Results 151 to 160 of about 81,267 (316)
Scientific Reports, 2016 The three canonical Rho GTPases RhoA, Rac1 and Cdc42 co-ordinate cytoskeletal dynamics. Recent studies indicate that all three Rho GTPases are activated at the leading edge of motile fibroblasts, where their activity fluctuates at subminute time and ...
Katrin Martin +5 more
semanticscholar +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2019 Xing-Hua Xiao,* Qi-Yuan Huang,* Xian-Ling Qian,* Jing Duan, Xue-Qiao Jiao, Long-Yuan Wu, Qing-Yun Huang, Jun Li, Xing-Ning Lai, Yu-Bo Shi, Li-Xia Xiong Department of Pathophysiology, Medical College, Nanchang University, Nanchang 330006, People’s ...
Xiao XH +10 more
doaj
Myelination: all about Rac n roll. [PDF]
, 2007 During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
core +2 more sources
Cell cycle entry triggers a switch between two modes of Cdc42 activation during yeast polarization
bioRxiv, 2017 Cell polarization underlies many cellular and organismal functions. The GTPase Cdc42 orchestrates polarization in many contexts. In budding yeast, polarization is associated with a focus of Cdc42•GTP which is thought to self sustain by recruiting a ...
K. Witte, D. Strickland, M. Glotzer
semanticscholar +1 more source
British Journal of Cancer, 2017 Background:The lethality and poor outcome of high-grade gliomas result from the tumour relentless invasion. miR-29a/b/c downexpressions contribute to several human tumourigenesis.
C. Shi +13 more
semanticscholar +1 more source
Limiting lumens: a new role for Cdc42 [PDF]
The Journal of Cell Biology, 2008 The formation of a single lumen is a necessary step in the formation of biological tubes. Different tissues have developed diverse ways to form their lumens. In this issue, Jaffe et al. (Jaffe, A.B., N. Kaji, J. Durgan, and A. Hall. 2008. J. Cell Biol. 183:625–633) report the development of an in vitro system for studying lumen formation that is driven
openaire +3 more sources
Nature Communications, 2017 Blood platelets are produced by large bone marrow (BM) precursor cells, megakaryocytes (MKs), which extend cytoplasmic protrusions (proplatelets) into BM sinusoids.
Sebastian Dütting +25 more
semanticscholar +1 more source
A role for Gic1 and Gic2 in Cdc42 polarization [PDF]
, 2018 AbstractThe conserved Rho-family GTPase Cdc42 is a master regulator of polarity establishment in many cell types. Cdc42 becomes activated and concentrated in a region of the cell cortex, and recruits a variety of effector proteins to that site.
Daniels, Christine N. +2 more
openaire +1 more source
Potential Adaptive Introgression From Dogs in Iberian Grey Wolves (Canis lupus)
Molecular Ecology, EarlyView.ABSTRACT Invading species along with increased anthropogenization may lead to hybridization events between wild species and closely related domesticates. As a consequence, wild species may carry introgressed alleles from domestic species, which is generally assumed to yield adverse effects in wild populations.
Carlos Sarabia +6 more
wiley +1 more source
Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]
, 2004 Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould +37 more
core +3 more sources