Results 281 to 290 of about 138,770 (367)

Functional Analysis of the PI3K/AKT/mTOR Pathway Inhibitor, Gedatolisib, Plus Fulvestrant with and Without Palbociclib in Breast Cancer Models. [PDF]

Int J Mol Sci
Broege A, Rossetti S, Sen A, De La Forest A, Davis L, Seibel M, Menon AS, Stokke S, Macaulay A, Molden J, Laing L.   +10 more
europepmc   +1 more source

Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1

Cell, 1999
J. Harbour, Robin X. Luo, Angeline Dei Santi, A. Postigo, D. Dean   +4 more
semanticscholar   +1 more source

Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Epigallocatechin gallate (EGCG), a bioactive compound abundantly exists in green tea and grapes with strong antioxidant activity and anticancer potential is a suitable approach to reduce the cancer burden. The invitro and invivo anticancer studies of EGCG proved anticancer and anti‐tumor effect through modulation of cancer signaling pathways, reduction
Ahmad Mujtaba Noman, Muhammad Tauseef Sultan, Aimen Mazhar, Iqra Baig, Jawaria Javaid, Muzzamal Hussain, Muhammad Imran, Suliman A. Alsagaby, Waleed Al Abdulmonem, Ahmed Mujtaba, Tadesse Fenta Yehuala, Mohammed M. Ghoneim, Ehab M. Mostafa, Mohamed A. Abdelgawad   +13 more
wiley   +1 more source

Control of CDK activity and the cell cycle by CKS proteins

Curran JF, Basu S, Auchynnikava T, Nurse P.   +3 more
europepmc   +1 more source

Current progress in targeting mitotic kinases in PDAC. [PDF]

RSC Med Chem
Barlow TMA, Rooman I, Ballet S.
europepmc   +1 more source

Functional Inactivation of the Retinoblastoma Protein Requires Sequential Modification by at Least Two Distinct Cyclin-cdk Complexes

Molecular and Cellular Biology, 1998
A. Lundberg, R. Weinberg
semanticscholar   +1 more source

Late‐Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4‐Induced Molecular Signature

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 4, August 2025.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is a fatal X‐linked recessive disease due to loss‐of‐function variants in the DYSTROPHIN gene. DMD‐related skeletal muscle wasting is typified by an aberrant immune response involving upregulation of the TGFβ family of cytokines, like TGFβ1 and BMP4.
Hanna Sothers, Xianzhen Hu, David K. Crossman, Ying Si, Matthew S. Alexander, Merry‐Lynn N. McDonald, Peter H. King, Michael A. Lopez   +7 more
wiley   +1 more source

Enhancing HCV NS3 Inhibitor Classification with Optimized Molecular Fingerprints Using Random Forest. [PDF]

Int J Mol Sci
Atasever S.
europepmc   +1 more source

Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells

, 2002
Min‐Hsiung Pan
openalex   +1 more source

CDK Inhibitors

, 2007
Wang, Hong, Zhou, Yongming, Acosta, Juan Antonio Torres, Fowke, Larry   +3 more
openaire   +1 more source