Results 311 to 320 of about 138,770 (367)

Cyclin-dependent kinases as mediators of aberrant transcription in prostate cancer. [PDF]

Transl Oncol
Rahman R, Selth LA.
europepmc   +1 more source

Naringenin Inhibits Cellular Proliferation, Arrests Cell Cycle and Induces Pro‐Apoptotic Autophagy in MCF‐7 Breast Cancer Cells

Journal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT The global incidence of breast cancer has significantly increased, highlighting the need for novel therapeutic strategies. Current treatment options are often limited by drug resistance and adverse effects, necessitating the exploration of alternative compounds.
Suhail Ahmad Mir, Basharat Ahmad Bhat, Priti S. Shenoy, Laraibah Hamid, Nasir Nisar, Ashraf Dar, Pritha Ray, Ghulam Nabi Bader   +7 more
wiley   +1 more source

Dinaciclib Interrupts Cell Cycle and Induces Apoptosis in Oral Squamous Cell Carcinoma: Mechanistic Insights and Therapeutic Potential. [PDF]

Int J Mol Sci
Oner M, Cheng YC, Soong SW, Cheng PT, Wang YH, Yang SF, Tsai SC, Lin H.   +7 more
europepmc   +1 more source

The TP53 tumor suppressor gene: From molecular biology to clinical investigations

Journal of Internal Medicine, Volume 298, Issue 2, Page 78-96, August 2025.
Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley   +1 more source

Targeting CDK4/6 in Cancer: Molecular Docking and Cytotoxic Evaluation of <i>Thottea siliquosa</i> Root Extract. [PDF]

Biomedicines
Elakkiya MR, Krishnasreya M, Tharani S, Arun M, Vijayalakshmi L, Lim J, Ghfar AA, Chithradevi B.   +7 more
europepmc   +1 more source

Chemical inducers of proximity: precision tools for apoptosis in transcriptional regulation. [PDF]

Signal Transduct Target Ther
Huang K.
europepmc   +1 more source

Metabolic engineering of stomatal precursor cells enhances photosynthetic water‐use efficiency and vegetative growth under water‐deficit conditions in Arabidopsis thaliana

Plant Biotechnology Journal, Volume 23, Issue 8, Page 3177-3194, August 2025.
Summary Stomata are epidermal pores that control the exchange of gaseous CO2 and H2O between plants and their environment. Modulating stomatal density can alter this exchange and thus presents a viable target for engineering improved crop productivity and climate resilience.
Jacques W. Bouvier, Steven Kelly
wiley   +1 more source

Polyploid giant cancer cells and tumor budding: translation from basic research to clinical application. [PDF]

Front Oncol
Huang P, Wu R, Yang Z, Li Y, Fei F, Yu Y.   +5 more
europepmc   +1 more source

The ABAP1 interacting protein 10 (AIP10) exerts a dual role in the cell cycle and primary metabolism pathways in Arabidopis thaliana

The Plant Journal, Volume 123, Issue 3, August 2025.
Significance Statement Plants regulate cell division to adapt growth to environmental changes. In Arabidopsis thaliana, AIP10 acts as a hub linking the cell cycle to primary metabolism. Its silencing increases cell division rates, enhances carbon fixation, and boosts metabolite accumulation, driving improved development and productivity. SUMMARY Plants
Patrícia Montessoro, Joaquin Felipe Roca Paixão, Carinne N. M. Costa, Laura Ducatti, Letícia Perdigão Grangeiro, Vivian Ruivo, Adriana Flores Fusaro, Helkin F. Ballesteros, Vanessa Iurif, Luiz Mors Cabral, Jelmir Craveiro de Andrade, Leticia Tessaro, Wallace de Paula Bernado, Fernanda Silva Coelho, Bruna Gino de Araújo‐Lopes, Janice de Almeida Engler, Jérémie Bazin, Eliemar Campostrini, Carlos Adam Conte‐Junior, Adriana Silva Hemerly   +19 more
wiley   +1 more source