Characterisation of CD8neg and CD8+ human natural killer cell subsets [PDF]
, 2012 NK cells are CD3neg CD56+ lymphocytes that constitute about 10-15% of peripheral blood lymphocytes. They have an innate ability to recognise and kill virus infected cells and tumour cells.
Abdalla, Ibrahim.I.I.
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Dual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells [PDF]
, 2011 The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be expressed ...
Lunemann, Sebastian +35 more
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Namık Kemal Tıp Dergisi, 2023 Aim:This study aims to examine the changes of the ginger extract treatment on CD4 and CD8 expressions in the spleen tissue of rats, in which the experimental diabetes was induced with streptozotocin.Materials and Methods:Forty Wistar albino rats were ...
Buket BAKIR
doaj +1 more source
Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection. [PDF]
, 2011 During human and murine cytomegalovirus (MCMV) infection an exceptionally large virus-specific CD8 T cell pool is maintained in the periphery lifelong.
Torti, Nicole +15 more
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CD8+ T Cells in Atherosclerosis [PDF]
Cells, 2020 Atherosclerotic lesions are populated by cells of the innate and adaptive immune system, including CD8+ T cells. The CD8+ T cell infiltrate has recently been characterized in mouse and human atherosclerosis and revealed activated, cytotoxic, and possibly dysfunctional and exhausted cell phenotypes.
Sarah Schäfer, Alma Zernecke
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Human memory CD8+ T-cells exhibit an intrinsic metabolic advantage as reflected by increased mitochondrial functionality and high glycolytic potential [PDF]
, 2013 Intrinsic differences between na•ve and memory CD8+ T-cells affect both quality and quantity of cognate antigen response. Cellular immune function and metabolic pathways are closely linked.
Gubser, Patrick Marc
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Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function [PDF]
The Journal of Immunology, 2000 Abstract To investigate the molecular basis that makes heterodimeric CD8αβ a more efficient coreceptor than homodimeric CD8αα, we used various CD8 transfectants of T1.4 T cell hybridomas, which are specific for H-2Kd, and a photoreactive derivative of the Plasmodium berghei circumsporozoite peptide PbCS 252–260 (SYIPSAEKI).
Arcaro A +6 more
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Indian Journal of Pathology and Microbiology, 2023 Context: The expression of programmed cell death ligand1 (PDL1) is a research hotspot of immunotherapy. The treatment targeted for its expression has shown effectiveness in many tumors. Objective: The aim of the study was to determine PD-L1 expression in
Yanfeng Bai +6 more
doaj +1 more source
Collisional variant of CD8+ mycosis fungoides and indolent CD8+ lymphoid proliferation [PDF]
JAAD Case Reports, 2020 Abstract: CD8+ lymphoid infiltrates of the skin are classified into different subtypes with variable prognoses and treatment options. Here, we present a patient with CD8+ mycosis fungoides who developed CD8+ indolent lymphoid proliferation in a background of conventional plaque stage CD8+ mycosis fungoides.
Adriana Lopez, MD +3 more
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Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]
, 2009 Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
Hao He +13 more
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