Results 81 to 90 of about 24,240 (208)
Acta Dermato-Venereologica, 2017 The aim of this 10-year monocentric prospective study was to determine a cut-off value of Fas/CD95 expression by peripheral blood CD4+ T lymphocytes in discriminating patients with mycosis fungoides from controls with cutaneous benign lymphocytic ...
Aurélie Du-Thanh +5 more
doaj +1 more source
Медицинская иммунология, 2014 CD95 (Fas/APO-1) antigen expression was studied on the surface of neutrophil granulocytes from cervical secretions. Sixty-five female patients with established Chlamydia infection were found to have an increased CD95+ antigen expression following basic ...
O. A. Giesinger, I. I. Dolgushin
doaj +1 more source
Abstract LB-341: CD95/FAS promotes tumorigenesis
, 2010 FAS/CD95 has been known as a typical death receptor that enhances cell apoptosis mainly in the immune system. Recent studies indicate that CD95 expression is rarely absent or down-regulated in solid tumors and CD95L, the cognate ligand that binds cell ...
Annika Hau +10 more
core +1 more source
eLife, 2016 Integrin activation is crucial for the regulation of leukocyte rolling, adhesion and trans-vessel migration during inflammation and occurs by engagement of myeloid cells through factors presented by inflamed vessels.
Liang Gao +5 more
doaj +1 more source
Activation of Anergic B Cells During Development of Autoimmunity
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT In healthy individuals, autoreactive B cells are normally silenced via central and peripheral tolerance mechanisms. In the periphery, when autoreactive B cells recognize self‐antigen via their B cell receptor (BCR) (signal 1) but do not receive T cell help (signal 2), they undergo the tolerance mechanism called anergy.
Mohammad Mansoor +2 more
wiley +1 more source
Molecular Mechanisms of Ceramide-Mediated CD95 Clustering
, 2001 The pattern of peptidoglycan (murein) segregation in Receptor clustering has been suggested as a crucial mechanism to initiate receptor signaling. Here we show that ceramide in sphingolipid-rich membrane rafts mediates clustering of CD95.
Schwarz, H., Grassmé , H., Gulbins, E.
core +1 more source
Cellular Physiology and Biochemistry, 2015 Background/Aims: Ursodeoxycholic acid, which in vivo is rapidly converted into its taurine conjugate, is frequently used for the treatment of cholestatic liver disease.
Annika Sommerfeld +2 more
doaj +1 more source
, 2008 Bone marrow transplantation (BMT) is commonly used for the treatment of severe haematological and immunological diseases. For instance, the autoimmune lymphoproliferative syndrome (ALPS) caused by a complete expression defect of CD95 (Fas, APO-1) can be ...
Müller, Stefan +11 more
core +1 more source
Glutathione Peroxidase-1 Protects from CD95-induced Apoptosis
, 2002 International audienceThrough the induction of apoptosis, CD95 plays a crucial role in the immune response and the elimination of cancer cells. Ligation of CD95 receptor activates a complex signaling network that appears to implicate the generation of ...
Gouazé, Valérie +13 more
core +1 more source
Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus. [PDF]
, 2010 We have addressed complex formation between the death domain (DD) of the death receptor CD95 (Fas/APO-1) with the DD of immediate adaptor protein FADD using nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and size-exclusion ...
Sankar, A +17 more
core +1 more source