Results 21 to 30 of about 1,371 (186)

Insights into cucumber (Cucumis sativus) genetics: Genome-wide discovery and computational analysis of the Calreticulin Domain-Encoding gene (CDEG) family. [PDF]

Saudi J Biol Sci
Cucumber is an essential vegetable crop throughout the world. Cucumber development is vital for accomplishing both quality and productivity requirements. Meanwhile, numerous factors have resulted in substantial cucumber losses. However, the calreticulin domain-encoding genes (CDEGs) in cucumber were not well-characterized and had little function.
Alam P, Albalawi T.
europepmc   +3 more sources

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease. [PDF]

Adv Sci (Weinh)
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Lu H, Zhu Y, Wang X, Wu Z, Xu Z, Chen R, Guo Y.   +6 more
europepmc   +2 more sources

Discovery of Essential Genes as Possible Targets for Prostate Cancer Drug Development. [PDF]

Int J Genomics
Prostate cancer (PCa) is a major malignancy affecting men and is a significant contributor to global male mortality. Over the past decade, several new treatments for advanced PCa have been approved; however, opportunities remain for the development of novel therapeutic strategies.
Arman MAU, Reza MS, Alamin MH, Maya TA, Hossain MT.   +4 more
europepmc   +2 more sources

The Potential Difference Characteristics between Two Points on Grounding Grid of Substation

Zhongguo dianli, 2021
With the intelligentization upgrade of power substations, a large number of secondary equipment are deployed dispersedly nearby the high-voltage primary equipment. The enclosures of these secondary devices are electrically connected to the grounding grid
Yonghong WANG, Chongqing JIAO, Bing XIAO, Anqi GUO, Guizhong QIU, Lipeng BI, Keqiang XU   +6 more
doaj   +1 more source

Effect of grounding grid of power transmission line on buried pipeline under short circuit fault

You-qi chuyun, 2021
In order to study the electromagnetic interference of the short-circuit current of grounding point when power transmission line is in fault operation, a model for grounding grid of transmission line towers and buried pipelines was established with the ...
Shaojie WANG, Yuanchao HU, Wenlong ZHAO, Xun LI, Dong JING   +4 more
doaj   +1 more source

Identification of Differentially Expressed Genes Reveal Conserved Mechanisms in the Rice-Magnaporthe oryzae Interaction

Frontiers in Plant Science, 2022
Magnaporthe oryzae causes rice blast disease and is responsible for major losses in rice production worldwide. Although numerous studies have focused on the interactions between Oryza sativa and M. oryzae, to date, the conserved mechanisms remain in part
Dong Liang, Zhongqiang Qi, Yan Du, Junjie Yu, Mina Yu, Rongsheng Zhang, Huijuan Cao, Xiayan Pan, Junqing Qiao, Tianqiao Song, Youzhou Liu, Zhiyi Chen, Yongfeng Liu   +12 more
doaj   +1 more source

Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

BMC Medical Genomics, 2023
Background Detection of appropriate receptor proteins and drug agents are equally important in the case of drug discovery and development for any disease.
Md Abu Horaira, Md. Ariful Islam, Md. Kaderi Kibria, Md. Jahangir Alam, Syed Rashel Kabir, Md. Nurul Haque Mollah   +5 more
doaj   +1 more source

Comparison of Grounding Grid Parameters Between Copper and Galvanized Flat Steel [PDF]

E3S Web of Conferences, 2021
In the intelligent substation, the shell of the secondary equipment is connected to the ground grid locally. When the short circuit fault current is injected into the grounding grid to cause the ground potential rise, the potential difference between the
Yu Yue, Li Yanjun, Wang Dehong, Du Rongtian, Jiao Chongqing, Sun Jiwei   +5 more
doaj   +1 more source

Integrative Proteo-Genomic Analysis for Recurrent Survival Prognosis in Colon Adenocarcinoma

Frontiers in Oncology, 2022
BackgroundThe survival prognosis is the hallmark of cancer progression. Here, we aimed to develop a recurrence-related gene signature to predict the prognosis of colon adenocarcinoma (COAD).MethodsThe proteomic data from the Clinical Proteomic Tumor ...
FeiYan Ai, FeiYan Ai, Wenhao Wang, Shaojun Liu, Decai Zhang, Decai Zhang, Zhenyu Yang, Fen Liu, Fen Liu   +8 more
doaj   +1 more source

Robust Identification of Differential Gene Expression Patterns from Multiple Transcriptomics Datasets for Early Diagnosis, Prognosis, and Therapies for Breast Cancer

Medicina, 2023
Background and Objectives: Breast cancer (BC) is one of the major causes of cancer-related death in women globally. Proper identification of BC-causing hub genes (HubGs) for prognosis, diagnosis, and therapies at an earlier stage may reduce such death ...
Khanis Farhana Tuly, Md. Bayazid Hossen, Md. Ariful Islam, Md. Kaderi Kibria, Md. Shahin Alam, Md. Harun-Or-Roshid, Anjuman Ara Begum, Sohel Hasan, Rashidul Alam Mahumud, Md. Nurul Haque Mollah   +9 more
doaj   +1 more source