Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice
Annals of Neurology, EarlyView.rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff +7 more
wiley +1 more source
Plasma proteins and the risk of inflammatory bowel diseases: A two-sample Mendelian randomization study. [PDF]
Medicine (Baltimore)Jiao Z, Li GG, Bai LS, Guo JZ, Pang LJ.
europepmc +1 more source
Metabolism‐Regulating Nanomedicines for Cancer Therapy
Advanced NanoBiomed Research, EarlyView.This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Immunohistopathological Analysis of Spongiosis Formation in Atopic Dermatitis Compared with Other Skin Diseases. [PDF]
Dermatopathology (Basel)Tanei R, Hasegawa Y.
europepmc +1 more source
Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro [PDF]
, 2015 Ashkan, Keyoumars +4 more
core +1 more source
Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease
Advanced NanoBiomed Research, EarlyView.Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang +5 more
wiley +1 more source
Ginsenoside F4 inhibits colorectal cancer progression by boosting dendritic cell maturation and remodeling the tumor microenvironment. [PDF]
World J Gastrointest OncolXie W +7 more
europepmc +1 more source
The definition of ABO factors in transplantation: Relation to other humoral antibody states [PDF]
, 1987 Banner, B +7 more
core
A Multiepitope‐Based Lateral Flow Assay for Leprosy Antibodies
Analysis &Sensing, EarlyView.An innovative lateral flow assay for leprosy diagnosis is based on gold nanoparticles and synthetic Mycobacterium leprae epitopes conjugated to keyhole limpet hemocyanin protein to enhance antibody detection. This strategy provides a rapid, accurate, and low‐cost approach for resource‐limited settings, enabling the early detection of infection. Leprosy
Cristiane Zocatelli‐Ribeiro +7 more
wiley +1 more source