Results 141 to 150 of about 436,454 (294)

Dependence of CD8 T Cell Response upon Antigen Load During Primary Infection

, 2019
Mia Moore, Hasan Ahmed, Donald J. McGuire, Rama Akondy, Rafi Ahmed, Rustom Antia   +5 more
openalex   +2 more sources

Role of CD8 T cell subsets in the pathogenesis of multiple sclerosis [PDF]

, 2011
Amit Saxena, Guillaume Martin‐Blondel, Lennart T. Mars, Roland Liblau   +3 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

CD318 expression defines a novel subset of human CD8⁺ regulatory T cells. [PDF]

Sci Adv
Do JS, Chen WK, Hung YW, Arribas-Layton D, Lu C, Gu A, Montero E, Carmo AM, Reijonen H.   +8 more
europepmc   +1 more source

Schistosomal egg antigen‐responsive CD8 T‐cell population in Schistosoma mansoni‐infected BALB/c mice

, 1999
Véronique Pancré, Myriam Delacre, Josiane Herno, Claude Auriault   +3 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Targeting macrophage-derived SPP1 enhances CD8 T cell infiltration via ROS-DNA fragment/cGAS-STING/STAT1-mediated CXCL9/10 in tumor microenvironment. [PDF]

J Immunother Cancer
Wang J, Shi Y, Gao Y, Zhu N, Liu Y, Zhang Y, Xu C, Yang R.   +7 more
europepmc   +1 more source

Belatacept-Resistant Rejection Is Associated With CD28+ Memory CD8 T Cells [PDF]

, 2017
David V. Mathews, W. Wakwe, S.C. Kim, Michael Lowe, Cynthia Breeden, Mustimbo Roberts, Alton B. Farris, Elizabeth Strobert, Joseph Jenkins, Christian P. Larsen, Mandy L. Ford, Robert Townsend, Andrew Adams   +12 more
openalex   +1 more source

Data from Ncoa2 Promotes CD8⁺ T cell–Mediated Antitumor Immunity by Stimulating T-cell Activation via Upregulation of PGC-1α Critical for Mitochondrial Function

, 2023
Xiancai Zhong, Hongmin Wu, Ching Ouyang, Wencan Zhang, Yun Shi, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun   +9 more
openalex   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source