Results 1 to 10 of about 76,145 (237)

Piperacillin–tazobactam tolerability in patients with a labeled penicillin allergy (PIPPEN) [PDF]

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Background: Piperacillin–tazobactam is a beta-lactam antibiotic with a distinct R1 side chain compared to other penicillins, therefore the risk of cross-reactivity should be theoretically low.
Avneet Purewal   +4 more
doaj   +2 more sources

Piperacillin–tazobactam-associated thrombocytopenia with negative antiplatelet antibody testing: a case report and literature review [PDF]

open access: yesFrontiers in Medicine
BackgroundPiperacillin–tazobactam is a widely used antibiotic. Although rare, thrombocytopenia related to piperacillin–tazobactam can be clinically significant. Drug-induced immune thrombocytopenia (DIIT) is difficult to distinguish from thrombocytopenia
Pengcheng Tian   +8 more
doaj   +2 more sources

Deciphering the emergence of mutations in Pseudomonas aeruginosa after ceftolozane/tazobactam treatment and evaluating therapeutic alternatives [PDF]

open access: yesBMC Microbiology
Objectives Ceftolozane/tazobactam is a relevant option for treating multiresistant Pseudomonas aeruginosa, a major public health problem. Over a 14-month period, we studied the frequency of ceftolozane/tazobactam resistance development and mechanisms ...
Léa Bientz   +13 more
doaj   +2 more sources

Antimicrobial activity of high-dose cefepime-tazobactam (WCK 4282) against a large collection of gram-negative organisms collected worldwide in 2018 and 2019

open access: yesInternational Journal of Infectious Diseases, 2022
: Background: High-dose cefepime-tazobactam (WCK 4282) is currently under clinical development at a dosage of 2 grams/2 grams every 8 hours with prolonged infusion (90 minutes).
Helio S. Sader   +3 more
doaj   +1 more source

Case Report: Drug-Induced Immune Haemolytic Anaemia Caused by Cefoperazone-Tazobactam/ Sulbactam Combination Therapy

open access: yesFrontiers in Medicine, 2021
There has previously been a report of a patient developing haemolytic anaemia following exposure to cefoperazone. Another case has been reported involving the detection of cefoperazone-dependent antibodies in the absence of immune haemolytic anaemia.
Yuanjun Wu   +7 more
doaj   +1 more source

Comparison of Piperacillin and Tazobactam Pharmacokinetics in Critically Ill Patients with Trauma or with Burn

open access: yesAntibiotics, 2022
Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics.
Daniel J. Selig   +7 more
doaj   +1 more source

Simple HPLC-UV Method for Piperacillin/Tazobactam Assay in Human Plasma

open access: yesAntibiotics, 2023
Background: Piperacillin (Pip)/tazobactam (Taz) is a broad-spectrum antimicrobial agent that has been commonly used in the intensive care unit for severe and life-threatening infections. Recent evidence suggests that therapeutic drug monitoring (TDM) for
Khaled Abdelkawy   +2 more
doaj   +1 more source

Ceftolozane/Tazobactam [PDF]

open access: yesHospital Pharmacy, 2015
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing
Dennis J, Cada   +3 more
openaire   +2 more sources

Design of an Experimental Study for the Simultaneous Determination of Cefepime, Piperacillin and Tazobactam Using Micellar Organic Solvent-Free HPLC

open access: yesSeparations, 2022
Application of Sustainable analytical chemistry concepts has become crucial in order to remove the environmentally harmful impacts originating from the routine use of analytical techniques.
Hani M. Hafez   +6 more
doaj   +1 more source

Cost-effectiveness of ceftolozane/tazobactam for the treatment of complicated intraabdominal and urinary tract infections in Colombia

open access: yesInfectio, 2020
Objective: To evaluate the cost-effectiveness of ceftolozane/tazobactam + metronidazole (C/T+M) and ceftolozane/tazobactam (C/T) compared with 8 alternatives used in the treatment of complicated intraabdominal infection (cIAI) and complicated urinary ...
Fabián Hernández
doaj   +1 more source

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