Supplementary 4: Optimal conditions for Cdc42 siRNA mediated knockdown.
Alyssa Biondo, Patricio Meneses
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Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy
Background Immune checkpoint inhibitors (ICIs) have achieved great success; however, a subset of patients exhibits no response. Consequently, there is a critical need for reliable predictive biomarkers.
Kun Wang +9 more
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Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells [PDF]
Toshihiko Suzuki +7 more
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Developmental defects of enamel are common due to genetic and environmental factors before and after birth. Cdc42, a Rho family small GTPase, regulates prenatal tooth development in mice.
Jinxuan Zheng +14 more
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MICAL‐L2 potentiates Cdc42‐dependent EGFR stability and promotes gastric cancer cell migration [PDF]
Pengxiang Min +11 more
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Specific Patterns of Cdc42 Activity Are Related to Distinct Elements of T Cell Polarization [PDF]
Irina Tskvitaria‐Fuller +5 more
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Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2 [PDF]
Tomoyuki Sumi +3 more
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Dynamic cofilin phosphorylation in the control of lamellipodial actin homeostasis [PDF]
During animal cell chemotaxis, signalling at the plasma membrane induces actin polymerisation to drive forward cell movement. Since the cellular pool of actin is limited, efficient protrusion formation also requires the coordinated disassembly of pre ...
Baum, B +4 more
core
Nicotine Promotes Mammary Tumor Migration via a Signaling Cascade Involving Protein Kinase C and cdc42 [PDF]
Jinjin Guo +6 more
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