Results 121 to 130 of about 8,708 (251)

Role of Class I, II and III Integrons in Multidrug Resistance in Pseudomonas aeruginosa Isolated from Nosocomial Hospital [PDF]

, 2016
Aims: The increasing usage of antibiotics can cause resistance to the treatment of infections, which can caused by bacteria, e.g. Pseudomonas aeruginosa. The aim of this study was to trace the class I, II and III integrons in isolates of P. aeruginosa of
Momtaz, H., Nourbakhsh, F.
core   +1 more source

Spotlight commentary: Treatment of multidrug‐resistant Gram‐negative infections in the era of growing antimicrobial resistance

British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2485-2489, September 2025.
Luka Bielen, Andro Vujević, Luka Csenar
wiley   +1 more source

Efficacy of species-specific protein antibiotics in a murine model of acute Pseudomonas aeruginosa lung infection [PDF]

, 2016
Protein antibiotics, known as bacteriocins, are widely produced by bacteria for intraspecies competition. The potency and targeted action of bacteriocins suggests that they could be developed into clinically useful antibiotics against highly drug ...
Douce, GR, Evans, TJ, McCaughey, LC, Ritchie, ND, Walker, D   +4 more
core   +3 more sources

Ceftolozane/Tazobactam for the Treatment of Adults With Cystic Fibrosis: Results From a French Prospective Cohort Study

Open Forum Infectious Diseases
Background People with cystic fibrosis (pwCF) are particularly susceptible to respiratory infections, including those caused by multidrug-resistant (MDR) pathogens.
Pierre-Régis Burgel, X. Bourge, Carole Mackosso, Francois Parquin   +3 more
semanticscholar   +1 more source

Use of ceftolozane-tazobactam in a cystic fibrosis patient with multidrug-resistant pseudomonas infection and renal insufficiency

Respiratory Medicine Case Reports, 2018
We report the successful use of ceftolozane/tazobactam (C/T) to treat a pulmonary exacerbation in a 35 year old female, post lung transplant, with cystic fibrosis (CF), malnutrition, chronic kidney disease, and multi-drug resistant Pseudomonas aeruginosa
Katie Stokem, Jonathan B. Zuckerman, David P. Nicolau, Minkey Wungwattana, Edmund H. Sears   +4 more
doaj   +1 more source

OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli [PDF]

, 2018
Background ESBL-producing Escherichia coli have expanded globally since the turn of the century and present a major public health issue. Their in vitro susceptibility to penicillin/inhibitor combinations is variable, and clinical use of these ...
Cleary, Paul, Day, Michaela, Doumith, Michel, Hopkins, Katie L, Livermore, David M, Toleman, Mark A, Wareham, David W, Wiuff, Camilla, Woodford, Neil   +8 more
core   +3 more sources

Analysis of patients with diabetes and complicated intra-abdominal infection or complicated urinary tract infection in phase 3 trials of ceftolozane/tazobactam

BMC Infectious Diseases, 2017
Background Diabetes mellitus and hyperglycemia are associated with increased susceptibility to bacterial infections and poor treatment outcomes. This post hoc evaluation of the treatment of complicated intra-abdominal infections (cIAI) and complicated ...
Myra W. Popejoy, Jianmin Long, Jennifer A. Huntington   +2 more
doaj   +1 more source

The impact of a computerised test of attention and activity (QbTest) on diagnostic decision-making in children and young people with suspected ADHD: single-blind randomised controlled trial [PDF]

, 2018
Background: Diagnosis of attention deficit hyperactivity disorder (ADHD) relies on subjective methods which can lead to diagnostic uncertainty and delay.
AQUA Trial Group, Boadu, Janet, Brown, Nikki, Daley, David, Groom, Madeleine J., Guo, Boliang, Hall, Charlotte L., Hollis, Chris, James, Marilyn, Kaylor-Hughes, Catherine, Moldavsky, Maria, Morriss, Richard, Sayal, Kapil, Valentine, Althea Z., Walker, Gemma M.   +14 more
core   +2 more sources

Activity of ceftolozane/tazobactam and imipenem/relebactam against clinical isolates of Enterobacterales and Pseudomonas aeruginosa collected in Greece and Italy—SMART 2017–2021

European Journal of Clinical Microbiology and Infectious Diseases
The current study evaluated the in vitro activities of ceftolozane/tazobactam (C/T), imipenem/relebactam (IMI/REL), and comparators against recent (2017–2021) clinical isolates of gram-negative bacilli from two countries in southern Europe. Nine clinical
J. Karlowsky, S. Lob, S. Hawser, N. Kothari, F. Siddiqui, I. Alekseeva, C. DeRyke, K. Young, M. Motyl, D. Sahm   +9 more
semanticscholar   +1 more source

Targeting antibiotic resistance [PDF]

, 2016
Finding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health.
Chellat, Mathieu F., Raguž, Luka, Riedl, Rainer   +2 more
core   +1 more source