Results 51 to 60 of about 7,797 (210)

Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]

, 2017
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R, Guardabassi, L, Jana, B, Sigurðardóttir, H H   +3 more
core   +2 more sources

Discrepancies in Beta‐Lactam Antibiotics Cross‐Reactivity: Implications for Clinical Practice

Allergy, Volume 80, Issue 11, Page 3108-3114, November 2025.
Four studies previously published on beta‐lactam antibiotics cross‐reactivity were compared head‐to‐head. These studies covered 51 antibiotics, theoretically leading to 2550 potential recommendations regarding alternatives in case of specific allergies. The studies analysed different sets of beta‐lactam antibiotics.
Evelien Maria Hutten, Maja Bulatović Ćalasan, Jason Anthony Trubiano, Rick Gert‐Jan Pleijhuis, Ingrid Terreehorst   +4 more
wiley   +1 more source

Allergic Diseases in Common Variable Immunodeficiency: A Prospective Cross‐Sectional Study on Prevalence and Allergy Biomarkers of Clinical Phenotypes [PDF]

Scand J Immunol
Allergy occurred in 27% of 60 CVID patients, while IgE deficiency was observed in 65% and was strongly correlated with serum IgA levels. Low serum IgE/IgA levels accurately identified lymphoproliferative and granulomatous phenotypes, thereby improving diagnostic and prognostic stratification in CVID.
Danieli M, Claudi I, Auria S, Martini M, Buti E, Brunetto S, Moroncini G, Minciullo P, Gangemi S, Bilò M.   +9 more
europepmc   +2 more sources

Clinical and Genetic Associations in Cephalosporin‐Induced Liver Injury: Insights From the Drug‐Induced Liver Injury Network

Alimentary Pharmacology &Therapeutics, Volume 62, Issue 10, Page 1012-1022, November 2025.
Cephalosporin‐induced liver injury usually presents as a self‐limited, mixed, or cholestatic hepatitis without hypersensitivity features, typically developing 1 to 4 weeks after treatment. With cefazolin, it often occurs after a single parenteral dose. A strong genetic association has been found with HLA‐A*02:01, with more severe liver injury at onset.
Raj Vuppalanchi, Yi‐Ju Li, Don C. Rockey, Dina Halegoua‐DeMarzio, Robert J. Fontana, Herbert L. Bonkovsky, Christopher Koh, Joseph Odin, Huiman Barnhart, Jay H. Hoofnagle, Drug‐Induced Liver Injury Network (DILIN)   +10 more
wiley   +1 more source

Matrine reverses the resistance of Haemophilus parasuis to cefaclor by inhibiting the mutations in penicillin-binding protein genes (ftsI and mrcA)

Frontiers in Microbiology
IntroductionMatrine (MT) is a potential resistance reversal agent. However, it remains unclear whether MT can reverse the resistance of Haemophilus parasuis (H.
JingChao Zhao, JingChao Zhao, Wen Yang, Wen Yang, Hui Deng, Hui Deng, Dong Li, QianYong Wang, LingXian Yi, LingXian Yi, QiHong Kuang, QiHong Kuang, Rui Xu, Rui Xu, Di Li, Di Li, RuoNan Li, RuoNan Li, DaoJin Yu, DaoJin Yu, Bo Yang, Bo Yang   +21 more
doaj   +1 more source

Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria

Medicines, 2018
Background: The genera Abiotrophia and Granulicatella, previously known as nutritionally variant streptococci (NVS), are fastidious bacteria requiring vitamin B6 analogs for growth. They are members of human normal oral microbiota, and are supposed to be
Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima   +2 more
doaj   +1 more source

Treating acute sinusitis [PDF]

, 2000
Copyright © 2000 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holderInfections in the nose involve the sinuses because the lining of the ...
Wormald, P.
core   +2 more sources

Prevalence of Post‐Operative Infections Related to Third Molar Surgery at an Australian University Teaching Clinic: A 5‐Year Retrospective Study

Oral Surgery, Volume 18, Issue 4, Page 451-461, November 2025.
ABSTRACT Aim To assess the prevalence of post‐operative infection related to surgical third molar extractions at a university teaching hospital. The secondary outcome was to investigate risk factors relating to post‐operative infections, including the use of prophylactic antibiotics.
Joshal Mehta, Riddhika Ram, Peter Reher
wiley   +1 more source

Simultaneous equation and area under the curve spectrophotometric methods for estimation of cefaclor in presence of its acid induced degradation product; A comparative study

Future Journal of Pharmaceutical Sciences, 2017
Two simple spectrophotometric methods were developed and validated for determination of cefaclor in presence of its acid induced degradation product; namely simultaneous equation method using two wavelengths 265 and 235 nm Method (A) and Area under the ...
Khalid A.M. Attia, Nasr M. Elabasawy, Ebrahim Abolmagd   +2 more
doaj   +1 more source

Antibiotic Susceptibility Patterns and Penicillinase Activity of Staphylococci spp from Wound Specimens in Lagos [PDF]

, 2012
Forty-five Staphylococci spp comprising 33 (73.3%) Staphylococcus aureus and 12 (26.7%) Staphylococcus epidermidis isolated from both non-surgical and post-surgical septic wounds were evaluated for penicillinase activity.
Egwari, L. O., Opara, Morrison I.
core