Results 101 to 110 of about 436,454 (294)
Increased IL-15 Production and Accumulation of Highly Differentiated CD8+ Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus [PDF]
, 2017 Luca Pangrazzi +6 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim +16 more
wiley +1 more source
Enforced Expression of GATA-3 During T Cell Development Inhibits Maturation of CD8 Single-Positive Cells and Induces Thymic Lymphoma in Transgenic Mice [PDF]
, 2001 Martijn C. Nawijn +7 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Increased frequency of TIGIT + CD73-CD8 + T cells with a TOX + TCF-1low profile in patients with newly diagnosed and relapsed AML [PDF]
, 2021 Franziska Brauneck +11 more
openalex +1 more source
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Advanced Healthcare Materials, EarlyView.Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source
Infectio, 2008 Objetivo. La coexpresión en membrana de las moléculas CD4 y CD8 en leucocitos de sangre periférica se halla generalmente restringida a casos de leucemias agudas T prolinfocíticas o de leucemias T del adulto y no representa más de 3% a 5% de los ...
Alberto Gómez +4 more
doaj
B Cells and CD4−CD8− T Cells Are Key Regulators of the Severity of Reactivation Histoplasmosis [PDF]
, 2006 Holly Allen, George S. Deepe
openalex +1 more source
IL‐2 Free Expansion of T Cells with Immunofilaments
Advanced Healthcare Materials, EarlyView.Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source