Results 111 to 120 of about 10,239 (195)

Targeted Inhibition of CD74 + Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

open access: yesAdvanced Science
Abstract Synovial inflammation represents a hallmark pathological process in osteoarthritis (OA), yet the cellular drivers orchestrating this response remain incompletely defined. Through single‐cell transcriptomic profiling of human OA synovial tissues, a distinct subset of CD74⁺ macrophages is identified that ...
Rui Peng   +15 more
openaire   +2 more sources

Expression characteristics of lipid metabolism-related genes and correlative immune infiltration landscape in acute myocardial infarction

open access: yesScientific Reports
Lipid metabolism is an important part of the heart's energy supply. The expression pattern and molecular mechanism of lipid metabolism-related genes (LMRGs) in acute myocardial infarction (AMI) are still unclear, and the link between lipid metabolism and
Jiahe Wu   +9 more
doaj   +1 more source

Table_1_Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma.docx

open access: yes, 2019
Hypoxia is a predominant feature in glioblastoma (GBM) and contributes greatly to its drug resistance. However, the molecular mechanisms which are responsible for the development of the resistant phenotype of GBM under hypoxic conditions remain unclear ...
Yixing Gao (6287018)   +11 more
core   +1 more source

ERK1/2-CEBPB Axis-Regulated hBD1 Enhances Anti-Tuberculosis Capacity in Alveolar Type II Epithelial Cells

open access: yes
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains a global health crisis with substantial morbidity and mortality rates. Type II alveolar epithelial cells (AEC-II) play a critical role in the pulmonary immune response against Mtb ...
Shiyun Yu   +13 more
core   +1 more source

Down-regulation of Cebpd mRNA requires Cebpb.

open access: yes, 2013
Phosphorimage quantitation of Northern blot analyses of whole ovary total RNA from 5 week-old Cebpb null mice (KO) or litter mate controls (WT) treated for 2 days with PMSG followed by hCG for the indicated times.
Mark Raffeld (82708)   +6 more
core   +1 more source

Bioinformatics and machine learning approaches to explore key biomarkers in muscle aging linked to adipogenesis

open access: yesBMC Musculoskeletal Disorders
Adipogenesis is intricately linked to the onset and progression of muscle aging; however, the relevant biomarkers remain unclear. This study sought to identify key genes associated with adipogenesis in the context of muscle aging.
Yumin Zhang, Li Qin, Juan Liu
doaj   +1 more source

Construction of molecular targets based on gene expression profiling and clinical validation results: CEBPB enables accurate diagnosis of early esophageal carcinoma

open access: yes
The prevalence of esophageal squamous cell carcinoma (ESCC) among all cases of esophageal carcinoma in Asia exceeds 90%. The absence of reliable biomarkers and noticeable symptoms in the early stages often leads to delayed diagnosis and unfavorable ...
Jin, shizhu
core   +1 more source

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