied in the range from 1 to 8% (median 2.4%). The CR1-positive T lymphocytes constituted a homogeneous group of cells regarding both size and granulation; they seemed
A, Rødgaard   +4 more
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