Results 181 to 190 of about 81,267 (316)
Journal of Cell Science, 2015 ABSTRACT Cdc42 plays a central role in establishing polarity in yeast and animals, yet how polarization of Cdc42 is achieved in response to spatial cues is poorly understood. Using live-cell imaging, we found distinct dynamics of Cdc42 polarization in haploid budding yeast in correlation with two temporal steps of the G1 phase.
Hay-Oak Park +4 more
openaire +4 more sources
Molecular Genetics &Genomic Medicine, Volume 13, Issue 5, May 2025.Phenotypic features of the 1p36 deletion syndrome in adults and children have been identified; however, due to the limitations of phenotypic identification in prenatal diagnosis, these features have not yet been described in prenatal cases. The 1p36 deletions are increasingly found by chance during prenatal testing using a single nucleotide ...
Meiying Cai +6 more
wiley +1 more source
Biology Open, 2015 Hair cells of the organ of Corti (OC) of the cochlea exhibit distinct planar polarity, both at the tissue and cellular level. Planar polarity at tissue level is manifested as uniform orientation of the hair cell stereociliary bundles. Hair cell intrinsic
Anna Kirjavainen +3 more
doaj +1 more source
Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway
Cell Death and Disease, 2016 Podocyte apoptosis is a major mechanism that leads to proteinuria in many chronic kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood.
Zhijie Huang +19 more
semanticscholar +1 more source
Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis. [PDF]
, 1996 Anne M. Murphy, Denise J. Montell
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The FEBS Journal, Volume 292, Issue 9, Page 2173-2188, May 2025.Mitogen‐activated protein kinases (MAPKs) regulate various cellular processes, including proliferation, differentiation, and motility. Alterations in these signalling pathways can lead to various diseases, including cancer. The atypical MAPKs ERK3 (MAPK6), ERK4 (MAPK4), ERK7/8 (MAPK15) and NLK have long been neglected in kinomic studies.
Katrin Dahm +4 more
wiley +1 more source
Multiple Signal Transduction Pathways Regulate TNF-Induced Actin Reorganization in Macrophages: Inhibition of Cdc42-Mediated Filopodium Formation by TNF [PDF]
, 1999 Maikel P. Peppelenbosch +7 more
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Molecular Microbiology, Volume 123, Issue 5, Page 420-432, May 2025.Proposed model in which human miR‐6762‐5p expression activates RhoA to promote Shigella flexneri dissemination: During the late phase of infection, miR‐6762‐5p is expressed from its host gene TPCN1. This leads to RhoA activation and thus stress fiber formation.
Caroline Reisacher +6 more
wiley +1 more source
International Journal of Endocrinology, 2019 Background. Diabetes is a progressive metabolic disease characterized by hyperglycemia. Functional impairment of islet β cells can occur to varying degrees.
Jing Duan +9 more
doaj +1 more source
Tyrosine phosphorylation of the Wiskott‐Aldrich Syndrome protein by Lyn and Btk is regulated by CDC42 [PDF]
, 1998 Rodolphe Guinamard +4 more
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