Cells, 2013 Contemporary quantitative mass spectrometry provides fascinating opportunities in defining the stoichiometry of high-molecular weight complexes or multiprotein platforms.
Inna Lavrik +3 more
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Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation. [PDF]
, 2001 Ligation of the cell-surface Fas molecule by its ligand (Fas-L) or agonistic anti-Fas monoclonal antibodies results in the cleavage and activation of the cysteine protease procaspase 8 followed by the activation of procaspase 3 and by apoptosis.
Folarin, NI +8 more
core
Cohomology of affine Artin groups and applications
, 2007 The result of this paper is the determination of the cohomology of Artin groups of type A_n, B_n and \tilde{A}_{n} with non-trivial local coefficients.
Callegaro, Filippo +2 more
core +1 more source
Arachidonic acid metabolism in TNF, CD178 (CD95 ligand) and ceramide-mediated cytotoxicity
Archives of Medical Science, 2007 Introduction: Arachidonic acid release has been reported to play a significant role in TNF-induced cytotoxicity. However, the role of this signalling cascade in CD178-(CD95 ligand)mediated cytotoxicity remains unclear.
Monika Ołdak +3 more
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Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques. [PDF]
, 2020 Generating durable humoral immunity through vaccination depends upon effective interactions of follicular helper T (Tfh) cells with germinal center (GC) B cells.
Amara, Rama R +21 more
core
Dynamics within the CD95 death‐inducing signaling complex decide life and death of cells
Molecular Systems Biology, 2010 This study explores the dilemma in cellular signaling that triggering of CD95 (Fas/APO‐1) in some situations results in cell death and in others leads to the activation of NF‐κB.
Leo Neumann +7 more
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The Role of CD95 Glycosylation in CD95 Signaling
, 2010 The CD95 (APO-1/Fas)-mediated apoptotic pathway is one of the well-studied death receptor pathways. CD95 is a highly glycosylated type I transmembrane protein and has a molecular mass of 37.5 kDa. The N-terminal domain of CD95 contains two putative N-linked glycosylation sites at N118 and N136 and posttranslational glycosylation leads to an increase of
openaire +2 more sources
Unveiling hidden structures in the Coma cluster [PDF]
, 1995 We have assembled a large data-set of 613 galaxy redshifts in the Coma cluster, the largest presently available for a cluster of galaxies. We have defined a sample of cluster members complete to b$_{26.5}=20.0$, using a membership criterion based on the ...
Biviano, A. +6 more
core +2 more sources
Cervical Cancer Cells Use the CD95 and IL-2 Pathways to Promote Their Proliferation and Survival
BiomoleculesCervical cancer is a global health problem; therapies focused on eliminating tumour cells and strengthening different immunotherapies are in development.
Adriana Gutiérrez-Hoya +6 more
doaj +1 more source
Expression of apoptosis receptors on the cells in patients with herpes infections
RUDN Journal of Medicine, 2011 Expressions of CD95 receptors on the leukocytes in patients with HSV-1,2 infection as well as on the cervical cells was decreased (р < 0,05). No significant changes of expression of CD95 receptor in patients with cytomegalovirus were revealed.
Z F Kharaeva, А А Shevchenko
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