Results 81 to 90 of about 7,581 (239)

Healthcare Resource Utilization of Ceftolozane/Tazobactam Versus Meropenem for Ventilated Nosocomial Pneumonia from the Randomized, Controlled, Double-Blind ASPECT-NP Trial

Infectious Diseases and Therapy, 2020
Introduction Hospital-acquired and ventilator-associated bacterial pneumonia (HABP and VABP) are associated with significant healthcare resource utilization (HCRU).
Thomas Lodise, Joe Yang, Laura A. Puzniak, Ryan Dillon, Marin Kollef   +4 more
doaj   +1 more source

Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage [PDF]

, 2016
We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam
Casabar, Ed, Durkin, Michael J, Hays, Amanda J, Hsueh, Kevin, Jafarzadeh, S. Reza, Krekel, Tamara, Lane, Michael A, Reyes, Maria, Ritchie, David J   +8 more
core   +2 more sources

Abstract Supplement

Pulmonary Medicine, Volume 2026, Issue 1, 2026.
 
Marzia Folegani, Semonti Nandi
wiley   +1 more source

Evaluation of in Vitro Activity of Ceftazidime/Avibactam and Ceftolozane/Tazobactam against ESBL-producing Enterobacterales Isolated from Intensive Care Units from Qatar

Oman Medical Journal, 2022
Objectives: Extended-spectrum β-lactamases (ESBLs) mechanism of resistance in Enterobacterales leads to poor clinical outcomes. Ceftazidime/avibactam and ceftolozane/tazobactam are two broad-spectrum antimicrobial combinations that are effective against ...
Mazen A. Sid Ahmed, Emad Bashir Ibrahim, Jemal M. Hamid, Joanne Daghfal, Mohammed A. Alyazidi, Aimen H. Abdelwahab, Muna A. Al-Maslamani, Abdul Latif Al Khal, Hamad Abdel Hadi   +8 more
doaj   +1 more source

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone [PDF]

, 2017
Emergence of epidemic clones and antibiotic resistance development compromises the management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections.
Cabot, Gabriel, Cantón, Rafael, Figuerola, Joan, Johansen, Helle Krogh, Kidd, Timothy J., López-Causapé, Carla, Madsen Sommer, Lea Mette, Molin, Søren, Ocampo-Sosa, Alain A., Oliver, Antonio, Rubio, Rosa   +10 more
core   +1 more source

Rectal Carriage of Sequence Type 307 Klebsiella pneumoniae High‐Risk Clone Harboring Multiple Carbapenemase Genes in Community Hospitals Gauteng, South Africa

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Graphical presentation of rectal carriage of carbapenem‐resistant Klebsiella pneumoniae, highlighting ST307 high‐risk clone and IncX3 plasmid‐associated blaOXA‐181. This study highlights the threat linked to horizontal gene transfer of AMR genes by epidemic plasmids from Klebsiella pneumoniae high‐risk clones to other bacterial species.
Kafilat Taiwo Salvador‐Oke, Johann Pitout, Gisele Peirano, Kathy‐Anne Strydom, Chanel Kingsburgh, Marthie Ehlers, Marleen Kock   +6 more
wiley   +1 more source

Global evaluation of the antibacterial activity of Ceftolozane/Tazobactam against ESBLs-producing and : a systematic review and meta-analysis

Therapeutic Advances in Infectious Disease, 2023
Background: Ceftolozane/Tazobactam is a β-lactam/β-lactamase inhibitor combination with a high range of efficacy and broad-spectrum action against multidrug-resistant bacterial strains. Objectives: The present study aimed to analyze the in vitro activity
Marzieh Rahim Khorasani, Soodabeh Rostami, Arash Bakhshi, Raheleh Sheikhi   +3 more
doaj   +1 more source

Ceftolozane/tazobactam: Novelantipseudomonal cephalosporin [PDF]

Pharmacy Today, 2015
Abstract Another much-needed antibiotic enters the marketplace with FDA'sapproval of ceftolozane/tazobactam (Zerbaxa—Cubist) for the treatmentof adult patients with complicated intra-abdominal infections(cIAI) in combination with metronidazole and for complicated urinarytract infections (cUTI), including pyelonephritis.
openaire   +1 more source

Management of intra-abdominal infections : recommendations by the WSES 2016 consensus conference [PDF]

