Optimization of Lipid-Based Ceftriaxone Delivery System via Machine Learning
Ceftriaxone (CTX) a third-generation cephalosporin, is a broad-spectrum antibiotic that can be administered via intramuscular or intravenous routes to treat various types of infection.
Daniela R. P. Loureiro +4 more
doaj +1 more source
Removal of ceftriaxone and ciprofloxacin antibiotics from aqueous solutions using graphene oxide derived from corn cob [PDF]
BACKGROUND AND OBJECTIVES: Preliminary studies on the exploration of carbonaceous materials from agricultural waste and their use as adsorbents for antibiotic removal have shown the potential to address a new threat to human health due to antibiotic ...
. Rinawati +6 more
doaj +1 more source
Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague
Plague pandemics and outbreaks have killed millions of people during the history of humankind. The disease, caused by the bacteria Yersinia pestis, is currently treated effectively with antibiotics.
Yaron Vagima +14 more
doaj +1 more source
John F Kokai-Kun,1 Chenxiong Le,1 Kenneth Trout,1 Julia L Cope,2 Nadim J Ajami,2 Andrew J Degar,2 Sheila Connelly1 1Synthetic Biologics, Inc., Rockville, MD, USA; 2Diversigen, Inc., Houston, TX, USACorrespondence: Sheila Connelly Email sconnelly ...
Kokai-Kun JF +6 more
doaj
Novel 7-{[2-(4-hydroxyphenyl)methylidene]amino}-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by ...
Ghulam Fareed +4 more
doaj +1 more source
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Brain function is compromised in myotonic dystrophy type 1 (DM1), but the underlying mechanisms are not fully understood. To gain insight into the cellular and molecular pathways primarily affected, we studied a mouse model of DM1 and brains of adult ...
Géraldine Sicot +18 more
doaj +1 more source
Phenotypic and genotypic characterisation of Neisseria gohorrhoeae isolates from New Zealand with reduced susceptibility to ceftriaxone : a thesis submitted to the College of Health in partial fulfilment of the requirements for the Master of Science in Microbiology at Massey University, New Zealand [PDF]
Objectives Currently, ceftriaxone is the last remaining drug recommended for empirical treatment of gonorrhoea. Neisseria gonorrhoeae with reduced susceptibility to ceftriaxone have been isolated worldwide in countries such as Japan, France, Spain ...
Mohd Jamaludin, Norshuhaidah bt
core
ABSTRACT Background To mitigate the progression of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD), appropriate drain management is required, and exchanging drainage tubes is commonly performed. However, the optimal timing of the first drain exchange has not yet been determined.
Taihei Soma +7 more
wiley +1 more source
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats
Background Perinatal brain injury is the leading cause of subsequent neurological disability in both term and preterm baby. Glutamate excitotoxicity is one of the major factors involved in perinatal hypoxic-ischemic encephalopathy (HIE).
Huang Yen +5 more
doaj +1 more source

