Ceftriaxone-Resistant Salmonella enterica Serotype Newport, France [PDF]
The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase (Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans in France during 2000–2005. Because this strain was not detected in food
Svetlana Egorova +13 more
doaj +3 more sources
Ceftriaxone-induced Agranulocytosis [PDF]
Ceftriaxone is a widely used antibiotic regarded as safe and effective. Drug-induced agranulocytosis is a life-threatening adverse reaction and few reports related to ceftriaxone were found in a review of the literature.
Teixeira, Carolina +6 more
core +1 more source
Penicillin-Susceptible Streptococcus pneumoniae Meningitis in Adults: Does the Ceftriaxone Dosing Matter? [PDF]
The recommended empiric ceftriaxone dosing regimen for acute bacterial meningitis in adults is 2 g every 12 h. After penicillin-susceptible Streptococcus pneumoniae is isolated as a causative microorganism, the ceftriaxone dose may be continued or ...
Carlo Casanova +17 more
core +1 more source
Ceftriaxone dosing in patients admitted from the emergency department with sepsis [PDF]
PURPOSE: Unbound ceftriaxone pharmacokinetics in adult patients have been poorly characterised. The objective of this study is to determine the ceftriaxone dose that achieves an unbound trough concentration ≥ 0.5 mg/L in > 90% of adult patients receiving
Ungerer, Jacobus +8 more
core +1 more source
Perioperative infection prophylaxis and risk factor impact in colon surgery [PDF]
Background: A prospective observational study was undertaken in 2,481 patients undergoing elective colon resection in 114 German centers to identify optimal drug and dosing modalities and risk factors for postoperative infection.
Rau, H. G. +5 more
core +1 more source
Pharmacodynamics of ceftriaxone for the treatment of methicillin-susceptible Staphylococcus aureus: is it a viable treatment option? [PDF]
Ceftriaxone is a broad-spectrum cephalosporin that may be one option to treat methicillin-susceptible Staphylococcus aureus (MSSA). Although MSSA may be susceptible to ceftriaxone, the minimum inhibitory concentration (MIC) is generally two- to four-fold
Heffernan, AJ +7 more
core +1 more source
Combination of daptomycin plus ceftriaxone is more active than vancomycin plus ceftriaxone in experimental meningitis after addition of dexamethasone [PDF]
We examined the cerebrospinal fluid penetration of daptomycin after the addition of dexamethasone and its bactericidal efficacy with and without ceftriaxone in an experimental rabbit model of pneumococcal meningitis.
Cottagnoud, M +7 more
core +1 more source
Multicenter Population Pharmacokinetic Study of Unbound Ceftriaxone in Critically Ill Patients [PDF]
The objective of this study was to describe the total and unbound population pharmacokinetics of ceftriaxone in critically ill adult patients and to define optimized dosing regimens.
Joynt, Gavin M. +14 more
core +1 more source
Ceftriaxone and Melittin Synergistically Promote Wound Healing in Diabetic Rats
High glucose levels in diabetic patients are implicated in delay wound healing that could lead to more serious clinical complications. The aim of the present work was to examine the formulation of ceftriaxone (CTX) and melittin (MEL) as nanoconjugate ...
Nabil A. Alhakamy +11 more
doaj +1 more source
Introduction: Enteric fever caused by Salmonella enterica continues to be a major public health problem worldwide. In the last decade, ceftriaxone and azithromycin have become the drugs of choice for treating enteric fever caused by Nalidixic acid ...
Rashmi Shankar Kokare +4 more
doaj +1 more source

