Results 31 to 40 of about 76,145 (237)

Evaluation of synergistic effect of tazobactam with meropenem and ciprofloxacin against multi-drug resistant Acinetobacter baumannii isolated from burn patients in Tehran

GMS Hygiene and Infection Control, 2019
Background: is an increasingly important cause of nosocomial infections worldwide. In addition to the intrinsic resistance of to many antibiotics, available treatment approaches with older antibiotics are significantly associated with an increase in ...
Valadan Tahbaz, Sahel, Azimi, Leila, Asadian, Mahla, Lari, Abdolaziz Rastegar   +3 more
doaj   +1 more source

Activity of ceftolozane/tazobactam against commonly encountered antimicrobial resistant Gram-negative bacteria in Lebanon

Journal of Infection in Developing Countries, 2020
Introduction: In view of the continuous rise in Gram-negative bacterial resistance and limited treatment options, Ceftolozane/tazobactam (C/T) is a newly introduced antimicrobial agent in Lebanon for its demonstrated activity against resistant Gram ...
George F Araj, Dana M Berjawi, Umayya Musharrafieh, Nancy K El Beayni   +3 more
doaj   +1 more source

Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis [PDF]

, 2018
In a retrospective analysis of 215 patients with carbapenem-resistant Pseudomonas aeruginosa sepsis, we observed a significantly higher risk of mortality associated with respiratory tract infection (risk ratio [RR], 1.20; 95 ...
Britt, Nicholas S, Burnham, Carey-Ann D, Durkin, Michael J, Hampton, Nicholas B, Kollef, Marin H, Micek, Scott T, Ritchie, David J   +6 more
core   +2 more sources

Piperacillin/Tazobactam-Induced Neutropenia: A Case Report [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2012
Neutropenia, secondary to immune destruction or maturation arrest, is commonly described as an adverse hematological effect of beta-lactam antibiotics. A 29-year-old woman was being treated with piperacillin/tazobactam due to draining heel osteomyelitis.
Hayati DEMİRASLAN, Sibel GÜRBÜZ, Zehra DOĞAN TOMUL, İlhami ÇELİK   +3 more
doaj  

Evaluation of in vitro activity of ceftolozane–tazobactam against recent clinical bacterial isolates from Brazil – the EM200 study

Brazilian Journal of Infectious Diseases, 2020
Background: The emergence of antibiotic resistance is increasing and there are few effective antibiotics to treat infections caused by resistant and multidrug resistant bacterial pathogens.
Felipe Francisco Tuon, Juliette Cieslinski, Suellen da Silva Rodrigues, Fernando Brandão Serra, Marina Della-Negra de Paula   +4 more
doaj   +1 more source

MUTAGENICITY TESTS OF TAZOBACTAM/PIPERACILLIN, TAZOBACTAM AND PIPERACILLIN

The Journal of Toxicological Sciences, 1994
As a part of safety tests of tazobactam/piperacillin (TAZ/PIPC), the reverse mutation tests using bacteria, the chromosomal aberration tests using cultured cells and the micronucleus tests using male mice were conducted in order to evaluate the in vitro and in vivo mutagenicity of TAZ, PIPC, TAZ/PIPC. 1.
A, Ohuchida, A, Taniguti, Y, Kouchi, Y, Maeda, A, Kashihara, S, Omae   +5 more
openaire   +3 more sources

ANTIGENICITY TESTS OF TAZOBACTAM/PIPERACILLIN, TAZOBACTAM AND PIPERACILLIN

The Journal of Toxicological Sciences, 1994
The antigenicity tests of Tazobactam/piperacillin (TAZ/PIPC), tazobactam (TAZ:beta-lactamase inhibitor) and piperacillin (PIPC:penicillin antibiotic) were performed in mice and guinea pigs. The following results were obtained. 1. TAZ/PIPC, TAZ or PIPC had no immunogenicity and allergenicity in either passive cutaneous anaphylaxis (PCA) test using BALB ...
M, Takemoto, K, Matsuo, M, Oguro, Y, Kouchi   +3 more
openaire   +3 more sources

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

SINGLE-DOSE TOXICITY STUDIES OF TAZOBACTAM/PIPERACILLIN AND TAZOBACTAM

The Journal of Toxicological Sciences, 1994
Tazobactam (TAZ) is a newly developed beta-lactamase inhibitor. Tazobactam/Piperacillin (TAZ/PIPC) is a formulation consisting of TAZ and PIPC in a ratio of 1:4. Singe-dose toxicity studies in TAZ/PIPC and TAZ were carried out using mice and rats of both sexes and male dogs. The results were as follows. 1.
T, Hayashi, H, Yada, M, Anai, T, Umano, K, Kawazu, S, Anai, T, Kaziwara, K, Yamasaki   +7 more
openaire   +3 more sources

European intensive care physicians’ experience of infections due to antibiotic-resistant bacteria [PDF]

, 2020
Background Antimicrobial resistance (AMR) compromises the treatment of patients with serious infections in intensive care units (ICUs), and intensive care physicians are increasingly facing patients with bacterial infections with limited or no adequate ...
De Waele, Jan, Friggeri, Arnaud, Garnacho-Montero, José, Gustin, Marie Paule, Jean, Astrid, Kohlenberg, Anke, Lepape, Alain, Monnet, Dominique L., Savey, Anne, Vanhems, Philippe   +9 more
core   +2 more sources