Results 11 to 20 of about 409,454 (264)

CD8+ T Cells in Atherosclerosis [PDF]

Cells, 2020
Atherosclerotic lesions are populated by cells of the innate and adaptive immune system, including CD8+ T cells. The CD8+ T cell infiltrate has recently been characterized in mouse and human atherosclerosis and revealed activated, cytotoxic, and possibly dysfunctional and exhausted cell phenotypes.
Sarah Schäfer, Alma Zernecke
openaire   +4 more sources

The Immunomodulatory Effects of Ginger (Zingiber officinale) Extract on CD4 and CD8 Expression in Spleen of Diabetic Rats

Namık Kemal Tıp Dergisi, 2023
Aim:This study aims to examine the changes of the ginger extract treatment on CD4 and CD8 expressions in the spleen tissue of rats, in which the experimental diabetes was induced with streptozotocin.Materials and Methods:Forty Wistar albino rats were ...
Buket BAKIR
doaj   +1 more source

Collisional variant of CD8+ mycosis fungoides and indolent CD8+ lymphoid proliferation [PDF]

JAAD Case Reports, 2020
Abstract: CD8+ lymphoid infiltrates of the skin are classified into different subtypes with variable prognoses and treatment options. Here, we present a patient with CD8+ mycosis fungoides who developed CD8+ indolent lymphoid proliferation in a background of conventional plaque stage CD8+ mycosis fungoides.
Adriana Lopez, MD, Megan H. Trager, BA, Cynthia Magro, MD, Larisa J. Geskin, MD   +3 more
openaire   +3 more sources

The expression of SP263 in muscle invasive bladder carcinoma and its relationship with clinicopathological features

Indian Journal of Pathology and Microbiology, 2023
Context: The expression of programmed cell death ligand1 (PDL1) is a research hotspot of immunotherapy. The treatment targeted for its expression has shown effectiveness in many tumors. Objective: The aim of the study was to determine PD-L1 expression in
Yanfeng Bai, Xuesong Wu, Menghan Weng, Qingmei Han, Liming Xu, Chengdong Chang, Xiaodong Teng   +6 more
doaj   +1 more source

Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function [PDF]

The Journal of Immunology, 2000
Abstract To investigate the molecular basis that makes heterodimeric CD8αβ a more efficient coreceptor than homodimeric CD8αα, we used various CD8 transfectants of T1.4 T cell hybridomas, which are specific for H-2Kd, and a photoreactive derivative of the Plasmodium  berghei circumsporozoite peptide PbCS 252–260 (SYIPSAEKI).
Arcaro A, Grégoire C, Boucheron N, Stotz S, Palmer E, Malissen B, Luescher IF   +6 more
openaire   +3 more sources

Prognostic significance of OX40+ lymphocytes in tumor stroma of surgically resected small-cell lung cancer

OncoImmunology, 2021
OX40 (CD134) is a co-stimulatory molecule mostly expressed on activated T lymphocytes. Previous reports have shown that OX40 can be an immuno-oncology target and a clinical biomarker for cancers of various organs.
Hiroshi Yokouchi, Hiroshi Nishihara, Toshiyuki Harada, Toraji Amano, Takayuki Ohkuri, Shigeo Yamazaki, Hajime Kikuchi, Satoshi Oizumi, Hidetaka Uramoto, Fumihiro Tanaka, Masao Harada, Kenji Akie, Fumiko Sugaya, Yuka Fujita, Kei Takamura, Tetsuya Kojima, Mitsunori Higuchi, Osamu Honjo, Yoshinori Minami, Naomi Watanabe, Masaharu Nishimura, Hiroyuki Suzuki, Hirotoshi Dosaka-Akita, Hiroshi Isobe   +23 more
doaj   +1 more source

CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial

OncoImmunology, 2017
The French phase 3 trial (OS 2006) testing zoledronic acid, an osteoclast inhibitor, with chemotherapy and surgery did not improve the outcome of patients with osteosarcoma (OS).
Anne Gomez-Brouchet, Claire Illac, Julia Gilhodes, Corinne Bouvier, Sébastien Aubert, Jean-Marc Guinebretiere, Béatrice Marie, Frédérique Larousserie, Natacha Entz-Werlé, Gonzague de Pinieux, Thomas Filleron, Véronique Minard, Vincent Minville, Eric Mascard, François Gouin, Marta Jimenez, Marie-Cécile Ledeley, Sophie Piperno-Neumann, Laurence Brugieres, Françoise Rédini   +19 more
doaj   +1 more source

CD8+ Lymphomatoid Papulosis [PDF]

Annals of Dermatology, 2011
Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8.
Ji Hyun, Sim, You Chan, Kim
openaire   +2 more sources

ROLE OF CD95 AND DR3 RECEPTORS IN NA VE T-LYMPHOCYTES APOPTOSIS IN CHILDREN WITH INFECTIOUS MONONUCLEOSIS DURING CONVALESCENCE

Инфекция и иммунитет, 2017
Infectious mononucleosis is a widespread disease caused by certain members of Herpesviridae family. Acute infectious mononucleosis develops predominantly in children and is accompanied by an increase of the number of circulating naive CD4+ and naive CD8+
E. N. Filatova, E. V. Anisenkova, N. B. Presnyakova, E. A. Kulova, O. V. Utkin   +4 more
doaj   +1 more source

CD8+ and CD8- NKT Cells Exhibit Phenotypic Changes During Pregnancy

Immunological Investigations, 2022
NKT cell population is a relatively well-characterized immune cell subset. Numerous publications have characterized the phenotypical features of its subpopulations even in human pregnancy. Nevertheless, there have not been studies investigating the distribution of the NKT cells based on the surface presence of the CD8 receptor.
Matyas Meggyes, David U. Nagy, Iyad Saad Al Deen, Borbala Parkanyi, Laszlo Szereday   +4 more
openaire   +4 more sources