Results 171 to 180 of about 38,210 (217)

Overactivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells From Old Individuals Towards Senescent Fibroblasts. [PDF]

Aging Cell
Koroma AK, Singh K, Wang Y, Krug L, Haas P, Wlaschek M, Sakk V, Schuster T, Fürst D, Schrezenmeier H, Dheenadayalan RP, Stilgenbauer S, Walter L, Geiger H, Scharffetter-Kochanek K, Maity P.   +15 more
europepmc   +1 more source

Engineered interfaces in Rac1 and Cdc42 biosensors enhance sensitivity and reduce cell perturbation. [PDF]

Mol Biol Cell
Marston DJ, O'Shaughnessy EC, Jacobs TM, Huh J, Tsygankov D, Choi M, Ma X, Azoitei ML, Danuser G, Kuhlman B, Hahn KM.   +10 more
europepmc   +1 more source

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review). [PDF]

Oncol Rep
Daher A, Assi Z, Kanaan A, Al Khatib A, El Sibai M.   +4 more
europepmc   +1 more source

Does Ras/Rho Have Skin in the Game: The Importance of the Isoprenoid Biosynthesis Pathway in Merkel Cell Carcinoma Cell Lines. [PDF]

Cancers (Basel)
Blaha LN, Derosia NM, Neighbors JD, Hohl RJ.   +3 more
europepmc   +1 more source

Membrane curvature initiates Cdc42-FBP17-N-WASP clustering and actin nucleation. [PDF]

EMBO J
Zhu K, Guo X, Chandrasekaran A, Miao X, Rangamani P, Zhao W, Miao Y.   +6 more
europepmc   +1 more source

FABP7 controls radial glial scaffold stability during human cortical development. [PDF]

Proc Natl Acad Sci U S A
Wang Y, Zhang X, Ba R, Zhu Y, Yu H, Wang D, Chu C, Zhang X, Hong Y, Wu S, Zhu W, Xu M, Cheng Q, Zhao C, Han X, Liu Y.   +15 more
europepmc   +1 more source

Cholecystokinin A Receptor Knockdown Diminishes Colon Cancer Cell Invasive Potential via Modulation of Integrin/FAK, EMT, and uPA/uPAR/MMP2 Axis. [PDF]

Oncol Res
Lin CS, Hsu TW, Lee HL, Kao SH.
europepmc   +1 more source

Glabridin Inhibits Melanogenesis and Melanin Transfer via Wnt/β-Catenin Pathway and Rho Family GTPase-Mediated Dendritic Formation Suppression. [PDF]

Pharmaceuticals (Basel)
Li L, Zhang X, Tang G, Wu J, Huang Q.
europepmc   +1 more source

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Cdc42: Role in Cancer Management

Chemical Biology and Drug Design, 2015
Contribution of Cdc42, a member of Rho family, has been characterized for the beginning of variety of cellular responses including cellular transformation, cell division, cell invasion, migration, invadopodia formation, enzyme activity, filopodia formation, and cell polarity in cells. Deregulation of Cdc42 can alter the normal functioning of the cells,
Muhammad Ali, Mi Qadir
exaly   +3 more sources

NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42

Biomolecular NMR Assignments, 2007
Cdc42(T35A) is an active construct of Cdc42, a Ras GTPase involved in signal transduction, containing a single-point mutation in an important effector-binding region. We determined the backbone and side chain resonance assignments of (13)C,(15)N-labelled Cdc42(T35A) from E. coli.
Adams, Paul D., Oswald, Robert E.
openaire   +3 more sources