Results 121 to 130 of about 729,582 (283)

The identity of human tissue-emigrant CD8⁺T cells [PDF]

, 2020
Marcus Buggert, Laura A. Vella, Son Nguyen, Vincent H. Wu, Takuya Sekine, André Perez‐Potti, Colby R. Maldini, Sasikanth Manne, Samuel Darko, Amy Ransier, Leticia Kuri-Cervantes, Alberto Sada Japp, Irene Bukh Brody, Martin A. Ivarsson, Laura Hertwig, Jack P. Antel, Matthew E. Johnson, Afam A. Okoye, Louis J. Picker, Golnaz Vahedi, Ernesto Sparrelid, Sian Llewellyn‐Lacey, Emma Gostick, Niklas K. Björkström, Amit Bar‐Or, Yoav Dori, Ali Naji, David H. Canaday, Terri M. Laufer, Andrew D. Wells, David A. Price, Ian Frank, Daniel C. Douek, E. John Wherry, Maxim Itkin, Michael R. Betts   +35 more
openalex   +1 more source

Supplementary Figure 1 from The Immune Signature of CD8⁺CCR7⁺ T Cells in the Peripheral Circulation Associates with Disease Recurrence in Patients with HNSCC [PDF]

, 2023
Malgorzata Czystowska, William E. Gooding, Mirosław J. Szczepański, Andres Lopez-Abaitero, Robert L. Ferris, Jonas T. Johnson, Theresa L. Whiteside   +6 more
openalex   +1 more source

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

Advanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri, Renata Maia, Pei Zhang, Liliana Agresti, Jelmer Sjollema, Mohammad‐Ali Shahbazi, Hélder A. Santos   +6 more
wiley   +1 more source

Coexpresión de CD4 y CD8 en linfocitos de sangre periférica en pacientes positivos para VIH Peripheral blood lymphocyte CD4 and CD8 co-expression in HIV positive patients

Infectio, 2008
Objetivo. La coexpresión en membrana de las moléculas CD4 y CD8 en leucocitos de sangre periférica se halla generalmente restringida a casos de leucemias agudas T prolinfocíticas o de leucemias T del adulto y no representa más de 3% a 5% de los ...
Alberto Gómez, Claudia González, Luz Mábel Ávila, María Consuelo Casas, Santiago Padilla   +4 more
doaj  

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

CD69+CD103+CD8+ tissue-resident memory T cells possess stronger anti-tumor activity and predict better prognosis in colorectal cancer

Cell Communication and Signaling
Background Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Despite advancements in therapeutic methodologies, it still causes a high rate of patient mortality. CD8+ tissue-resident memory T (TRM) cells are strategically positioned
Zi-Xin Wu, Tian-Tian Da, Chuan Huang, Xiao-Qing Wang, Liang Li, Zhi-Bin Zhao, Ting-Ting Yin, Hai-Qing Ma, Zhe-Xiong Lian, Jie Long, Fei Wang, Jie Cao   +11 more
doaj   +1 more source

Supplemental Table 1 from Molecular Programming of Tumor-Infiltrating CD8⁺ T Cells and IL15 Resistance [PDF]

, 2023
Andrew L. Doedens, Mark P. Rubinstein, Emilie Gross, J. Adam Best, David Craig, Megan K. Baker, David J. Cole, Jack D. Bui, Ananda W. Goldrath   +8 more
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Low CD8+ T Cell Infiltration and High PD-L1 Expression Are Associated with Level of CD44+/CD133+ Cancer Stem Cells and Predict an Unfavorable Prognosis in Pancreatic Cancer [PDF]

, 2019
Ya-Chin Hou, Ying‐Jui Chao, Min-Hua Hsieh, Hui-Ling Tung, Hao‐Chen Wang, Yan‐Shen Shan   +5 more
openalex   +1 more source

Generation of Cytotoxic T cells and Dysfunctional CD8 T Cells in Severe COVID19 Patients

, 2022
Sarah Cristina Gozzi-Silva, Luana de Mendonça Oliveira, Ricardo Wesley Alberca, Nátalli Zanete Pereira, Fábio Seiti Yamada Yoshikawa, Anna Julia Pietrobon, Tatiana Mina Yendo, Milena Mary de Souza Andrade, Yasmim Álefe Leuzzi Ramos, Cyro Alves de Brito, Emily Araújo Oliveira, Danielle Rosa Beserra, Alberto José da Silva Duarte, Maria Notomi Sato   +13 more
openalex   +2 more sources