Results 51 to 60 of about 47,760 (259)

Metronidazole and cefazolin versus cefazolin alone for surgical site infection prophylaxis in gynecologic surgery at a comprehensive cancer center

American Journal of Obstetrics and Gynecology
Background: Surgical site infection (SSI) is one of the most common complications of gynecologic cancer surgery. Current guidelines recommend the administration of cefazolin pre-operatively to reduce SSI rates for patients undergoing clean-contaminated ...
A. Knisely, M. Iniesta, C. Marten, Gary B. Chisholm, K. Schmeler, Jolyn S. Taylor   +5 more
semanticscholar   +1 more source

Comparison of the Efficacy of Cefazolin with and without Naproxen in Patients with Cellulitis Admitted to a Tertiary Hospital: 2019-2020

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2022
Introduction: It is pertinent to carefully monitor the clinical course of patients with cellulitis. If not treated properly, there is a possibility of its extension to other skin surfaces, recurrent infection, risk of systemic spreading, and incidence of
Shabnam TEHRANI, Behnood HATAMI, Sadaf SAKET, Amirreza KEYVANFAR   +3 more
doaj   +1 more source

Antistaphylococcal Penicillin vs Cefazolin for the Treatment of Methicillin-Susceptible Staphylococcus aureus Spinal Epidural Abscesses

Open Forum Infectious Diseases, 2021
Cefazolin is commonly used as an alternative to antistaphylococcal penicillins (ASPs) in treating methicillin-susceptible Staphylococcus aureus (MSSA) infections; however, no study has compared these agents in MSSA spinal epidural abscess (SEA).
Cristina G. Corsini Campioli, J. R. Go, Omar M. Abu Saleh, D. Challener, Z. Yetmar, D. Osmon   +5 more
semanticscholar   +1 more source

Cefazolin-induced hemolytic anemia: a case report and systematic review of literature

European Journal of Medical Research, 2021
Background Cefazolin is a first-generation cephalosporin commonly used for skin and soft tissue infections, abdominal and orthopedic surgery prophylaxis, and methicillin-sensitive staph aureus.
Elizabeth Mause, Mohammad Selim, Manasa Velagapudi   +2 more
doaj   +1 more source

A comparison of the efficacy of single-dose cefazolin versus single-dose cefazolin plus 7-day mupirocin ointment wound application in preventing surgical site infection among patients undergoing major obstetric and gynecologic procedures at a tertiary university hospital: A single-blinded, randomized controlled trial

Philippine Journal of Obstetrics and Gynecology, 2021
BACKGROUND: Surgical site infection (SSI) is a common complication among all surgical cases. It is the most common nosocomial infection identified in the developing world with pooled incidence of 11.8 per 100 surgical procedures.
Mary Grace O. Cheng, Lylah D. Reyes, Jennifer T. Co   +2 more
doaj   +1 more source

Examining Cefazolin Utilization and Perioperative Anaphylaxis in Patients with and without a Penicillin Allergy Label: A Cross-Sectional Study

Journal of clinical anesthesia
Study Objective: To compare the occurrence of cefazolin perioperative anaphylaxis (POA) in patients with and without a penicillin allergy label (PAL) to determine whether the prevalence of cefazolin POA differs based on the presence of a PAL.
Zachary Murphy, Anum F. Muzaffar, Sandra A Massih, Eili Y. Klein, M. Dispenza, Valeria Fabre, Nadia B. Hensley, Kimberly G. Blumenthal, Santiago Alvarez-Arango   +8 more
semanticscholar   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Synergistic Antibacterial and Antibiotic Effects of Bisbenzylisoquinoline Alkaloids on Clinical Isolates of Methicillin-Resistant Staphylococcus Aureus (MRSA)

Molecules, 2011
The antibacterial activity of two bisbenzylisoquinoline alkaloids, tetrandrine (Tet) and demethyltetrandrine (d-Tet), alone and in combination with the antibiotics ampicillin (AMP), azithromycin (AZM), cefazolin (CFZ) and levofloxacin (LEV) against 10 ...
Wei-Dong Pan, Yun-Ling Zhang, Gen-Chun Wang, Tao Wang, Jun Han, Yang Li, Guo-Ying Zuo   +6 more
doaj   +1 more source