Results 21 to 30 of about 393 (141)

Identification and validation of hub differential genes in pulmonary sarcoidosis. [PDF]

Front Immunol
A total of 138 cDEGs were screened from mediastinal lymph nodes and peripheral whole blood. Among them, 6 hub cDEGs including CTSS, CYBB, FPR2, MNDA, TLR1 and TLR8 with elevated degree and betweenness levels were illustrated in protein-protein ...
Yao Q, Min K, Zhao M, Chen X, Weng D, Zhou Y.   +5 more
europepmc   +2 more sources

Cancer-associated fibroblast related gene signature in Helicobacter pylori-based subtypes of gastric carcinoma for prognosis and tumor microenvironment estimation in silico analysis

Frontiers in Medicine, 2023
IntroductionGastric cancer (GC) remains the major constituent of cancer-related deaths and a global public health challenge with a high incidence rate.
Ruofan Xu, Ruofan Xu, Le Yang, Le Yang, Zhewen Zhang, Zhewen Zhang, Yuxuan Liao, Yuxuan Liao, Yao Yu, Yao Yu, Dawei Zhou, Dawei Zhou, Jiahao Li, Jiahao Li, Haoyu Guan, Haoyu Guan, Wei Xiao   +16 more
doaj   +1 more source

Decoding core genes and intercellular communication in osteosarcoma: bioinformatic investigation and immune cell profiling for diagnostic and therapeutic insights.

Discov Oncol
The study focusing on developing an artificial neural network (ANN) model in accordance with genetic characteristics of osteosarcoma (OS) to accurately speculate OS cases.
Rong K, Kuang H, Ou L, Fang R, Kuang J, Yang H.   +5 more
europepmc   +2 more sources

Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

BMC Medical Genomics, 2023
Background Detection of appropriate receptor proteins and drug agents are equally important in the case of drug discovery and development for any disease.
Md Abu Horaira, Md. Ariful Islam, Md. Kaderi Kibria, Md. Jahangir Alam, Syed Rashel Kabir, Md. Nurul Haque Mollah   +5 more
doaj   +1 more source

In-Silico discovery of Pediatric Acute-Myeloid-Leukemia (pAML) causing druggable molecular signatures highlighting their pathogenetic processes and therapeutic agents through single-cell RNA-Seq profile analysis. [PDF]

PLoS One
Pediatric acute-myeloid-leukemia (pAML) is an aggressive malignancy and the second most common blood cancer in children. In spite of significant advances in the frontline therapeutic approaches, approximately 50% of pAML patients show poor prognosis and ...
Ahmed MF, Al Noman M, Ahmed MF, Latif MA, Pappu MAA, Islam MS, Hossain MS, Hossen MB, Faysal MF, Hasan MM, Mollah MNH.   +10 more
europepmc   +2 more sources

Comparison of Grounding Grid Parameters Between Copper and Galvanized Flat Steel [PDF]

E3S Web of Conferences, 2021
In the intelligent substation, the shell of the secondary equipment is connected to the ground grid locally. When the short circuit fault current is injected into the grounding grid to cause the ground potential rise, the potential difference between the
Yu Yue, Li Yanjun, Wang Dehong, Du Rongtian, Jiao Chongqing, Sun Jiwei   +5 more
doaj   +1 more source

Tower impulse grounding resistance measurement based on multiple frequency impedance

IET Generation, Transmission &Distribution, Volume 17, Issue 15, Page 3488-3500, August 2023., 2023
This paper proposes a novel impulse grounding resistance measurement method based on multiple frequency impedance, which helps accurate and convenient evaluation of impulse grounding performance in practical environments and lightning protection performance of the power transmission systems.
Yihua Dan, Ruixuan Zhang, Yongye Wu, Yiqiao Li, Xuement Wang, Jian Yang   +5 more
wiley   +1 more source

Integrative Proteo-Genomic Analysis for Recurrent Survival Prognosis in Colon Adenocarcinoma

Frontiers in Oncology, 2022
BackgroundThe survival prognosis is the hallmark of cancer progression. Here, we aimed to develop a recurrence-related gene signature to predict the prognosis of colon adenocarcinoma (COAD).MethodsThe proteomic data from the Clinical Proteomic Tumor ...
FeiYan Ai, FeiYan Ai, Wenhao Wang, Shaojun Liu, Decai Zhang, Decai Zhang, Zhenyu Yang, Fen Liu, Fen Liu   +8 more
doaj   +1 more source

Optimal sizing and operation of hybrid energy storage systems in co‐phase traction power supply system considering battery degradation

IET Generation, Transmission &Distribution, Volume 17, Issue 9, Page 2038-2054, May 2023., 2023
A co‐phase power supply system with hybrid energy storage system (HESS) for electrified railway is studied. A bi‐level optimization model considering battery degradation to obtain both optimal sizing and operation of HESS is proposed. The proposed model includes a novel real‐time energy management scheme (EMS); the lower level is built as a dynamic ...
Shengfu Gao, Qunzhan Li, Xiaohong Huang, Qingan Ma, Wei Liu, Sida Tang   +5 more
wiley   +1 more source

Enhanced insulin‐regulated phagocytic activities support extreme health span and longevity in multiple populations

Aging Cell, Volume 22, Issue 5, May 2023., 2023
The immune system plays a central role in aging. The findings illustrated that the innate immune system plays critical roles in shaping extreme health span and longevity. Monocytes from long‐lived individuals reveal enhanced life‐cycles and a M2‐like phenotype, which are associated with an insulin‐driven immune‐metabolic network that supports multiple ...
Deng Wu, Xiaoman Bi, Peihu Li, Dahua Xu, Jianmin Qiu, Kongning Li, Shaojiang Zheng, Kim Hei‐Man Chow   +7 more
wiley   +1 more source