, 2017
This paper reports on the consensus conference on the management of intra-abdominal infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual World Society of Emergency Surgery (WSES) meeting. This document covers all
A Betsch, A Billing, A Billing, A Bufalari, A Castellanos-Ortega, A Clegg, A Esteban, A Neri, A Prkno, A Rodríguez, A Sanabria, A Sitges-Serra, A Sotto, A Tabah, A Witczak, AB Almeida, Addison K. May, Andrew Peitzman, Andrew W. Kirkpatrick, AR Novotny, Ari Leppaniemi, AS Doria, AW Kirkpatrick, AW Kirkpatrick, B Clyne, B Gutiérrez-Gutiérrez, B Joseph, B Jung, B Lamme, B Siewert, B Singh, B Tellor, BA Latenser, Boris Sakakushev, BR Andersen, BR Shah, BR Swenson, BR Toorenvliet, Bruno M. Pereira, C Dahyot-Fizelier, C Eckmann, C Eckmann, C Marshall, C Martin, C Simillis, C Wilasrusmee, CA Gogos, CD Freeman, Christian Eckmann, CK Kum, CL Steinbach, CP Schneider, CS Andeweg, CV Brown, CW Chen, D Backer De, D Brandt, D Demetriades, D Johnson, D Mokart, D Oliak, D Plachouras, D Stefanidis, DG Weber, DJ Klein, DM Payen, DN Cruz, DN Cruz, DP Raymond, DS Lee, E Angenete, E Duke, E Finlayson, E Sandell, EA Deitch, EA Halm, EC Schuts, EJ Goldstein, ER Kuse, Ernest E. Moore, Ewen A. Griffiths, F Cao, F Coccolini, F Coccolini, F Menichetti, F Perez, F Zhou, FA Robledo, Fausto Catena, FC Riché, Federico Coccolini, Fikri M. Abu-Zidan, Francesco M. Labricciosa, FS Taccone, G Cavriani, G Grunau, G Guyatt, GA Noskin, Gabriele Sganga, GR Shirah, Gustavo P. Fraga, H Dupont, H Dupont, H Mazeh, H Wacha, HB Reith, HG Gaitán, HG Jeon, HH Stone, HO Davies, HS Koo, HT Cheng, I Martín-Loeches, I Morrissey, Ignacio Martin-Loeches, IH Celik, J Bailey, J Barbić, J Garnacho-Montero, J Garnacho-Montero, J Karjagin, J Kenig, J Ruiter de, J Ruiz, J Solomkin, J Steppan, J Suliburk, J Theisen, J Waele De, JA Carr, JA Kellum, JA Lujan, Jan J. De Waele, Jan Ulrych, JC Andersen, JC Marshall, JC Mayberry, JE Mazuski, Jean-Louis Vincent, Jeffry Kashuk, JJ Atema, JJ Kim, JJ Schentag, JJ Waele De, JK Kim, JK Schultz, JL Regner, JL Vincent, JL Vincent, JL Vincent, JL Vincent, JM Burch, JM Dulhunty, JM Dulhunty, JM Regimbeau, JM Wagner, John Mazuski, JR Aunan, JS Farhat, JS Solomkin, K Das, K Ikawa, K Jansson, K Pontikis, K Soreide, K Thorsen, K Thorsen, K Tschaikowsky, KF Desserud, KG Kreymann, Kjetil Soreide, KW Garey, L Ansaloni, L Leibovici, L Lorente, LC McDonald, LM Burke, Luca Ansaloni, M Bassetti, M Bassetti, M Bezmarevic, M Ceresoli, M Johansson, M Knoke, M Kollef, M Kologlu, M Leone, M Leone, M Ortega, M Paul, M Sartelli, M Sartelli, M Sartelli, M Sartelli, M Sartelli, M Sartelli, M Sartelli, M Singer, M Zalacain, MA Boermeester, MA Gladman, MA Puskarich, Maddalena Giannella, Marco Ceresoli, Marja A. Boermeester, Mark Malangoni, Massimo Girardis, Massimo Sartelli, MC Birmingham, ME Falagas, ME Falagas, MF Kaffarnik, MH Al-Temimi, MH Møller, MH Scheetz, Michael Sugrue, MJ Dortch, MM Alejandria, MM Levy, MN Al-Hasan, MP Fink, MS Bleszynski, MS Scepanovic, N Patel, O Lortholary, O Ruler Van, O Ruler Van, O Ruler Van, Osvaldo Chiara, P Ambrosetti, P Augustin, P Davey, P Kaufmann, P Montravers, P Montravers, P Montravers, P Montravers, P Montravers, P Montravers, P Montravers, P Montravers, P Pessaux, P Ravishankaran, P Seguin, P Seguin, P Sridharan, PA Gross, PC McGovern, PG Pappas, PG Pappas, PH Reemst, Philippe Montravers, Pierluigi Viale, PJ Carroll, PM Lepper, PS Barie, PS Barie, R Ben-Ami, R Ferrer, R Ferrer, R Kaki, R Kullar, R Sarbinowski, RC Bone, RG Holzheimer, RG Sawyer, RJ Burnett, RM Klevens, Ronald V. Maier, RP Dellinger, S Bailly, S Biondo, S Blot, S Blot, S Busani, S Dharmarajan, S Gupta, S Mulier, S Sauerland, S Saverio Di, S Scheingraber, S Vennix, S Vennix, Salomone Di Saverio, SL Buijk, SL Pestotnik, SP Mishra, SR Kristjansson, SR Weingarten, T Cardoso, T Hendriks, T Kiviluoto, T Koperna, T Orouji Jokar, T Yamamoto, T Yamamoto, Tarcisio Reis, TE Rix, TJ Crofts, TJ Marrie, TN Robinson, TP Lodise Jr, V Golash, V Manganelli, V Sallinen, V Shani, VB Torres, VJ Sallinen, Vladimir Khokha, W Laméris, Walter L. Biffl, Y Albayrak, Y Dubrovskaya, Y Mawal, YA Gul, Yoram Kluger, YP Chong, Z Peng, Z Popovski, Z Xiao   +319 more
core   +4 more sources

Antibiotic Resistance: A Genetic and Physiological Perspective

MedComm, Volume 6, Issue 11, November 2025.
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy, Ahmed H. El‐Sappah, Rong Guo, Xiaoling Luo, Shiyuan Deng, Meifang Du, Xiaohong Jian, Mohammed Bakeer, Zaixin Li, Zhi Zhang   +9 more
wiley   +1 more source