Results 221 to 230 of about 149,367 (278)

Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease. [PDF]

Alzheimers Dement
Schultz SA, Rao Y, Liu L, Ostaszewski B, Anderson AK, Yau WW, Shirzadi Z, Gordon BA, Hassenstab J, Morris JC, Perrin RJ, Allegri RF, Barthélemy NR, Fox N, Day GS, Jucker M, Levey AI, Levin J, Mori H, Salloway S, Schofield P, McDade E, Sperling RA, Bateman RJ, Selkoe DJ, Chhatwal JP, and the Dominantly Inherited Alzheimer's Network.   +26 more
europepmc   +1 more source

High‐throughput single‐cell DNA methylation and chromatin accessibility co‐profiling with SpliCOOL‐seq

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
SpliCOOL‐seq achieves high‐throughput single‐cell co‐profiling of DNA methylation and chromatin accessibility. DNMT inhibitors caused cancer cell demethylation with divergent patterns. SpliCOOL‐seq enables the discovery of genes related to LUAD tumorigenesis. Ageing and LUAD tumorigenesis may share similar epigenetic alterations.
Qingmei Shen, Enze Deng, Ling Luo, Jingna Zhang, Qifeng Yang, Dan Su, Xiaoying Fan   +6 more
wiley   +1 more source

Increased Risk of Transition to Institutional Care Among Community‐Dwelling Older Adults With Cognitive Frailty: A Competing Risks Survival Analysis

International Journal of Geriatric Psychiatry, Volume 41, Issue 2, February 2026.
ABSTRACT Background Cognitive frailty (CF) is the coexistence of physical frailty and cognitive impairment. Transition to institutional care (TIC) refers to the move from home to a long‐term care institution and represents a major change in living arrangement and care needs among older adults.
Jinwei Bian, Zi Chen, Daniel Yee Tak Fong, Edmond Pui Hang Choi, Pui Hing Chau   +4 more
wiley   +1 more source

Long-Term Effects of Mobile-Based Metamemory Cognitive Training in Older Adults With Mild Cognitive Impairment: 15-Month Prospective Single-Arm Longitudinal Study. [PDF]

JMIR Aging
Lim JI, Byeon Y, Kang S, Kim H, Kim KY, Stenzel L, Jeon SY, Lee JY.   +7 more
europepmc   +1 more source

CDR Run 1 Report

Designed MMIC’s and packages will be scrutinized from the level of MMIC schematics, layout and simulation performance. The evaluation of simulated performance includes consideration of involved models, small-signal S parameters simulations, Harmonic balance simulations, and EM simulations of passives. The report will include bare-die performance, and a
openaire   +1 more source

Molecular and Transcriptional Signatures of Gray Matter Volume Alterations Associated With Depressive Symptoms in Mild Cognitive Impairment

Human Brain Mapping, Volume 47, Issue 2, February 1, 2026.
Morphological alterations related to depressive symptoms in mild cognitive impairment were primarily involved in emotion and affective processing, showing strong correspondence with serotonergic, dopaminergic, and GABAergic systems and enrichment of genes associated with synaptic function and excitatory neurons.
Hu Xu, Yang Li, Chensi Li, Fenglin Xu, Yun Liu, Kehan Yan, Shiyi Chen, Wenxiu Song, Yifeng Luo, Yuefeng Li   +9 more
wiley   +1 more source

Correction: Almutairi et al. The Expression Patterns of Human Cancer-Testis Genes Are Induced through Epigenetic Drugs in Colon Cancer Cells. Pharmaceuticals 2022, 15, 1319. [PDF]

Pharmaceuticals (Basel)
Almutairi MH, Alrubie TM, Almutairi BO, Alamri AM, Alrefaei AF, Arafah MM, Alanazi M, Semlali A.   +7 more
europepmc   +1 more source

Response of Tropical Cyclone‐Related Precipitation During Boreal Summer Season Over East Asia to Pseudo‐Global‐Warming Climates

International Journal of Climatology, Volume 46, Issue 2, February 2026.
Difference of monthly mean TC‐related precipitation (mm) during JAS over the EA between the SSP245 run and the CTL run in (a) TC core precipitation (TCP) + TC remote precipitation (TRP), (b) TCP and (c) TRP. ABSTRACT Climate change has fundamentally altered tropical cyclone (TC) characteristics globally, with TC‐related precipitation emerging as a ...
Jiwei Wu, Ryuichi Kawamura, Takashi Mochizuki, Tetsuya Kawano   +3 more
wiley   +1 more source

Early axonal degeneration linked to clinical decline in Alzheimer's disease progression revealed with diffusion MRI. [PDF]

J Clin Invest
Gong Z, Laporte JP, Guo AY, Bilgel M, Bae J, Fox NY, de Rouen A, Zhang N, Taranath A, de Cabo R, Egan JM, Ferrucci L, Bouhrara M, Alzheimer’s Disease Neuroimaging Initiative.   +13 more
europepmc   +1 more source