Differential response to microbial antigens by age of diagnosis in patients with Crohn's disease
Sandra M Quezada, Ankur Rustgi, Guruprasad D Jambaulikar, Raymond K Cross Department of Medicine, Division of Gastroenterology and Hepatology, University of Maryland School of Medicine, Baltimore, MD, USA Purpose: Fifteen percent of incident Crohn's
Quezada SM +3 more
doaj
Relative activities of distinct isotypes of murine and human major histocompatibility complex class II molecules in binding toxic shock syndrome toxin 1 and determination of CD antigens expressed on T cells generated upon stimulation by the toxin [PDF]
Takehiko Uchiyama +6 more
openalex +1 more source
A Potent and Effective Suicidal Listeria Vaccine Platform. [PDF]
Live-attenuated Listeria monocytogenes has shown encouraging potential as an immunotherapy platform in preclinical and clinical settings. However, additional safety measures will enable application across malignant and infectious diseases.
Benanti, Erin L +12 more
core
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng +6 more
wiley +1 more source
BackgroundExposure to antigens is crucial for child immune system development, aiding disease prevention and promoting infant health. Some common food antigen proteins are found in human breast milk.
Ángela Ruiz-Carnicer +5 more
doaj +1 more source
Monocytes as effector cells: Activated
Patrícia Leirião +2 more
openalex +1 more source
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
A highly sensitive e.l.i.s.a. for endopeptidase-24.11, the common acute-lymphoblastic-leukaemia antigen (CALLA, CD-10), applicable to material of porcine and human origin [PDF]
Steven Howell +4 more
openalex +1 more source
Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu +12 more
wiley +1 more source
344 Comparative assessment of product quality attributes associated with production of chimeric antigen receptor T cells expressing scFv CD-19 and scFv IL-13Ra2 by two manufacturing platforms [PDF]
SuJin Hwang +5 more
openalex +1 more source

