Results 51 to 60 of about 4,854 (194)

Metagenomic analysis of antibiotic-induced changes in gut microbiota in a pregnant rat model

Frontiers in Pharmacology, 2016
Food and Drug Administration (FDA, USA)-approved category B antibiotics are commonly prescribed to treat infections during pregnancy. The aim of this study was to investigate antibiotic-induced changes in gut microbiota (GM) that occur during pregnancy ...
Imran eKhan, Imran eKhan, Esam I Azhar, Esam I Azhar, Aymn eAbbas, Taha eKumosani, Elie eBarbour, Elie eBarbour, Didier eRaoult, Yasir eMuhammad   +9 more
doaj   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 465-474, August 2026.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur, Jashvant D. Unadkat, Emily E. Fay, Nina Isoherranen, Mary F. Hebert   +4 more
wiley   +1 more source

Antibiotic sensitivity and RAPD-PCR studies on cultivable gut bacteria from Indian Medicinal Leech—Hirudinaria granulosa

Journal of Basic and Applied Zoology, 2020
Background Hirudo granulosa—an Indian cattle leech, is frequently used for the treatment of psoriasis and eczema. During treatment which followed by leech biting, it transfers some amount of gut microbes along with saliva.
Dhaval Patel, Khushbu Koriya, Pinkal Patel, Jyoti Solanki, Suresh Mesara, M. Nataraj   +5 more
doaj   +1 more source

Antimicrobial Resistance of Serratia marcescens Recovered From Aquatic Environments: A Review

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Serratia marcescens is a gram‐negative bacillus forming biofilms and showing multidrug resistance. Review (2019–2024) included 13 studies, 90 aquatic isolates. High resistance to β‐lactams, including carbapenems. Genes: blaOXA‐48, blaTEM‐1, aac(6′)‐Ic. Aquatic environments are reservoirs, requiring monitoring and control to prevent spread.
Heloisa Silva Inacio, Yasmim Raffaela Soares Santos, Magna Cristina de Paiva, Jaqueline Maria Siqueira Ferreira   +3 more
wiley   +1 more source

Matrine reverses the resistance of Haemophilus parasuis to cefaclor by inhibiting the mutations in penicillin-binding protein genes (ftsI and mrcA)

Frontiers in Microbiology
IntroductionMatrine (MT) is a potential resistance reversal agent. However, it remains unclear whether MT can reverse the resistance of Haemophilus parasuis (H.
JingChao Zhao, JingChao Zhao, Wen Yang, Wen Yang, Hui Deng, Hui Deng, Dong Li, QianYong Wang, LingXian Yi, LingXian Yi, QiHong Kuang, QiHong Kuang, Rui Xu, Rui Xu, Di Li, Di Li, RuoNan Li, RuoNan Li, DaoJin Yu, DaoJin Yu, Bo Yang, Bo Yang   +21 more
doaj   +1 more source

Case Report: Extrusion of a Sacral Nerve Implant Due to Engaging in Heavy Labor

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Sacral neuromodulation (SNM) is an effective treatment option for patients with an overactive bladder, non‐obstructive retention, and fecal incontinence. Although the risk of device extrusion is relatively low, if it occurs, it can lead to severe complications and undermine clinical outcomes.
Yu‐Sun Guo, Wen‐Tong Ji, Xiang‐Ze Wang, Run‐Hua Tang, Jian‐Long Wang   +4 more
wiley   +1 more source

이온성 고분자 매트릭스를 이용한 cefaclor 조절 방출

, 1998
Cefaclor의 치료효과의 증대 및 부작용의 경감을 위해서 이온성 고분자 매트릭스를 이용하여 조절방출 시스템을 설계하고자 하였다. Cefaclor가 양성 약물이므로 이온성 고분자와 약물간의 이온성 상호작용이 존재함을 예측할 수 있었으며, 이를 위장관 내에서 약물 방출을 제어함에 이용하였다.
백소임
core   +1 more source

Antimicrobial Susceptibilities of Oral Isolates of Abiotrophia and Granulicatella According to the Consensus Guidelines for Fastidious Bacteria

Medicines, 2018
Background: The genera Abiotrophia and Granulicatella, previously known as nutritionally variant streptococci (NVS), are fastidious bacteria requiring vitamin B6 analogs for growth. They are members of human normal oral microbiota, and are supposed to be
Taisei Kanamoto, Shigemi Terakubo, Hideki Nakashima   +2 more
doaj   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Simultaneous equation and area under the curve spectrophotometric methods for estimation of cefaclor in presence of its acid induced degradation product; A comparative study

Future Journal of Pharmaceutical Sciences, 2017
Two simple spectrophotometric methods were developed and validated for determination of cefaclor in presence of its acid induced degradation product; namely simultaneous equation method using two wavelengths 265 and 235 nm Method (A) and Area under the ...
Khalid A.M. Attia, Nasr M. Elabasawy, Ebrahim Abolmagd   +2 more
doaj   +1 more source