Cancer-associated fibroblast related gene signature in Helicobacter pylori-based subtypes of gastric carcinoma for prognosis and tumor microenvironment estimation in silico analysis [PDF]
IntroductionGastric cancer (GC) remains the major constituent of cancer-related deaths and a global public health challenge with a high incidence rate.
Ruofan Xu +16 more
doaj +2 more sources
Integrated transcriptomics unveils mitochondrial oxidative phosphorylation dysfunction as a shared mechanism in sarcopenia and obesity [PDF]
Sarcopenia and obesity, two prevalent metabolic disorders in aging populations, often coexist and share overlapping pathophysiological mechanisms, yet the molecular mechanisms underlying their comorbidity remain elusive.
Ruixuan Yu +6 more
doaj +2 more sources
THE Simulation Study of DC Grounding Electrode Based on CDEGS and ANSYS
When the UHVDC project was put into operation, grounding electrode grounding current may affect the transformer in the substation near the pole, it will cause transformer DC bias saturation, which leads to higher transformer temperature rise, too high harmonic and reactive power consumption, which will cause transformer damage or power grid blackout ...
Chenglian Ma +4 more
exaly +2 more sources
Integrative analysis identifies shared therapeutic pathways in thyroid eye disease and diabetes mellitus [PDF]
Thyroid eye disease (TED) and diabetes mellitus (DM) cause vision loss, with DM aggravating TED. In this study, we aimed to explore the mechanisms of this interaction, and therefore, analyzed gene expression data from representative TED and DM datasets ...
Yifei Wang, Hui Li
doaj +2 more sources
Evaluation of steady-state ground resistance by field measurement and CDEGS computation [PDF]
In addition to the soil resistivity and size of the grounding system, grounding system configuration can influence the steady-state resistance (RDC) of a grounding system. The RDC of four to six configurations in three distinct soil conditions (sites 1 to 3) is measured using the fall-of-potential method and computed using the current distribution ...
Usman Muhammad +4 more
openaire +3 more sources
Abstract It is of importance to assess the electromagnetic influcence of HVDC converter station on buried metal facilities of AC substations, fossil-fuel plants, windfarms and pipelines. Electromagnetic interference model was established based on the experimental measurement of soil resistivity and actual physical location.
Xiaosheng Cheng +5 more
exaly +2 more sources
In-Silico discovery of Pediatric Acute-Myeloid-Leukemia (pAML) causing druggable molecular signatures highlighting their pathogenetic processes and therapeutic agents through single-cell RNA-Seq profile analysis. [PDF]
Pediatric acute-myeloid-leukemia (pAML) is an aggressive malignancy and the second most common blood cancer in children. In spite of significant advances in the frontline therapeutic approaches, approximately 50% of pAML patients show poor prognosis and ...
Md Foysal Ahmed +10 more
doaj +2 more sources
Screening of common genomic biomarkers to explore common drugs for the treatment of pancreatic and kidney cancers with type-2 diabetes through bioinformatics analysis [PDF]
Type 2 diabetes (T2D) is a crucial risk factor for both pancreatic cancer (PC) and kidney cancer (KC). However, effective common drugs for treating PC and/or KC patients who are also suffering from T2D are currently lacking, despite the probability of ...
Alvira Ajadee +5 more
doaj +2 more sources
Insights into cucumber (Cucumis sativus) genetics: Genome-wide discovery and computational analysis of the Calreticulin Domain-Encoding gene (CDEG) family [PDF]
Cucumber is an essential vegetable crop throughout the world. Cucumber development is vital for accomplishing both quality and productivity requirements. Meanwhile, numerous factors have resulted in substantial cucumber losses. However, the calreticulin domain-encoding genes (CDEGs) in cucumber were not well-characterized and had little function.
Pravej Alam, Thamer Albalawi
openaire +3 more sources
The Potential Difference Characteristics between Two Points on Grounding Grid of Substation
With the intelligentization upgrade of power substations, a large number of secondary equipment are deployed dispersedly nearby the high-voltage primary equipment. The enclosures of these secondary devices are electrically connected to the grounding grid
Yonghong WANG +6 more
doaj +1 more source

