Discrepancies in Beta‐Lactam Antibiotics Cross‐Reactivity: Implications for Clinical Practice
Four studies previously published on beta‐lactam antibiotics cross‐reactivity were compared head‐to‐head. These studies covered 51 antibiotics, theoretically leading to 2550 potential recommendations regarding alternatives in case of specific allergies. The studies analysed different sets of beta‐lactam antibiotics.
Evelien Maria Hutten +4 more
wiley +1 more source
2165. Assessing the Impact of Meropenem Exposure on Ceftolozane/tazobactam-resistance Development in Pseudomonas aeruginosa using in vitro Serial Passage [PDF]
Aliaa Fouad +5 more
openalex +1 more source
Advances in antibiotic therapy in the critically ill [PDF]
Infections occur frequently in critically ill patients and their management can be challenging for various reasons, including delayed diagnosis, difficulties identifying causative microorganisms, and the high prevalence of antibiotic-resistant strains ...
Antonelli, Massimo +13 more
core +2 more sources
Summary Understanding bloodstream infection (BSI) epidemiology is crucial for optimizing antibiotic therapy in paediatric haematology–oncology patients undergoing chemotherapy or haematopoietic cell transplantation (HCT). However, updated paediatric data remain scarce.
Francesco Baccelli +35 more
wiley +1 more source
Combined Resistance to Ceftolozane-Tazobactam and Ceftazidime-Avibactam in Extensively Drug-Resistant (XDR) and Multidrug-Resistant (MDR) Pseudomonas aeruginosa: Resistance Predictors and Impact on Clinical Outcomes Besides Implications for Antimicrobial Stewardship Programs [PDF]
Marianna Meschiari +6 more
openalex +1 more source
Increasing proportion of carbapenemase-producing Enterobacteriaceae and emergence of a MCR-1 producer through a multicentric study among hospital-based and private laboratories in Belgium from September to November 2015 [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) strains have been increasingly reported in Belgium. We aimed to determine the proportion of CPE among Enterobacteriaceae isolated from hospitalised patients and community outpatients in Belgium in 2015 ...
Bauraing, Caroline +8 more
core +1 more source
A review of antibiotic safety in pregnancy—2025 update
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen +8 more
wiley +1 more source
identifying allosteric networks to fight antibiotics resistance [PDF]
The rise of multi-drug resistance in bacterial pathogens is one of the grand challenges facing medical science. A major concern is the speed of development of β-lactamase-mediated resistance in Gram-negative species, thus putting at risk the efficacy of ...
Afsharikho, Hamidreza +9 more
core +1 more source
Herein, we report the case of an 82‐year‐old male with pleural mesothelioma who developed steroid‐refractory immune‐related pneumonitis after treatment with ipilimumab and nivolumab, which was successfully managed by mycophenolate mofetil treatment. ABSTRACT Steroid‐refractory immune‐related pneumonitis is a clinical challenge with limited evidence ...
Hiroaki Ota +12 more
wiley +1 more source

