Results 231 to 240 of about 1,680,486 (323)

TGF-11 pretreatment impairs the allostimulatory function of human bone marrow-derived antigen-presenting cells for both naive and primed T cells [PDF]

, 1996
Banas, RA, Bonham, CA, Fontes, P, Lu, L, Rao, AS, Starzl, TE, Thomson, AW, Zeevi, A   +7 more
core  

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

Advanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe, Larissa Ikelle, Mustafa S. Makia, Mashal Kakakhel, Muayyad R. Al‐Ubaidi, Muna I. Naash   +5 more
wiley   +1 more source

The time has come for a vaccine against Chagas disease. [PDF]

Lancet Reg Health Am
Teixeira SM, Burle-Caldas GA, Castro JT, Gazzinelli RT.   +3 more
europepmc   +1 more source

Precision Targeting of Myeloid Cells via Peptide Dendrimer‐Lipid Nanocarriers: A Novel Platform for Potent Cancer Immunotherapies

Advanced Science, EarlyView.
Precision targeting of the spleen and myeloid cells of the tumor microenvironment, with minimal hepatic delivery, is achieved using a modular peptide dendrimer‐lipid nanocarrier. Functional assays, transcriptomics, and rodent models validate this novel myeloid cell targeting nanocarrier as an efficacious immunotherapy, both as a cancer vaccine platform
Lawrence James Billing, Liam Martin, Tristan Henser‐Brownhill, Parisa Samangouei, Adam Leach, Phoebe Knight, Marina Apostolidou, Aaqib Ladak, Benita Nagel, Albert Kwok   +9 more
wiley   +1 more source

Enteral Nutrition in Pediatric Crohn's Disease: New Perspectives. [PDF]

Nutrients
Brindicci VF, Grieco R, Ruiz RG, Cardile S, Capriati T, Trovato CM, Bolasco G, Knafelz D, Bracci F, Alterio A, Ferretti F, Elia D, Spinetti E, Francavilla R, Diamanti A.   +14 more
europepmc   +1 more source

Conservation of unique cell-surface CD antigen mosaics in HIV-1–infected individuals [PDF]

, 2005
Adrian Woolfson, Justin Stebbing, Brian D. M. Tom, Kerryn Stoner, Walter R. Gilks, David P. Kreil, Stephen P. Mulligan, Larissa Belov, Jeremy S. Chrisp, Will Errington, Adrian Wildfire, Wendy N. Erber, Mark Bower, Brian Gazzard, Richard I. Christopherson, Mike Scott   +15 more
openalex   +1 more source

Differentiated T Lymphocytes and Cancer Cell Mitochondrial Metabolism to Enhance Radioimmunotherapy by a Biomimetic Nanozyme System

Advanced Science, EarlyView.
T cell membrane‐coated MgCO3/Fe‐CD nanozyme loaded with TEPP‐46 (TFMP) enhances breast cancer radioimmunotherapy by reprogramming mitochondrial metabolism in T cells and tumors. It targets PD‐L1, converts H2O2 into ROS, neutralizes acidity, and releases Mg2⁺/TEPP‐46 to boost T cell activation.
Hanyu Zhang, Yuhan Deng, Yantong Lu, Miao Wang, Kun Qiao, Zifan Yang, Shipeng Ning, Tong Liu   +7 more
wiley   +1 more source

Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn's disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn's disease. [PDF]

Front Immunol
Mahdy AKH, Schöpfel V, Huppertz-Hauss G, Perminow G, Tran F, Bang C, Hov JR, Bengtson MB, Ricanek P, Opheim R, Aabrekk TB, Detlie TE, Kristensen VA, Poyet M, Høivik ML, Franke A, ElAbd H.   +16 more
europepmc   +1 more source

Cancer Manipulates Adjacent Adipose Tissue to Exploit Fatty Acids via HIF‐1α/CCL2/PPARα Axis: A Metabolic Circuit to Support Tumor Progression

Advanced Science, EarlyView.
Cancer cells drive adjacent adipose tissue to release fatty acids by secreting CCL2, which activates PPARα‐dependent lipolysis. The resulting fatty acid influx amplifies HIF‐1α/CCL2 signaling, establishing a positive feedback loop that fuels tumor growth.
Jeong‐Eun Yun, Jieun Seo, Jiwon Koh, Seock‐Ah Im, Ki Yong Hong, Yeseon Son, Do‐Won Jeong, Junji Fukuda, Jong‐Wan Park, Yang‐Sook Chun   +9 more
wiley   +1 more source

Antineutrophil Cytoplasmic Autoantibodies Specific to Bactericidal/Permeability-Increasing Protein: A Cross-Road Between Prolonged Gram-Negative Bacterial Infections and Ulcerative Colitis/Primary Sclerosing Cholangitis. [PDF]

Diagnostics (Basel)
Jovanovic D, Miskovic R, Plavsic A, Radovic S, Nagorni-Obradovic L, Popovic D, Nikolic MM, Bonaci-Nikolic B.   +7 more
europepmc   +1 more source