Results 31 to 40 of about 3,614 (168)

CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production

mLife, Volume 4, Issue 6, Page 651-663, December 2025.
Abstract Staphylococcus aureus is a notorious opportunistic pathogen with remarkable adaptability, enabling it to infect virtually every human tissue. Staphyloxanthin (STX), a critical virulence factor, contributes to S. aureus oxidative damage. However, the regulatory mechanism of STX production is incompletely understood.
Xian Chen, Huagang Peng, Xiancai Rao, Yi Yang, Keting Zhu, Zhen Hu, Shu Li, Xiaonan Huang, Feng Lin, Jianghong Wu, Weilong Shang, Renjie Zhou, Yifan Rao   +12 more
wiley   +1 more source

Metagenomic analysis of antibiotic-induced changes in gut microbiota in a pregnant rat model

Frontiers in Pharmacology, 2016
Food and Drug Administration (FDA, USA)-approved category B antibiotics are commonly prescribed to treat infections during pregnancy. The aim of this study was to investigate antibiotic-induced changes in gut microbiota (GM) that occur during pregnancy ...
Imran eKhan, Imran eKhan, Esam I Azhar, Esam I Azhar, Aymn eAbbas, Taha eKumosani, Elie eBarbour, Elie eBarbour, Didier eRaoult, Yasir eMuhammad   +9 more
doaj   +1 more source

Discrepancies in Beta‐Lactam Antibiotics Cross‐Reactivity: Implications for Clinical Practice

Allergy, Volume 80, Issue 11, Page 3108-3114, November 2025.
Four studies previously published on beta‐lactam antibiotics cross‐reactivity were compared head‐to‐head. These studies covered 51 antibiotics, theoretically leading to 2550 potential recommendations regarding alternatives in case of specific allergies. The studies analysed different sets of beta‐lactam antibiotics.
Evelien Maria Hutten, Maja Bulatović Ćalasan, Jason Anthony Trubiano, Rick Gert‐Jan Pleijhuis, Ingrid Terreehorst   +4 more
wiley   +1 more source

Clinical and Genetic Associations in Cephalosporin‐Induced Liver Injury: Insights From the Drug‐Induced Liver Injury Network

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 10, Page 1012-1022, November 2025.
Cephalosporin‐induced liver injury usually presents as a self‐limited, mixed, or cholestatic hepatitis without hypersensitivity features, typically developing 1 to 4 weeks after treatment. With cefazolin, it often occurs after a single parenteral dose. A strong genetic association has been found with HLA‐A*02:01, with more severe liver injury at onset.
Raj Vuppalanchi, Yi‐Ju Li, Don C. Rockey, Dina Halegoua‐DeMarzio, Robert J. Fontana, Herbert L. Bonkovsky, Christopher Koh, Joseph Odin, Huiman Barnhart, Jay H. Hoofnagle, Drug‐Induced Liver Injury Network (DILIN)   +10 more
wiley   +1 more source

Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria

Medicines, 2018
Background: The genera Abiotrophia and Granulicatella, previously known as nutritionally variant streptococci (NVS), are fastidious bacteria requiring vitamin B6 analogs for growth. They are members of human normal oral microbiota, and are supposed to be
Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima   +2 more
doaj   +1 more source

Prevalence of Post‐Operative Infections Related to Third Molar Surgery at an Australian University Teaching Clinic: A 5‐Year Retrospective Study

Oral Surgery, Volume 18, Issue 4, Page 451-461, November 2025.
ABSTRACT Aim To assess the prevalence of post‐operative infection related to surgical third molar extractions at a university teaching hospital. The secondary outcome was to investigate risk factors relating to post‐operative infections, including the use of prophylactic antibiotics.
Joshal Mehta, Riddhika Ram, Peter Reher
wiley   +1 more source

Matrine reverses the resistance of Haemophilus parasuis to cefaclor by inhibiting the mutations in penicillin-binding protein genes (ftsI and mrcA)

Frontiers in Microbiology
IntroductionMatrine (MT) is a potential resistance reversal agent. However, it remains unclear whether MT can reverse the resistance of Haemophilus parasuis (H.
JingChao Zhao, JingChao Zhao, Wen Yang, Wen Yang, Hui Deng, Hui Deng, Dong Li, QianYong Wang, LingXian Yi, LingXian Yi, QiHong Kuang, QiHong Kuang, Rui Xu, Rui Xu, Di Li, Di Li, RuoNan Li, RuoNan Li, DaoJin Yu, DaoJin Yu, Bo Yang, Bo Yang   +21 more
doaj   +1 more source

Simultaneous equation and area under the curve spectrophotometric methods for estimation of cefaclor in presence of its acid induced degradation product; A comparative study

Future Journal of Pharmaceutical Sciences, 2017
Two simple spectrophotometric methods were developed and validated for determination of cefaclor in presence of its acid induced degradation product; namely simultaneous equation method using two wavelengths 265 and 235 nm Method (A) and Area under the ...
Khalid A.M. Attia, Nasr M. Elabasawy, Ebrahim Abolmagd   +2 more
doaj   +1 more source

Phenotypic, Targeted Genotypic, and Antimicrobial Susceptibility Profiling of Extended‐Spectrum β‐Lactamase Production and Exclusive blaOXA−48 Gene Detection in Escherichia coli and Klebsiella pneumoniae Isolates From a South Lebanese Hospital

Journal of Clinical Laboratory Analysis, Volume 39, Issue 20, October 2025.
This study investigates the prevalence of multidrug‐resistant Escherichia coli and Klebsiella pneumoniae in South Lebanon's Saida region, focusing on ESBL and carbapenemase production. Results showed a high prevalence of ESBL producers (89.5%) and a lower rate of carbapenemase producers (10.5%), with blaCTX‐M being the most common ESBL gene.
Aya Kahil, Elie Salem Sokhn
wiley   +1 more source

Sobrevivência e perfil de resistência a antimicrobianos de Salmonella sp. isoladas em um sistema de tratamento de dejetos de suínos [PDF]

Ciência Rural, 2003
No presente estudo, foi avaliada a sobrevivência de Salmonella sp., presente em dejetos suínos, durante tratamento em um sistema de separação física e lagoas de estabilização ligadas em série. Nas amostras de Salmonella sp.
Verônica Schmidt, Marisa Ribeiro de Itapema Cardoso   +1 more
doaj   +1 more source