THE ROLE OF CD8+ AND CD4+ CELLS IN REJECTION OF MULTIPLE MINOR H-DISPARATE SKIN GRAFTS
TAKERU ICHIKAWA+8 more
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Major histocompatibility complex-expressing nonhematopoietic astroglial cells prime only CD8+ T lymphocytes: astroglial cells as perpetuators but not initiators of CD4+ T cell responses in the central nervous system. [PDF]
JD Sedgwick+3 more
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Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen+16 more
wiley +1 more source
The characteristics of peripheral blood lymphocyte main subsets in rheumatoid arthritis patients concurrent with hepatitis b virus infection: a retrospective cohort study. [PDF]
Shao L, Shen L, Wu J.
europepmc +1 more source
CD8+ T cell response to Mls-1a determinants involves major histocompatibility complex class II molecules. [PDF]
Yolande Chvatchko, H. Robson MacDonald
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NETs‐CD44‐IL‐17A Feedback Loop Drives Th17‐Mediated Inflammation in Behçet's Uveitis
In experimental autoimmune uveitis (EAU), neutrophils interact with T helper 17 (Th17) cells through neutrophil extracellular traps (NETs) to exert a pro‐inflammatory effect. In vitro and in vivo experiments identify that NETs promote IL‐17A secretion in Th17 cells via CD44, and increasing IL‐17A further induces more NETs formation.
Yi Wu+11 more
wiley +1 more source
Assessment of antigen immunogenicity formulated in minigenes transfected into antigen-presenting cells. [PDF]
Villota-Alava MA+4 more
europepmc +1 more source
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li+19 more
wiley +1 more source
ITGB2 and ICAM3 predict increased survival of sepsis with decreased intercellular communication in cytotoxic CD8+ T cells. [PDF]
Lei M+5 more
europepmc +1 more source
Unexpected expansions of CD8-bearing cells in old mice. [PDF]
J E Callahan+2 more
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