Results 61 to 70 of about 47,590 (163)

Effect of surgical antimicrobial prophylaxis duration for colic surgery on complications and resistome

Equine Veterinary Journal, Volume 58, Issue 2, Page 390-403, March 2026.
Abstract Background Based on human studies, surgical antimicrobial (AMD) prophylaxis (SAP) beyond 24 h is unnecessary and potentially detrimental. Objective To compare clinical and microbiological outcomes in patients receiving 24‐ or 72‐h of SAP for colic surgery. Study Design Prospective randomised clinical trial.
Louise L. Southwood, Alicia Long, Jairo Perez, Scott Daniel, Kyle Bittinger, Maia Aitken, Laurel Redding   +6 more
wiley   +1 more source

Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering

mBio, 2017
The emergence of Klebsiella pneumoniae carbapenemases (KPCs), β-lactamases that inactivate “last-line” antibiotics such as imipenem, represents a major challenge to contemporary antibiotic therapies.
Melissa D. Barnes, Marisa L. Winkler, Magdalena A. Taracila, Malcolm G. Page, Eric Desarbre, Barry N. Kreiswirth, Ryan K. Shields, Minh-Hong Nguyen, Cornelius Clancy, Brad Spellberg, Krisztina M. Papp-Wallace, Robert A. Bonomo   +11 more
doaj   +1 more source

Feasibility of Recycled Polypropylene for Reusable Food Packaging: Effects of Reuse Conditions on Packaging Performance, Material Properties, and Microbial Safety

Food Frontiers, Volume 7, Issue 2, March 2026.
This study demonstrates that postindustrial recycled polypropylene (PIR PP) performs comparably to virgin polypropylene in reusable food packaging. After 20 simulated reuse cycles, including heating and commercial washing, PIR PP retained its structural, chemical, and microbial safety properties, supporting its potential for safe and sustainable ...
Caolan Jameson, Ronan Farrell, Susan McKenna, Romina Pezzoli, Vlasta Chyzna, Daniel P. Fitzpatrick, Michael Hopkins, Yvonne J. Cortese   +7 more
wiley   +1 more source

Bacterial Profiling and Antibiotic Resistance Pattern of Uropathogens Isolated From Adolescent Girls With Bacteriuria: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls. Methods This is a cross‐sectional
Shimaa Abdelrahim Khalaf, Mona Gamal Mohamed, Amal A. Elkhawaga, Iftekhar Ahmed, Md. Rabiul Islam, Shaimaa M. Goda   +5 more
wiley   +1 more source

Cellulose‐Based Nanocomposites in Drug Delivery and Antimicrobial Therapies: Emerging Innovations and Translational Outlook

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Applications of cellulose‐based nanocomposites in antimicrobial drug delivery. ABSTRACT Cellulose‐based nanocomposites have emerged as sustainable and versatile biomaterials with promising applications in drug delivery and antimicrobial therapy.
Suraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Javedh Shareef   +4 more
wiley   +1 more source

Bacteriophage Therapy: Current Strategies and Future Perspectives

MedComm, Volume 7, Issue 3, March 2026.
This manuscript systematically reviews the expanding scope of phage applications. It moves beyond traditional antibacterial use to explore their role in precision therapies against drug‐resistant infections, their synergy with antibiotics, and advanced biomaterial‐assisted delivery systems.
Zihe Zhou, Hanyu Fu, Mengzhe Li, Zhongyu Han, Zhenchao Wu, Huahao Fan, Ning Shen, Jiajia Zheng   +7 more
wiley   +1 more source

A Case of Effective Long‐Term Tobramycin Inhalation in a Patient With Bronchiectasis and Refractory Pseudomonas aeruginosa Infection

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of bronchiectasis with persistent P. aeruginosa infection successfully managed with inhaled tobramycin after long‐term macrolide therapy failed to prevent recurrent exacerbations. ABSTRACT Bronchiectasis predisposes patients to refractory airway infections and significantly reduces their quality of life.
Yasuaki Kotetsu, Nobuyuki Kawaguchi, Maako Nakajima, Ayaka Shiota, Yasuyoshi Washio, Akiko Ishimatsu, Junji Otsuka, Kazuhito Taguchi, Atsushi Moriwaki, Makoto Yoshida   +9 more
wiley   +1 more source

Invasomes and Nanostructured Lipid Carriers for Targeted Delivery of Ceftazidime Combined with N-Acetylcysteine: A Novel Approach to Treat Pseudomonas aeruginosa-Induced Keratitis

Pharmaceutics
Objectives: This study was designed to optimize a ceftazidime (CTZ)-loaded nanocarrier that could efficiently permeate across corneal tissues. Moreover, N-acetylcysteine (NAC) was combined with an optimized CTZ-loaded formula to augment the antimicrobial
Mina Josef, Menna M. Abdellatif, Rehab Abdelmonem, Mohamed A. El-Nabarawi, Mahmoud Teaima, Hadeer M. Bedair, Alshaimaa Attia   +6 more
doaj   +1 more source

Prevalence of Meningitis Among Neonates With Sepsis: Analysis of Predictors at a Tertiary Care Hospital in Bangladesh

Reproductive, Female and Child Health, Volume 5, Issue 1, March 2026.
ABSTRACT Objective To identify the prevalence of neonatal meningitis and to describe the clinical, haematological and bacteriological profiles of neonatal sepsis and meningitis. This study also aimed to identify the factors predictive of meningitis among neonates with sepsis.
Syeda Humaida Hasan, Humayra Akter, Jagadish C. Das, Adrita Das   +3 more
wiley   +1 more source

An antisense peptide-conjugated peptide nucleic acid (PPNA) for peptidoglycan recycling inhibition reduces AmpC hyperproduction and β–lactam resistance in Pseudomonas aeruginosa

Microbiology Spectrum
We performed a proof-of-concept study to validate a peptide-conjugated peptide nucleic acid (PPNA) directed to inhibit peptidoglycan recycling as strategy to reduce AmpC hyperproduction and β-lactam resistance in Pseudomonas aeruginosa.
Maria Escobar-Salom, Isabel M. Barceló, Jordi Sansó-Sastre, Gabriel Torrens, Elena Jordana-Lluch, Bartolomé Moyà, Antonio Oliver, Carlos Juan   +7 more
doaj   +1 more source