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Journal of Infection
AIMS This study aimed to evaluate the in vitro efficacy of cefiderocol and other agents against carbapenem-resistant Escherichia coli (CREC) clinical isolates in China and to elucidate the genetic mechanisms underlying cefiderocol resistance. METHODS A
Junxin Zhou, Qianyi Chen, Ying Cui
exaly +2 more sources
AIMS This study aimed to evaluate the in vitro efficacy of cefiderocol and other agents against carbapenem-resistant Escherichia coli (CREC) clinical isolates in China and to elucidate the genetic mechanisms underlying cefiderocol resistance. METHODS A
Junxin Zhou, Qianyi Chen, Ying Cui
exaly +2 more sources
CefiderocolFinder: a tool for detecting genetic adaptations implicated in cefiderocol resistance.
OBJECTIVES Cefiderocol is a novel last-resort cephalosporin antimicrobial increasingly used for difficult-to-treat infections by multidrug-resistant microorganisms (MDRO), and is effective against carbapenem-resistant Enterobacterales and Pseudomonas ...
Bryan van den Brand +57 more
semanticscholar +5 more sources
Rapid cefiderocol NP test for detection of cefiderocol susceptibility/resistance in Enterobacterales
Journal of Antimicrobial Chemotherapy, 2022Abstract Background Cefiderocol is among the latest generation of commercialized antibiotics against a large variety of MDR Gram-negative bacteria including carbapenem-resistant Enterobacterales and non-fermenters such as Pseudomonas aeruginosa and Acinetobacter baumannii.
Patrice Nordmann +3 more
openaire +2 more sources
Cefiderocol: Clinical application and emergence of resistance
Drug Resistance UpdatesAntibacterial drug resistance of gram-negative bacteria (GNB) results in high morbidity and mortality of GNB infection, seriously threaten human health globally. Developing new antibiotics has become the critical need for dealing with drug-resistant bacterial infections.
Hong Du
exaly +3 more sources
NDM-driven cefiderocol resistance: effect and therapeutic considerations.
The Lancet Infectious DiseasesBrenda A Warecki +3 more
semanticscholar +3 more sources

