Results 181 to 190 of about 405,232 (337)

Subtractive Hybridization and Construction of cDNA Libraries [PDF]

, 2003
Bruce Blumberg, Juan Carlos Izpisua Belmonte   +1 more
openaire   +4 more sources

Activation of HTR2B Suppresses Osteosarcoma Progression through the STAT1‐NLRP3 Inflammasome Pathway and Promotes OASL1+ Macrophage Production to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang, Jiazhuang Zhu, Jianping Hu, Xingkai Wang, Xiaolong Ma, Enjie Xu, Kunpeng Zhu, Chunlin Zhang   +7 more
wiley   +1 more source

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes [PDF]

, 2000
Piero Carninci, Yûkô Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki   +9 more
openalex   +1 more source

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase

Advanced Science, EarlyView.
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo, Jiechun Lin, Qiwen Ren, Hao Sun, Yanhua Wu, Haofei Ge, Xiaolan Wu, Lihui Lin, Lining Liang, Changpeng Li, He Liu, Yuangbang Mai, Shilong Chu, Jiadong Liu, Jing Liu, Jiekai Chen, Duanqing Pei, Hui Zheng   +17 more
wiley   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

Advanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang, Jiahao Cao, Siqi Zhang, Hongli Chen, Xuebing Yu, Xinli Wang, Tianji Wang, Wei Cao, Wengang Dong, Xinsen Lin, Jia Li, Wei Lei, Yafei Feng   +12 more
wiley   +1 more source

Construction of a cDNA library and preliminary analysis of the expressed sequence tags of the earthworm Eisenia fetida (Savigny, 1826). [PDF]

Mol Med Rep, 2019
Liu C, Wang X, Tian JB, Ma PY, Meng FX, Zhang Q, Yu BF, Guo R, Liu ZZ, Wang HL, Xie J, Cheng NL, Wang JH, Niu B, Sun GQ.   +14 more
europepmc   +1 more source

Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2)

, 1991
Neeraj Agarwal, Chih‐Lin Hsieh, Diane Sills, Manju Swaroop, Bhupesh B. Desai, Uta Francke, Anand Swaroop   +6 more
openalex   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

Generation and characterization of expressed sequence tags (ESTs) from coralloid root cDNA library of Cycas debaoensis. [PDF]

Plant Divers, 2018
Wang Y, Li N, Chen T, Gong Y.
europepmc   +1 more source

Analysis of Epstein--Barr virus gene transcription in lymphoma induced by the virus in the cottontop tamarin by construction of a cDNA library with RNA extracted from a tumour biopsy

, 1993
Chang Zhang, P. Lowrey, S. Finerty, Andrew Morgan   +3 more
openalex   +1 more source