Results 11 to 20 of about 51,719 (196)

Low Release Study of Cefotaxime by Functionalized Mesoporous Silica Nanomaterials

Gels, 2022
As a third-generation β-lactam antibiotic, cefotaxime shows a broad-spectrum with Gram-positive and Gram-negative bacteria activity and is included in WHO’s essential drug list.
Dan Eduard Mihaiescu, Daniela Istrati, Alina Moroșan, Maria Stanca, Bogdan Purcăreanu, Rodica Cristescu, Bogdan Ștefan Vasile, Roxana Doina Trușca   +7 more
doaj   +2 more sources

Rifaximin plus cefotaxime versus cefotaxime alone in treatment of spontaneous bacterial peritonitis in patients with cirrhosis

The Egyptian Journal of Internal Medicine, 2018
Background/purpose of the study Spontaneous bacterial peritonitis (SBP) is a cause of significantly higher morbidity and mortality in patients with cirrhosis. This study was conducted to assess the effect of adding rifaximin to cefotaxime in treatment of
Asmaa N Mohammad, Mahmoud K Elsamman, Amr M Zaghloul, Hameda H Mohamed, Walaa I Mohammed   +4 more
doaj   +2 more sources

Cefotaxime-Resistant Salmonella enterica in Travelers Returning from Thailand to Finland

Emerging Infectious Diseases, 2014
During 1993–2011, cefotaxime resistance among Salmonella enterica isolates from patients in Finland increased substantially. Most of these infections originated in Thailand; many were qnr positive and belonged to S.
Marianne Gunell, Laura Aulu, Jari Jalava, Susanna Lukinmaa-Åberg, Monica Österblad, Jukka Ollgren, Pentti Huovinen, Anja Siitonen, Antti J. Hakanen   +8 more
doaj   +1 more source

Uncovering the Important Genetic Factors for Growth during Cefotaxime-Gentamicin Combination Treatment in bla_CTX-M-1 Encoding Escherichia coli

Antibiotics, 2023
Due to the rapid spread of CTX-M type ESBLs, the rate of resistance to third-generation cephalosporin has increased among Gram-negative bacteria, especially in Escherichia coli, and there is a need to find ways to re-sensitize ESBL E.
Mosaed Saleh A. Alobaidallah, Vanesa García, Richard De Mets, Sandra M. Wellner, Line E. Thomsen, Ana Herrero-Fresno, John Elmerdahl Olsen   +6 more
doaj   +1 more source

Ventilator Associated Pneumonia in an Infant Caused by Stenotrophomonas maltophila – A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Stenotrophomonas maltophila (S.maltophila) is an aerobic Gram-negative bacillus that is a frequent colonizer of fluids used in the hospital setting. The organism is known to cause life threatening infections in immuno-compromised patients especially in ...
Neelima Angaali, Nina Dutta Roy, Sudharshan Raj Chitgupikar, Preeti Subramanian, Jaya Lakshmi Pabbati   +4 more
doaj   +1 more source

Identification of Genes Essential for Antibiotic-Induced Up-Regulation of Plasmid-Transfer-Genes in Cephalosporin Resistant Escherichia coli

Frontiers in Microbiology, 2019
Bacterial conjugation is one of the most important mechanisms for spread of antibiotic resistance among bacteria. We have previously demonstrated that cefotaxime (CTX) exposure up-regulates expression of Type-IV conjugation transfer genes, and that this ...
Gang Liu, John Elmerdahl Olsen, Line Elnif Thomsen   +2 more
doaj   +1 more source

Experimental Study of The Pharmacokinetics of Cefotaxime with Joint Administration of Drugs with Hyaluronidase Activity

Антибиотики и Химиотерапия, 2020
It Is shown that the preliminary administration of drugs that promote the flow of antibiotics into the lymphatic system increases the clinical effectiveness of treatment.
M. V. Zhuravleva, G. V. Kukushkin, L. P. Sviridkina, D. E. Yurov, T. R. Kameneva   +4 more
doaj   +1 more source

MALDI-TOF MS Approaches for the Identification of the Susceptibility of Extended-Spectrum β-Lactamases in Escherichia coli

Microorganisms, 2023
The increase in multidrug-resistant microorganisms that produce extended-spectrum β-lactamases (ESBLs) and carbapenemases is a serious problem worldwide. Recently, matrix-assisted laser desorption ionization–time-of-flight mass spectrometry (MALDI-TOF MS)
Yuriko Matsumura, Kazuko Ikegaya
doaj   +1 more source

Genomic Analysis of Third Generation Cephalosporin Resistant Escherichia coli from Dairy Cow Manure

Veterinary Sciences, 2017
The production of extended-spectrum β-lactamases (ESBLs) conferring resistance to new derivatives of β-lactams is a major public health threat if present in pathogenic Gram-negative bacteria. The objective of this study was to characterize ceftiofur (TIO)
Muhammad Attiq Rehman, Xianhua Yin, Dion Lepp, Chad Laing, Kim Ziebell, Guylaine Talbot, Edward Topp, Moussa Sory Diarra   +7 more
doaj   +1 more source

Evolutionary Responses to Acquiring a Multidrug Resistance Plasmid Are Dominated by Metabolic Functions across Diverse Escherichia coli Lineages

mSystems, 2023
Multidrug resistance (MDR) plasmids drive the spread of antibiotic resistance between bacterial lineages. The immediate impact of MDR plasmid acquisition on fitness and cellular processes varies among bacterial lineages, but how the evolutionary ...
Laura Carrilero, Steven J. Dunn, Robert A. Moran, Alan McNally, Michael A. Brockhurst   +4 more
doaj   +1 more source