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Emergence of antibiotic-resistant pneumococcal serotypes causing invasive pneumococcal disease in children, Spain. [PDF]
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Cefotaxime is a third-generation or extended-spectrum cephalosporin which was developed in the 1970s and approved by the US Food and Drug Administration (FDA) in 1981. Cefotaxime is (6R,7R)-3-(acetyloxymethyl)-7- [[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid; its formula is
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