Results 101 to 110 of about 8,708 (251)

Cost-effectiveness of ceftolozane/tazobactam compared with piperacillin/tazobactam as empiric therapy based on the in-vitro surveillance of bacterial isolates in the United States for the treatment of complicated urinary tract infections

BMC Infectious Diseases, 2017
Background A challenge in the empiric treatment of complicated urinary tract infection (cUTI) is identifying the initial appropriate antibiotic therapy (IAAT), which is associated with reduced length of stay and mortality compared with initial ...
Teresa L Kauf, Vimalanand S. Prabhu, Goran Medic, Rebekah H. Borse, Benjamin Miller, Jennifer Gaultney, Shuvayu S. Sen, Anirban Basu   +7 more
doaj   +1 more source

Successful Management of Steroid‐Refractory Immune‐Related Pneumonitis With Mycophenolate Mofetil: A Case Report

Respirology Case Reports, Volume 13, Issue 4, April 2025.
Herein, we report the case of an 82‐year‐old male with pleural mesothelioma who developed steroid‐refractory immune‐related pneumonitis after treatment with ipilimumab and nivolumab, which was successfully managed by mycophenolate mofetil treatment. ABSTRACT Steroid‐refractory immune‐related pneumonitis is a clinical challenge with limited evidence ...
Hiroaki Ota, Daichi Fujimoto, Yoshiki Negi, Takashi Murata, Mayuko Tokuda, Tomoki Higashiyama, Akio Tada, Toshiyuki Minami, Taiichiro Otsuki, Koji Mikami, Ryo Takahashi, Kozo Kuribayashi, Takashi Kijima   +12 more
wiley   +1 more source

Ceftolozane/Tazobactam Activity Against Drug-Resistant Pseudomonas aeruginosa and Enterobacterales Causing Healthcare-Associated Infections in Eight Asian Countries: Report from an Antimicrobial Surveillance Program (2016–2018)

Infection and Drug Resistance, 2022
Michael Pfaller,1,2 Dee Shortridge,1 Wei-Ting Chen,3 Helio Sader,1 Mariana Castanheira1 1JMI Laboratories, North Liberty, IA, USA; 2University of Iowa College of Medicine, Iowa City, IA, USA; 3Merck & Co., Inc, Kenilworth, NJ, USACorrespondence: Dee ...
Pfaller M, Shortridge D, Chen WT, Sader H, Castanheira M   +4 more
doaj  

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone [PDF]

, 2017
Emergence of epidemic clones and antibiotic resistance development compromises the management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections.
Cabot, Gabriel, Cantón, Rafael, Figuerola, Joan, Johansen, Helle Krogh, Kidd, Timothy J., López-Causapé, Carla, Madsen Sommer, Lea Mette, Molin, Søren, Ocampo-Sosa, Alain A., Oliver, Antonio, Rubio, Rosa   +10 more
core   +1 more source

Epidemiology, Treatment, and Outcomes of Gram‐Negative Bacteremia in a Multicenter Cohort of Solid Organ Transplant Recipients

Clinical Transplantation, Volume 39, Issue 4, April 2025.
ABSTRACT Introduction Little is known about the epidemiology and management of gram‐negative bloodstream infections (GN‐BSIs) in patients after solid organ transplant (SOT). We describe epidemiology, treatment approaches, and outcomes in a subset of patients with SOT from a larger cohort with GN‐BSI. Methods This was a multicenter, retrospective cohort
Sarah B. Doernberg, Emily L. Heil, Suiyini Fiawoo, Jae Hyoung Lee, Sara E. Cosgrove, David M. Dobrzynski, Yihan Li, Ryan K. Shields, Emily S. Spivak, Erica J. Stohs, Pranita D. Tamma, Erin K. McCreary   +11 more
wiley   +1 more source

Perspectives on the use of ceftolozane/tazobactam: a review of clinical trial data and real-world evidence

Future Microbiology
Hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP) are common healthcare-associated infections linked to high morbidity and mortality.
I. Martín-Loeches, C. Bruno, Andrew Deryke   +2 more
semanticscholar   +1 more source

Chemical Stability of Ceftolozane/Tazobactam in Polyvinylchloride Bags and Elastomeric Pumps

Current Therapeutic Research, 2017
Background: Elastomeric pumps are often used to administer intravenous antibiotics in the outpatient setting, but effective infusion requires that the drug remain stable in solution throughout the procedure. Objective: To determine the chemical stability
Joseph Terracciano, PhD, Elizabeth G. Rhee, MD, Jacqueline Walsh, BA   +2 more
doaj   +1 more source

Potential strategies for the eradication of multi-drug resistant Gram-negative bacterial infections [PDF]

, 2016
Antimicrobial resistance is one of the leading threats to society. The increasing burden of multidrug-resistant Gram-negative infection is particularly concerning as such bacteria are demonstrating resistance to nearly all currently licensed therapies ...
Gilmore, Brendan F., Huwaitat, Rawan, Laverty, Garry, McCloskey, Alice P.   +3 more
core   +1 more source

Infections Management in the Lung Transplant Setting in Italy: A Web‐Survey

Transplant Infectious Disease, Volume 27, Issue 2, March/April 2025.
A web survey has revealed significant variation in infection management practices across Italian lung transplant centers. These differences encompass key aspects of infection prevention and control, including antibiotic protocols and cytomegalovirus prophylaxis, underscoring a lack of consistency in fundamental strategies.
Andrea Lombardi, Paolo Grossi, Malgorzata Mikulska, Maddalena Giannella, Renato Pascale, Serena Marinello, Francesca Montagnani, Elena Seminari, Silvia Corcione, Alessandra Bandera, Alessandro Bertani, Alessandra Mularoni, for the Infection Prevention and Treatment Working Group of the LUNG‐SITO study group   +12 more
wiley   +1 more source

Molecular characterization of clinically isolated Pseudomonas aeruginosa with varying resistance to ceftazidime-avibactam and ceftolozane-tazobactam collected as a part of the ATLAS global surveillance program from 2020 to 2021

Antimicrobial Agents and Chemotherapy
Ceftazidime-avibactam (CZA) and ceftolozane-tazobactam (C/T) are important agents for treating multidrug-resistant P. aeruginosa infections. In this study, we evaluated the molecular characteristics of 300 globally collected clinical P.
H. Li, A. Oliver, R. K. Shields, S. Kamat, G. Stone, M. Estabrook   +5 more
semanticscholar   +1 more source