Results 41 to 50 of about 49,161 (205)

National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]

, 2016
From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L, Jayol, A, Nordmann, P, Poirel, L   +3 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

In vitro Activity of a New Fourth-Generation Cephalosporin, Cefoselis, Against Clinically Important Bacterial Pathogens in China

Frontiers in Microbiology, 2020
The objective of this study was to systematically evaluate the in vitro activity of cefoselis and other comparators against common bacterial pathogens collected from 18 hospitals across China.
Jing-Wei Cheng, Jing-Wei Cheng, Jian-Rong Su, Meng Xiao, Meng Xiao, Shu-Ying Yu, Shu-Ying Yu, Shu-Ying Yu, Ge Zhang, Ge Zhang, Jing-Jia Zhang, Jing-Jia Zhang, Yang Yang, Yang Yang, Si-Meng Duan, Si-Meng Duan, Timothy Kudinha, Timothy Kudinha, Qi-Wen Yang, Qi-Wen Yang, Ying-Chun Xu, Ying-Chun Xu   +21 more
doaj   +1 more source

Antimicrobial susceptibility pattern and multidrug resistance ındex in Pseudomonas aeruginosa among clinical isolates in Denizli, Turkey [PDF]

, 2018
Background: Pseudomonas aeruginosa is an important hospital infection agent causing morbidity and mortality with the ability to gain resistance to many antimicrobials. The objective of this study was to determine the sensitivity profiles of nosocomial P.
Keskin, D., Kıraç, Selma, Yarar, M.
core   +2 more sources

Impact of COVID‐19 Pandemic on Antibiotic Resistance Patterns of Common Bacterial Pathogens to Antibiotics in Northern Ghana

Journal of Clinical Laboratory Analysis, EarlyView.
This retrospective study analyzed and compared antimicrobial resistance patterns of common bacterial pathogens before (October 2018–March 2020) and during (April 2020–December 2022) the COVID‐19 pandemic in Ghana's Northern Region. Amoxiclav (p = 0.027), ceftazidime (p = 0.002), ciprofloxacin (p = 0.001), gentamycin (p = 0.035), and meropenem (p < 0 ...
Hisham Alhassan Osumanu, Oliver Nangkuu Deberu, Abass Abdul‐Karim, Ahmed Alhassan, Ebenezer Kojo Addae, Stephen Opoku Afriyie, Stebleson Azure, Sadia Alimatu Lawal, Daron Davies Agboyie, Valentine Cheba Koyiri, Hudu Yakubu, Enoch Weikem Weyori, Kennedy Mensah Osei, Benjamin Demah Nuertey, Godfred Acheampong   +14 more
wiley   +1 more source

Comparative Analysis of the Effectiveness of Generic and Brand-Name Cefepime: A Multicenter Retrospective Cohort Study

Life
The clinical effectiveness of generic and brand-name cefepime in real-world settings remains unclear. Given the potential implications for healthcare costs and patient outcomes, this study aims to compare the efficacy and safety of these two formulations.
Chih-Huang Li, Peng-Hao Chang, Ching-Tai Huang, Chip-Jin Ng   +3 more
doaj   +1 more source

Presence of New Delhi metallo-β-lactamase gene (NDM-1) in a clinical isolate of Acinetobacter junii in Argentina [PDF]

, 2016
Here we report the presence of a clinically significant A. junii blaNDM-1 positive in a 38-year-old woman who was admitted to the emergency department with a fever and leg ulcers with signs of infection.
Almuzara, Marisa, Barberis, Claudia, Cittadini, Roxana, Del Castillo M,, Lazzaro, T., Montaña, Sabrina Daiana, Ramírez, M. S., Uong, S., Vay, Carlos Alberto   +8 more
core   +1 more source

Mortality after broad‐ versus narrow‐spectrum antibiotic treatment for patients with nursing and healthcare‐associated pneumonia: A nationwide retrospective cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi, Shotaro Aso, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga   +4 more
wiley   +1 more source

The Effect of Cefepime/Fluorothiazinone Compared with Cefepime/Placebo on Clinical Cure and Microbiological Eradication in Patients with Complicated Urinary Tract Infections: A Prospective Randomized Clinical Trial

Антибиотики и Химиотерапия
The multicenter prospective randomized trial of clinical and microbiological efficacy of cefepime in combination with fluorothiazinone or placebo was conducted to expand the possibilities of empirical therapy for patients with complicated urinary tract ...
V. B. Beloborodov, N. A. Zigangirova, N. L. Lubenec, A. B. Sheremet, S. A. Nelyubina, N. E. Bondareva, S. I. Luyksaar, E. Yu. Levchenko, S. V. Luyksaar, E. A. Koroleva, E. D. Fedina, D. Yu. Pushkar, A. L. Gintsburg   +12 more
doaj   +1 more source

Green Synthesis of ZnO Nanoparticles From Spirulina platensis: Antimicrobial and Cytotoxic Evaluation With Molecular Docking Studies

ChemistryOpen, EarlyView.
Algal‐extract‐derived ZnO nanoparticles show shape anisotropy and are bio capped by phytochemicals. These green‐synthesized NPs strongly inhibit S. aureus and K. pneumoniae biofilms. Molecular docking suggests stable binding of surface biomolecules to microbial targets, highlighting synergistic antibacterial mechanisms.
Muhammad Rizwan, Izaz Khan, Syed Sikandar Shah, Amir hamza khan, Abdurahman Hajinur Hirad, Saira Naz, Arshad Farid, Taimoor Khan, Said Hassan   +8 more
wiley   +1 more source