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Differential effects of small extracellular vesicles from head and neck cancer patients on dendritic cell functions. [PDF]
Front OncolHuber D +7 more
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Langerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1-Dependent and JAK Inhibitor-Sensitive. [PDF]
AllergyDeng Y +6 more
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Tunable wrinkled topographies direct dendritic cell maturation and immune phenotypes. [PDF]
Acta BiomaterChavda A +4 more
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Expression of CD83 in the murine immune system
Medical Microbiology and Immunology, 2003CD83 is used as a marker for mature dendritic cells (DC) in man. We have developed a new monoclonal antibody (mAb), Michel-17, that specifically recognizes mouse CD83. We show that murine CD83 is expressed mainly on mature DC and on activated T cells. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of ...
Paul Rácz +2 more
exaly +3 more sources
CD83 and GRASP55 interact in human dendritic cells
Biochemical and Biophysical Research Communications, 2015CD83 is one of the best known surface markers for mature human dendritic cells (DCs). The full-length 45 kDa type-I membrane-bound form (mbCD83) is strongly glycosylated upon DCs maturation. As co-stimulatory properties of CD83 are attributed to mbCD83 surface expression is required for efficient T-cell stimulation by mature DCs.
Heinrich Sticht +2 more
exaly +3 more sources
Role of CD83 in the Immunomodulation of Dendritic Cells
International Archives of Allergy and Immunology, 2002Glycoprotein CD83 is one of the best-known maturation markers for human dendritic cells (DCs). The fact that CD83 is strongly upregulated together with co-stimulatory molecules such as CD80 and CD86 during DC maturation suggests it plays an important role in the induction of immune responses.
Matthias, Lechmann +3 more
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Enhanced Activation of CD83‐Positive T Cells*
Scandinavian Journal of Immunology, 2003AbstractCD83 is a marker molecule for mature dendritic cells (DCs) but is also substantially expressed on activated T cells in humans and mice. Its function is unknown, but CD83 knockout mice show an impaired thymic maturation of CD4‐positive cells and soluble CD83 inhibits partially antigen‐specific responses in vitro pointing to a role of CD83 in the
M, Wolenski +5 more
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CD83 regulates lymphocyte maturation, activation and homeostasis
Trends in Immunology, 2008The transmembrane CD83 molecule, a conserved member of the immunoglobulin superfamily, is known as one of the most characteristic cell surface markers for fully matured dendritic cells (DCs) in the peripheral circulation. An essential role for CD83 on murine DCs has not been found; however, evidence shows that its function primarily lies in the ...
Minka, Breloer, Bernhard, Fleischer
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CD83 is a dimer: Comparative analysis of monomeric and dimeric isoforms
Biochemical and Biophysical Research Communications, 2005Recently, we reported that soluble CD83 has a strong immunosuppressive activity in vitro as well as in vivo. Sequence alignment of CD83 between different species revealed the presence of five cysteines in the extracellular Ig-domain of the protein. This opens up the possibility that four cysteines are involved in the formation of two intramolecular ...
Matthias, Lechmann +5 more
openaire +2 more sources