Results 101 to 110 of about 49,161 (205)

Prediction of Antibiotic Influence by Presence of Some β-lactamase Gene in AcinetobacterInfected Patients Hospitalized in Tehran, Iran [PDF]

open access: yes
Acinetobacter baumannii which is gram-negative rod and infecting hospitalized patient often develops multiple drug resistance patterns and causes serious problem in treatment.
آقابزرگی, سهراب   +8 more
core  

CEFEPIME/ENMETAZOBACTAM: Physicochemical Stability of a Novel β-Lactam/β-Lactamase Inhibitor Combination in Syringes and Elastomeric Devices

open access: yesAntibiotics
Background: Cefepime/enmetazobactam (FEP/META) is a novel fixed-dose β-lactam/β-lactamase inhibitor combination. The objective was to study the physicochemical stability of the approved daily dose in polypropylene syringes and elastomeric devices over a ...
Akim Chayem   +9 more
doaj   +1 more source

Cefepime monotherapy for the empirical treatment of fever in granulocytopenic cancer patients [PDF]

open access: yes, 2017
In a pilot study, we evaluated the efficacy and the safety of cefepime, a new cephalosporin with extended-spectrum activity against both Gram-positive and Gram-negative bacteria, as empirical monotherapy for 108 febrile episodes in 84 granulocytopenic ...
Aoun, M.   +4 more
core  

The effect of combined sewer overflows on the abundance of antibiotic resistance genes and bacteria in the James River [PDF]

open access: yes, 2017
Antibiotic resistance is a major threat to human health. Clinical situations are the main focus for antibiotic resistance research, but understanding the spread of resistance in the environment is also vital.
Levengood, Enjolie
core   +1 more source

Involvement of the blaCTX-M-3 gene in emergence of a peculiar resistance phenotype in Klebsiella pneumoniae

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionThis study aimed to investigate the mechanism underlying a peculiar resistance phenotype in Klebsiella pneumoniae, characterized by reduced susceptibility to cefepime compared to ceftazidime.MethodsAntimicrobial susceptibility testing ...
Peishan Li   +5 more
doaj   +1 more source

The Nephrotoxicity of Vancomycin. [PDF]

open access: yes, 2017
Farber, John L.   +2 more
core   +2 more sources

Development of resistance during ceftazidime and cefepime therapy in a murine peritonitis model [PDF]

open access: yes, 2017
Resistance emerging after ceftazidime or cefepime therapy was investigated in a peritonitis model. Mice were given a peritoneal challenge (102 cfu plus talcum) and treated by either antibiotic (50 mg/kg/dose, which produced similar antibiotic ...
Pechère, Jean-Claude   +1 more
core  

Cefepime versus carbapenem for treating complicated urinary tract infection caused by cefoxitin-nonsusceptible ESCPM organisms: a multicenter, real-world study

open access: yesBMC Infectious Diseases
Background This investigation aimed to compare the efficacy of cefepime and carbapenem for complicated urinary tract infection (cUTI) caused by presumptive AmpC β-lactamase-producing Enterobacter spp., Serratia marcescens, Citrobacter freundii ...
Liang Chen, Jie Hua, Xiaopu He
doaj   +1 more source

Risk of Potentially Neurotoxic Exposure in Infants Under High-Dose Cefepime Treatment—A Pharmacometric Simulation Study

open access: yesPharmaceutics
Background: Optimal dosing of cefepime in infants 1–2 months remains undefined. Objectives: We aimed to quantify the risk of potentially neurotoxic exposure with high-dose cefepime (50 mg/kg/8 h) in infants 1–2 months of age, as compared to adjacent age ...
Verena Gotta   +5 more
doaj   +1 more source

RISK FACTORS ASSOCIATED WITH URINARY TRACT INFECTION IN GERIATRIC AND ITS MICROBIOLOGIC CHARACTHERISTICS [PDF]

open access: yes, 2006
Background : Urinary Tract Infections(UTI) is a general understanding to describe invasion of microorganism in urinary tract. The severity of any functional disability, nature of underlying illnesses, anatomic or physiologic abnormalities of the ...
Dhanardhono, Tuntas
core  

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