Results 121 to 130 of about 45,696 (262)

In Vitro Efficacy of Ceftazidime-avibactam Against blaOXA-48 Carrying Klebsiella pneumoniae Isolates

, 2023
Introduction: The healthcare burden of carbapenem-resistant Klebsiella pneumoniae (K. pneumoniae) infections is growing. The newly developed beta-lactam/beta-lactamase inhibitor combination, ceftazidime-avibactam, shows promise in the treatment of such ...
Haluk Vahaboğlu, Demet HACISEYİTOĞLU, Rıza Aytaç Cetinkaya, Mücahide Esra Kocoglu, Yasemin Cag, Hülya Çaskurlu, Demet Hacıseyitoglu, Aylin Üsküdar Güclü, Hasan Cenk Mirza   +8 more
core   +1 more source

Ceftazidime-avibactam/aztreonam combination synergy against carbapenem-resistant Gram-negative isolates: In vitro study

Current Medicine Research and Practice
Background: The ceftazidime-avibactam combination is able to inhibit ESBLs, AmpCs and Class A carbapenemases and has been recommended for the treatment of complicated UTIs and ventilator-associated bacterial pneumonia.
Reena Rajan, A V Raghavendra Rao, Mathavi Suresh Kumar   +2 more
doaj   +1 more source

Ceftazidime-avibactam use for KPC-Kp infections: a retrospective observational multicenter study.

Clinical Infectious Diseases, 2021

semanticscholar   +1 more source

In vitro activity of ceftazidime-avibactam combination in in vitro checkerboard assays [PDF]

, 2015
Contains fulltext : 153132.pdf (Publisher’s version ) (Open Access)To evaluate the in vitro effects of the combination of ceftazidime and avibactam on the MICs of both compounds, checkerboard assays were performed for 81 clinical ...
Nichols, W.W., Melchers, M.J.B., Mouton, Johan, Melchers, MJ, van Mil, AC, Berkhout, J., Mil, A.C. van, Mouton †, J.W., Mouton, J.W., Berkhout, J, Nichols, WW   +10 more
core   +1 more source

Therapeutic drug monitoring of ceftazidime/avibactam: why one leg is not enough to run

Background: Therapeutic drug monitoring (TDM) is becoming an increasingly recommended approach for assessing optimal pharmacokinetic/pharmacodynamic (PK/PD) target attainment of ceftazidime/avibactam.
Gatti, Milo, Viale, Pierluigi, Pea, Federico   +2 more
core   +1 more source

Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline

, 2020
Ceftazidime/avibactam combines ceftazidime with a new beta-lactam that successfully that inhibits Amber Class A and D carbapenemases.We report a clinical case of a 61 year-old man with a carbapenemase-producing Klebsiella pneumoniae intra-abdominal ...
Mariana Guedes, Nuno Rocha-Pereira, Raquel Duro, Isabel Abreu, Telma Fonseca   +4 more
core   +1 more source

Multidrug-resistant Pseudomonas aeruginosa from sputum of patients with cystic fibrosis demonstrates a high rate of susceptibility to ceftazidime–avibactam

Infection and Drug Resistance, 2018
Stan D Atkin,1 Shadaan Abid,1 Michael Foster,1 Moumita Bose,1 Ashley Keller,1 Rita Hollaway,2 Helio S Sader,3 David E Greenberg,1,4 James D Finklea,1 Mariana Castanheira,3 Raksha Jain1,4 1Department of Internal Medicine, University of Texas Southwestern ...
Atkin SD, Abid S, Foster M, Bose M, Keller A, Hollaway R, Sader HS, Greenberg DE, Finklea JD, Castanheira M, Jain R   +10 more
doaj  

Prevalence and mortality of ceftazidime/avibactam-resistant KPC-producing Klebsiella pneumoniae bloodstream infections (2018–2022) [PDF]

Funding Information: Open access funding provided by Università degli Studi di Torino within the CRUI-CARE Agreement. This research was supported by EU funding within the MUR PNRR Extended Partnership initiative on Emerging Infectious Diseases (Project ...
Bianco, Gabriele, Costa, Cristina, Bastos, Paulo, Almeida, André, Cavallo, Rossana, Boattini, Matteo, Comini, Sara, De Rosa, Francesco Giuseppe, Corcione, Silvia   +8 more
core   +1 more source

Activity of ceftazidime-avibactam combinations against carbapenem-resistant Klebsiella pneumoniae assessed by checkerboard method

: The aim of this study is to detect the carbapenemase type and to determine the in vitro effects of ceftazidime/avibactam-colistin, ceftazidime/avibactam-meropenem and ceftazidime/avibactam-tigecycline combinations against Carbapenem-Resistant ...
Ayten Nur Uzun, Uzun, Ayten Nur, Hilal Tanriverdi, Tanriverdi, Hilal, GENÇ, SERPİL, Serpil Genç   +5 more
core   +1 more source

Comparative evaluation of early treatment with ceftolozane/tazobactam versus ceftazidime/avibactam for non-COVID-19 patients with pneumonia due to multidrug-resistant Pseudomonas aeruginosa

Journal of Antimicrobial Chemotherapy
Background Ceftolozane/tazobactam and ceftazidime/avibactam are commonly used in patients with MDR-Pseudomonas aeruginosa (PSA) pneumonia (PNA). This study compared outcomes between non-COVID-19 hospitalized patients with MDR-PSA PNA who received ...
T. Lodise, E. Obi, Alexandre H. Watanabe, Emre Yucel, Jae S. Min, Brian H Nathanson   +5 more
semanticscholar   +1 more source