Results 101 to 110 of about 1,696,937 (352)

Influence of the Clinical Status on Stress Reticulocytes, CD 36 and CD 49d of SSFA2 Homozygous Sickle Cell Patients Followed in Abidjan

Advances in Hematology, 2014
Background and Objectives. Interactions between sickle cells involving CD 49d, CD36, and the vascular endothelium may initiate vasoocclusion leading to acute painful episodes and multiple organ failure. Materials and Methods.
Duni Sawadogo, Aïssata Tolo-Dilkébié, Mahawa Sangaré, Nelly Aguéhoundé, Hermance Kassi, Toussaint Latte   +5 more
doaj   +1 more source

Tracking TCRß sequence clonotype expansions during antiviral therapy using high-throughput sequencing of the hypervariable region [PDF]

, 2016
To maintain a persistent infection viruses such as hepatitis C virus (HCV) employ a range of mechanisms that subvert protective T cell responses. The suppression of antigen-specific T cell responses by HCV hinders efforts to profile T cell responses ...
Arvind H Patel, Emma C Thomson, Gavin S Wilkie, John eMcLauchlan, Joseph eHughes, Mark W Robinson, Mark W Robinson, Peter R Mills, Rachael eSwann, Rachael eSwann, Stephen T Barclay   +10 more
core   +3 more sources

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Definition of Drosophila hemocyte subsets by cell-type specific antigens. [PDF]

, 2007
We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria.
Andó, István, Csorba, Kinga, Gateff, Elisabeth, Hultmark, Dan, Kurucz, Éva, Laurinyecz, Barbara, Márkus, Róbert, Vilmos, Péter, Váczi, Balázs, Zsámboki, János   +9 more
core   +1 more source

IL‐2 Free Expansion of T Cells with Immunofilaments

Advanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck, Lea Weiss, René Classens, Carl G. Figdor, Roel Hammink   +4 more
wiley   +1 more source

Disease-specific B cell clones are shared between patients with Crohn’s disease

Nature Communications
B cells have important functions in gut homeostasis, and dysregulated B cell populations are frequently observed in patients with inflammatory bowel diseases, including both ulcerative colitis (UC) and Crohn’s disease (CD). How these B cell perturbations
Prasanti Kotagiri, William M. Rae, Laura Bergamaschi, Diana Pombal, Ji-Yeun Lee, Nurulamin M. Noor, Raoul S. Sojwal, Samuel J. S. Rubin, Lukas W. Unger, Sofie H. Tolmeijer, Giulia Manferrari, Rachael J. M. Bashford-Rogers, David B. Bingham, Anton Stift, Stephan Rogalla, John Gubatan, James C. Lee, Kenneth G. C. Smith, Eoin F. McKinney, Scott D. Boyd, Paul A. Lyons   +20 more
doaj   +1 more source

Recombinant proteins as promising antigens applied to the immunodiagnosis of Chagas disease: a scoping review

Frontiers in Microbiology
Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is an important public health problem, occurring mainly in Latin America. The disease has a major social and economical effect, negatively impacting the life of the infected individuals, and
Carlos Ananias Aparecido Resende, Anna Júlia Ribeiro, Isadora Braga Gandra, Kamila Alves Silva, Lucas da Silva Lopes, Isabelle Caroline dos Santos Barcelos, Carolina Alves Petit Couto, Mariana Teixeira de Faria, Sabrina Paula Pereira, Sandra Rodrigues Xavier, Juliana Martins Machado, Mariana Campos da Paz, Ana Thereza Chaves, Eduardo Antônio Ferraz Coelho, Rodolfo Cordeiro Giunchetti, Miguel Angel Chávez-Fumagalli, Walderez Ornelas Dutra, Ana Alice Maia Gonçalves, Alexsandro Sobreira Galdino   +18 more
doaj   +1 more source

Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens.

Journal of Immunology, 1987
With the use of cultured human thymic epithelial (TE) cells, we have previously shown that thymocytes bind to TE cells in suspension in a rosette-forming assay.
L. Vollger, D. Tuck, T. Springer, B. Haynes, K. Singer   +4 more
semanticscholar   +1 more source

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

Advanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal, Majd Bisharat, Bassma Khamaisi, Krishanu Ghosal, Eid Nassar‐Marjiya, Qi Wu, Shadi Daoud, Idan Redenski, Samer Srouji, Shady Farah   +9 more
wiley   +1 more source

Diagnostic Accuracy of Tissue Transglutaminase and Combined Assay of Tissue Transglutaminase and Deamidated Gliadin Peptide in Children with Coeliac Disease: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Coeliac Disease (CD) is a systemic immune disorder caused by gluten in genetically susceptible individuals. A serological screening assay for CD has been designed to detect Immunoglobulin A (IgA) and IgG anti-tissue Transglutaminase (a-tTG)
Pankaj Kumar Yadav, Nisha Attri, Lalit Bharadia, Rajiv Kumar Bansal   +3 more
doaj   +1 more source