Results 41 to 50 of about 58,249 (234)
Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis
British Journal of Clinical Pharmacology, EarlyView.Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood +6 more
wiley +1 more source
, 2018 Purpose: To evaluate whether Siamese crocodile plasma exhibits antibacterial properties and if it synergizes with ceftazidime against ceftazidime-resistant Enterobacter cloacae (CREnC).Methods: Protein fractions were from crocodile plasma and tested them
Temsiripong, Yosapong +3 more
core +1 more source
Efficacy of ceftazidime-avibactam in a rat intra-abdominal abscess model against a ceftazidime- and meropenem-resistant isolate of Klebsiella pneumoniae carrying blaKPC-2 [PDF]
, 2017 Efficacies of ceftazidime-avibactam (4:1 w/w) and ceftazidime were tested against ceftazidime-susceptible (blaKPC-2-negative), and meropenem- and ceftazidime-resistant (blaKPC-2-positive), Klebsiella pneumoniae in a 52-h, multiple dose, abdominal abscess
Pop-Damkov, P. +13 more
core +1 more source
Ceftazidime and meropenem MIC for engineered mutants.
, 2023 Ceftazidime and meropenem MIC for engineered mutants.
Kay A. Ramsay (11856887) +7 more
core +1 more source
In-vitro activity of oxymino-cephalosporins with and without sulbactam against Class A Extended-spectrum β-lactamase producing E.coli [PDF]
Journal of Microbiology and Infectious Diseases, 2011 Objectives: The primary aim of this study was to determine the activities of ceftazidime and cefepime combined tosulbactam against class A extended-spectrum β lactamases (ESBLs).Materials and methods: Eight university hospitals participated to the study ...
Haluk Vahaboğlu +2 more
doaj
Chitosan Nanoparticles as a Mucoadhesive Drug Delivery System for Ocular Administration
Marine Drugs, 2017 Pharmaceutical approaches based on nanotechnologies and the development of eye drops composed of the mucoadhesive polymers chitosan and hyaluronic acid are emerging strategies for the efficient treatment of ocular diseases.
Mariana M. Silva +5 more
doaj +1 more source
Food Safety and Health, EarlyView.This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi +6 more
wiley +1 more source
, 2023 Jiaxin Yu,1,2 Wei Zuo,1,2 Hongwei Fan,1,3 Jiayu Wu,1,2 Luyao Qiao,1,2,4 Benyu Yang,1,2,5 Wenxi Li,1,2,5 Yang Yang,1,2,* Bo Zhang1,2,* 1Department of Pharmacy, Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2State Key ...
Zuo W +8 more
core
In Vitro Evaluation of Increasing Avibactam Concentrations on Ceftazidime Activity against Ceftazidime/Avibactam-Susceptible and Resistant KPC-Producing Klebsiella pneumoniae Clinical Isolates [PDF]
, 2023 The novel beta-lactam/beta-lactamase inhibitor combinations (beta L-beta LICs) are one of the last-line resources available against multidrug-resistant (MDR) Gram-negative bacteria.
Secci, Benedetta +11 more
core +1 more source
Applied Microbiology, 2023 Pseudomonas aeruginosa, a Gram-negative, rod-shaped bacterium, holds a prominent position as an antibiotic-resistant priority pathogen, according to the World Health Organization.
Evan Kello +6 more
doaj +1 more source