Results 231 to 240 of about 1,696,937 (352)

Detection of Gliadin-Activated CD4<sup>+</sup> T Cells Is a New Assay to Reveal Pathogenic Lymphocytes in Celiac Disease. [PDF]

open access: yesJ Cell Mol Med
Pisapia L   +9 more
europepmc   +1 more source

CLINICAL DIAGNOSTIC SIGNIFICANCE OF FAS/APO-1(CD-95)-ANTIGEN IN HIV- INFECTION

open access: hybrid, 2011
N. V. Moskaliova   +4 more
openalex   +2 more sources

Regulatory T cells constrain the TCR repertoire of antigen‐stimulated conventional CD 4 T cells [PDF]

open access: bronze, 2017
Martina Fontaine   +8 more
openalex   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang   +14 more
wiley   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

open access: yesAdvanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai   +15 more
wiley   +1 more source

Chronic obstructive pulmonary disease (COPD) and autoimmune diseases: unravelling complex interactions. [PDF]

open access: yesAnn Med
Ceasovschih A   +12 more
europepmc   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

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