Results 101 to 110 of about 63,048 (236)
Chitosan Nanoparticles as a Mucoadhesive Drug Delivery System for Ocular Administration
Marine Drugs, 2017 Pharmaceutical approaches based on nanotechnologies and the development of eye drops composed of the mucoadhesive polymers chitosan and hyaluronic acid are emerging strategies for the efficient treatment of ocular diseases.
Mariana M. Silva +5 more
doaj +1 more source
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
Veterinary Dermatology, Volume 37, Issue 5, Page 581-591, October 2026.ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 18, 28 September 2026.This review explores the potential of multimetallic organic framework (MMOF) composites as photocatalysts. It demonstrates the impact of the composite architecture on the photocatalytic performance and existing challenges. The paper highlights heterojunction mechanisms and the role of each partner composites in degradation, CO2 reduction, H2 production,
Youjian Chen +8 more
wiley +1 more source
Advanced Science, Volume 13, Issue 50, 7 September 2026.Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang +19 more
wiley +1 more source
Carbapenem-resistant Enterobacterales (CRE) due to Metallo-β-lactamase (MBL) production are treated with either polymyxins or the novel combination of ceftazidime-avibactam and aztreonam (AA).
Abi Manesh (9552389) +4 more
core +1 more source
Ceftazidime-Avibactam: a Novel Cephalosporin/β-lactamase Inhibitor Combination
, 2013 Avibactam (formerly NXL104, AVE1330A) is a synthetic non-β-lactam, β-lactamase inhibitor that inhibits the activities of Ambler class A and C β-lactamases and some Ambler class D enzymes. This review summarizes the existing data published for ceftazidime-
Hoban, Daryl J. +11 more
core +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3161-3168, September 2026.Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis +5 more
wiley +1 more source
, 2010 Objective: To evaluate cefditoren in inducer-substrate combinations to screen for AmpC induction. Methods: 100 clinical isolates (25 P. aeruginosa, 25 E. cloacae, 14 M. morganii, 13 S. marcescens, 12 C. freundii, 7 P. rettgeri, and 4 E.
Coronel, Pilar +8 more
core +1 more source
Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3017-3026, September 2026.Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo +9 more
wiley +1 more source